|1.||Brain Injuries (Brain Injury)
|2.||Post-Traumatic Stress Disorders (PTSD)
|3.||Closed Head Injuries
|4.||Substance-Related Disorders (Drug Abuse)
|5.||Wounds and Injuries (Trauma)
|1.||Harch, Paul G: 4 articles (12/2013 - 01/2009)|
|2.||Ben-Jacob, Eshel: 2 articles (11/2015 - 01/2013)|
|3.||Efrati, Shai: 2 articles (11/2015 - 01/2013)|
|4.||Crawford, Susan: 2 articles (01/2014 - 01/2014)|
|5.||Dewey, Deborah: 2 articles (01/2014 - 01/2014)|
|6.||Barlow, Karen M: 2 articles (01/2014 - 01/2014)|
|7.||Borg, Jörgen: 2 articles (09/2013 - 01/2013)|
|8.||Stålnacke, Britt-Marie: 2 articles (01/2013 - 09/2005)|
|9.||Wolf, George: 2 articles (11/2012 - 07/2012)|
|10.||Profenna, Leonardo: 2 articles (11/2012 - 11/2012)|
|1.||salicylhydroxamic acid (SHAM)IBA
07/01/2012 - "The DoD's four randomized controlled trials will enroll a total of 242 service members with post-concussion syndrome and expose them to a range of control, sham and HBO2 conditions for 40 sessions over a period of eight to 11 weeks. "
12/01/2013 - "Hyperbaric oxygen therapy for post-concussion syndrome: contradictory conclusions from a study mischaracterized as sham-controlled."
09/01/2013 - "Hyperbaric oxygen therapy no better than sham in improving post-concussion symptoms following mild traumatic brain injury."
11/01/2012 - "To catalog the side effects of 2.4 atmospheres absolute (atm abs) hyperbaric oxygen (HBO2) vs. sham on post-concussion symptoms in military service members with combat-related, mild traumatic brain injury (TBI). "
07/01/2012 - "Hyperbaric oxygen for post-concussion syndrome: design of Department of Defense clinical trials."
09/01/2013 - "Hyperbaric oxygen (HBO2) for post-concussive syndrome/chronic TBI--product summary."
11/04/2015 - "Hyperbaric oxygen may induce angiogenesis in patients suffering from prolonged post-concussion syndrome due to traumatic brain injury."
11/20/2012 - "Air Force School of Aerospace Medicine, the effects of 2.4 atmospheres absolute (ATA) hyperbaric oxygen (HBO₂) on post-concussion symptoms in 50 military service members with at least one combat-related, mild traumatic brain injury were examined. "
01/01/2010 - "Further investigation into the use of hyperbaric oxygen as a novel therapy for the secondary prevention of post-traumatic stress disorder that often accompanies post-concussive syndrome may be warranted. "
|3.||Biological Markers (Surrogate Marker)IBA
12/01/2015 - "This study explored whether acute serum marker S100B is related with post-concussive symptoms (PCS) and neuropsychological performance 4 months after paediatric mild traumatic brain injury (mTBI). "
07/01/2013 - "There are no established biomarkers for mild traumatic brain injury (mTBI), in part because post-concussive symptoms (PCS) are subjective and conventional imaging is typically unremarkable. "
08/01/2006 - "Serum biochemical markers for post-concussion syndrome in patients with mild traumatic brain injury."
|4.||Technetium Tc 99m Exametazime (Ceretec)FDA Link
02/01/1997 - "The purposes of this study were: (1) to determine the prevalence of abnormal 99mTc-HMPAO SPECT scans in patients suffering from persistent post-concussive syndrome (PPCS) after mild closed head injury (CHI); (2) to compare SPECT with structural neuroimaging (MRI and CT) in patients with mild CHI; and (3) to investigate correlations between SPECT and clinical data obtained from the patient sample (neuropsychological testing, demographics, psychiatric diagnoses). "
|5.||17-Ketosteroids (17 Ketosteroids)IBA
01/01/2014 - "A double-blind, placebo-controlled intervention trial of 3 and 10 mg sublingual melatonin for post-concussion syndrome in youths (PLAYGAME): study protocol for a randomized controlled trial."
