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Follistatin

A broadly distributed protein that binds directly to ACTIVINS. It functions as an activin antagonist, inhibits FOLLICLE STIMULATING HORMONE secretion, regulates CELL DIFFERENTIATION, and plays an important role in embryogenesis. Follistatin is a single glycosylated polypeptide chain of approximately 37-kDa and is not a member of the inhibin family (INHIBINS). Follistatin also binds and neutralizes many members of the TRANSFORMING GROWTH FACTOR BETA family.
Also Known As:
Activin Binding Protein; Activin-Binding Protein
Networked: 704 relevant articles (28 outcomes, 123 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Hedger, Mark P: 16 articles (01/2020 - 10/2007)
2. de Kretser, David M: 16 articles (06/2017 - 10/2004)
3. Phillips, David J: 15 articles (01/2016 - 10/2004)
4. Mantzoros, Christos S: 11 articles (01/2021 - 01/2016)
5. Petraglia, Felice: 11 articles (09/2015 - 08/2004)
6. de Kretser, D M: 10 articles (01/2016 - 04/2000)
7. Ning, Wen: 9 articles (11/2021 - 04/2013)
8. Gregorevic, Paul: 9 articles (04/2021 - 06/2012)
9. Reis, Fernando M: 9 articles (01/2018 - 05/2007)
10. Groome, N P: 9 articles (11/2002 - 04/2000)

Related Diseases

1. Fibrosis (Cirrhosis)
2. Inflammation (Inflammations)
3. Hypertrophy
4. Myocardial Infarction
5. Inclusion Body Myositis

Related Drugs and Biologics

1. Activins (Activin)
2. Proteins (Proteins, Gene)
3. Myostatin
4. activin A
5. Inhibins (Inhibin)
6. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
7. Carrier Proteins (Binding Protein)
8. Intercellular Signaling Peptides and Proteins (Growth Factors)
9. Ligands
10. Collagen

Related Therapies and Procedures

1. Therapeutics
2. Radiotherapy
3. Denervation
4. Tenotomy
5. Bariatric Surgery