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alpha-Crystallins (alpha-Crystallin)

A subclass of crystallins that provides the majority of refractive power and translucency to the lens (LENS, CRYSTALLINE) in VERTEBRATES. Alpha-crystallins also act as molecular chaperones that bind to denatured proteins, keep them in solution and thereby maintain the translucency of the lens. The proteins exist as large oligomers that are formed from ALPHA-CRYSTALLIN A CHAIN and ALPHA-CRYSTALLIN B CHAIN subunits.
Also Known As:
alpha-Crystallin; alpha Crystallin; alpha Crystallins; Crystallins, alpha
Networked: 198 relevant articles (6 outcomes, 17 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Reddy, G Bhanuprakash: 7 articles (08/2008 - 04/2004)
2. Andley, Usha P: 6 articles (01/2020 - 10/2003)
3. Kumar, P Anil: 5 articles (12/2007 - 04/2004)
4. Reddy, P Yadagiri: 4 articles (08/2008 - 04/2004)
5. Kumar, M Satish: 4 articles (12/2007 - 04/2004)
6. Wilkinson, Katalin A: 4 articles (07/2007 - 02/2005)
7. Wilkinson, Robert J: 4 articles (07/2007 - 02/2005)
8. Harding, John J: 4 articles (05/2007 - 06/2002)
9. Yan, Hong: 4 articles (05/2007 - 12/2003)
10. Reljic, Rajko: 3 articles (01/2020 - 03/2004)

Related Diseases

1. Cataract (Cataracts)
2. Inflammation (Inflammations)
3. Infections
4. Tuberculosis (Tuberculoses)
5. Neurodegenerative Diseases (Neurodegenerative Disease)

Related Drugs and Biologics

1. Proteins (Proteins, Gene)
2. Crystallins (Crystallin)
3. Antigens
4. gamma-Crystallins
5. Immunoglobulin A (IgA)
6. Interferon-gamma (Interferon, gamma)
7. Carnosine
8. Amyloid (Amyloid Fibrils)
9. Tryptophan (L-Tryptophan)
10. IgA receptor (protein B)

Related Therapies and Procedures

1. Lenses
2. Therapeutics
3. Lasers (Laser)
4. Drug Therapy (Chemotherapy)
5. Slit Lamp