|1.||Lehtiö, Lari: 5 articles (07/2015 - 02/2012)|
|2.||Haikarainen, Teemu: 5 articles (07/2015 - 10/2013)|
|3.||Narwal, Mohit: 4 articles (01/2014 - 02/2012)|
|4.||Joensuu, Päivi: 3 articles (01/2014 - 10/2013)|
|5.||Venkannagari, Harikanth: 3 articles (12/2013 - 02/2012)|
|6.||Wood, Pauline J: 2 articles (07/2015 - 12/2013)|
|7.||Threadgill, Michael D: 2 articles (07/2015 - 12/2013)|
|8.||Lloyd, Matthew D: 2 articles (07/2015 - 12/2013)|
|9.||Thompson, Andrew S: 2 articles (07/2015 - 12/2013)|
|10.||Nathubhai, Amit: 2 articles (07/2015 - 12/2013)|
01/15/2015 - "Together, our study revealed a new regulation of PTEN and highlighted a role for tankyrases in the PTEN-AKT pathway that can be explored further for cancer treatment."
07/01/2015 - "The three principal protein substrates of the tankyrases (TRF1, NuMA and axin) are involved in replication of cancer cells; thus inhibitors of the tankyrases may have anticancer activity. "
11/01/2014 - "Human tankyrases 1 and 2 (TNKS1/2) are attractive pharmacological biotargets, especially for the treatment of specific types of cancer. "
06/15/2014 - "Inhibiting Tankyrases sensitizes KRAS-mutant cancer cells to MEK inhibitors via FGFR2 feedback signaling."
01/01/2014 - "Tankyrases: structure, function and therapeutic implications in cancer."
|2.||Colorectal Neoplasms (Colorectal Cancer)
|3.||Lung Neoplasms (Lung Cancer)
09/01/2013 - "Inactivation of tankyrases reduces experimental fibrosis by inhibiting canonical Wnt signalling."
09/01/2013 - "Inactivation of tankyrases prevented the activation of canonical Wnt signalling in experimental fibrosis and reduced the nuclear accumulation of β-catenin and the mRNA levels of the target gene c-myc. "
09/01/2013 - "The antifibrotic effects of the tankyrase inhibitor XAV-939 or of siRNA-mediated knockdown of tankyrases were evaluated in the mouse models of bleomycin-induced dermal fibrosis and in experimental fibrosis induced by adenoviral overexpression of a constitutively active TGF-β receptor I (Ad-TBRI). "
|5.||Colonic Neoplasms (Colon Cancer)
|1.||Adenosine Diphosphate (ADP)
|2.||Small Interfering RNA (siRNA)
|3.||Messenger RNA (mRNA)
|4.||Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)