01/01/2014 - "The aim of this study is to determine if treatment with melatonin improves post-concussion syndrome in youths following mild traumatic brain injury. "
01/01/2014 - "Our hypothesis is that treatment of post-concussion syndrome following mild traumatic brain injury with 3 or 10 mg of sublingual melatonin for 28 days will result in a decrease in post-concussion syndrome symptoms compared with placebo. "
09/01/2013 - "Clinical outcome was assessed by the Rivermead Post-Concussion Symptoms Questionnaire (RPQ), Hospital Anxiety and Depression Scale (HADS) and Glasgow Outcome Scale Extended (GOSE). "
01/01/2011 - "Clinical and demographic information was collected and participants completed a range of questionnaires (Revised Illness Perceptions Questionnaire, Brief COPE, Rivermead Post-Concussion Symptoms Questionnaire, Rivermead Follow-Up Questionnaire and HADS). "
06/01/2009 - "The Rivermead Post Concussion Symptoms Questionnaire (RPQ) and Hospital Anxiety and Depression Scale (HADS) were administered. "
05/01/2008 - "patients were asked to fill out questionnaires to assess quality of life (SF36), anxiety and depression (HADS), and signs and symptoms of post-concussion syndrome. "
01/01/2010 - "Participants completed the Fatigue Severity Scale (FSS), Rivermead Post-concussion Symptoms Questionnaire (RPSQ), Hospital Anxiety and Depression Scale (HADS) and the Short Form 36 Health Survey-Version 2 (SF-36v2). "
11/01/2013 - "Persistent post-concussion syndrome (PCS) is considered as a somatoform presentation, influenced by the non-specificity of PCS symptoms which commonly occur in non-TBI samples and co-vary as a function of general life stress, and psychological factors including symptom expectation, depression and anxiety. "
09/01/2015 - "Management of persistent post-concussive symptoms (PCS) has been a challenge to healthcare providers throughout the Military and Veterans Healthcare Systems, as well as civilian healthcare providers, due in part to the chronic nature of symptoms, co-occurrence of behavioral health disorders such as depression, Posttraumatic Stress Disorder (PTSD), and substance use disorders, and fear of a potential stigma associated with psychiatric diagnoses and behavioral health treatment(s). "
02/01/2005 - "The post-concussion syndrome in Lithuania redux."
01/01/2015 - "Hyperbaric oxygen therapy for post concussion symptoms: issues may affect the results."
01/01/2014 - "Hyperbaric oxygen therapy for chronic post-concussive syndrome."
01/01/2014 - "In this editorial, the value of hyperbaric oxygen therapy in the management of chronic post-concussive syndrome following mild traumatic brain injury is discussed. "
01/01/2013 - "Hyperbaric oxygen therapy can improve post concussion syndrome years after mild traumatic brain injury - randomized prospective trial."
10/10/2012 - "Response to the letter to the editor by Armistead-jehle and Lee on Harch et Al., "A phase I study of low-pressure hyperbaric oxygen therapy for blast-induced post-concussion syndrome and post-traumatic stress disorder"."
|2.||Ambulatory Care (Outpatient Care)
|3.||Activities of Daily Living (ADL)
10/01/2009 - "Poorer eye movement function, and particularly poorer subcortical oculomotor function, correlated more with post-concussive symptom load and problems on activities of daily living whilst poorer neuropsychological function exhibited slightly better correlations with measures of mental health. "
03/01/2011 - "One aim was to describe changes over time after mild traumatic brain injuries in terms of the extent of persisting post-concussion symptoms, life satisfaction, perceived health, activities of daily living, changes in life roles and sick leave. "