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Follistatin

A broadly distributed protein that binds directly to ACTIVINS. It functions as an activin antagonist, inhibits FOLLICLE STIMULATING HORMONE secretion, regulates CELL DIFFERENTIATION, and plays an important role in embryogenesis. Follistatin is a single glycosylated polypeptide chain of approximately 37-kDa and is not a member of the inhibin family (INHIBINS). Follistatin also binds and neutralizes many members of the TRANSFORMING GROWTH FACTOR BETA family.
Also Known As:
Activin Binding Protein; Activin-Binding Protein
Networked: 371 relevant articles (13 outcomes, 59 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Phillips, David J: 14 articles (07/2015 - 10/2004)
2. Petraglia, Felice: 11 articles (09/2015 - 08/2004)
3. de Kretser, David M: 10 articles (07/2015 - 10/2004)
4. Hedger, Mark P: 9 articles (07/2015 - 10/2007)
5. Groome, N P: 9 articles (11/2002 - 04/2000)
6. de Kretser, D M: 8 articles (06/2013 - 04/2000)
7. Reis, Fernando M: 7 articles (08/2012 - 05/2007)
8. Kojima, Itaru: 6 articles (01/2014 - 12/2002)
9. Phillips, D J: 6 articles (07/2006 - 05/2000)
10. Walsh, Kenneth: 5 articles (07/2014 - 03/2011)

Related Diseases

1. Fibrosis (Cirrhosis)
2. Neoplasms (Cancer)
3. Inflammation
4. Colitis
5. Wounds and Injuries (Trauma)

Related Drugs and Biologics

1. Activins (Activin)
2. activin A
3. Myostatin
4. Inhibins (Inhibin)
5. Carrier Proteins (Binding Protein)
6. Intercellular Signaling Peptides and Proteins (Growth Factors)
7. Transforming Growth Factor beta (TGF-beta)
8. Losartan (Cozaar)
9. Interleukin-10 (Interleukin 10)
10. Peroxidase (Myeloperoxidase)

Related Therapies and Procedures

1. Denervation
2. Tenotomy
3. Transplants (Transplant)
4. Heterologous Transplantation (Xenotransplantation)
5. Intraventricular Infusions