|1.||Tanaka, Toshihiro: 4 articles (03/2009 - 05/2004)|
|2.||Ozaki, Kouichi: 4 articles (03/2009 - 05/2004)|
|3.||Meitinger, Thomas: 3 articles (03/2009 - 08/2007)|
|4.||Nakamura, Yusuke: 3 articles (03/2009 - 05/2004)|
|5.||André, S: 2 articles (06/2012 - 02/2008)|
|6.||Sturm, Andreas: 2 articles (05/2009 - 12/2008)|
|7.||Dignass, Axel U: 2 articles (05/2009 - 12/2008)|
|8.||Hori, Masatsugu: 2 articles (03/2009 - 05/2004)|
|9.||Nobuyoshi, Masakiyo: 2 articles (03/2009 - 05/2004)|
|10.||Inoue, Katsumi: 2 articles (03/2009 - 05/2004)|
09/01/2007 - "LGALS2 functional variant rs7291467 is not associated with susceptibility to myocardial infarction in Caucasians."
08/01/2007 - "A putative risk genotype of the polymorphism in the LGALS2 gene (rs7291467; 3279T/C) was not associated with myocardial infarction (OR 0.98, 95% CI 0.83-1.16; P = 0.84). "
03/01/2007 - "Lack of association between LTA and LGALS2 polymorphisms and myocardial infarction in Japanese and Korean populations."
03/01/2009 - "Several genes involved in the lymphotoxin-alpha cascade (LTA, LGALS2, and PSMA6) have been linked with the risk of myocardial infarction. "
09/01/2007 - "Lymphotoxin-alpha and galectin-2 SNPs are not associated with myocardial infarction in two different German populations."
12/01/2008 - "Our study provides evidence that galectin-2 induces apoptosis in vivo and ameliorates acute and chronic murine colitis. "
12/01/2008 - "Galectin-2 induces apoptosis of lamina propria T lymphocytes and ameliorates acute and chronic experimental colitis in mice."
12/01/2008 - "During colitis, galectin-2 expression was reduced, but could be restored to normal levels by immunosuppressive treatment. "
12/01/2008 - "Here, we investigate the potential therapeutic effect of galectin-2 in experimental colitis. "
05/01/2009 - "Since it has been demonstrated that galectin-2 regulates cell-mediated inflammatory bowel disease and colitis in mice, we intended to investigate the role of galectin-2 in inflammatory cutaneous T cell-mediated immune responses. "
04/01/2009 - "In the present study, we examined whether the LGALS2 3279TT homozygote variant alone can influence the prevalence of ischaemic stroke, and whether it can interact somehow with the disadvantageous LTA 252GG homozygote variant. "
04/01/2009 - "The combination of the LGALS2 3279TT and LTA 252GG homozygote was significantly less frequent in the ischemic stroke group (1.56%) than in the controls (5.94%, p<0.00187; overall stroke group: crude OR: 0.25, 95% CI: 0.1-0.64; adjusted OR: 0.03, 95% CI: 0.025-0.71). "
04/01/2009 - "Galectin-2 3279TT variant protects against the lymphotoxin-alpha 252GG genotype associated ischaemic stroke."
05/01/2005 - "Four new susceptibility genes have been identified using genome-wide association studies or genome-wide linkage studies: LTA (encoding cytokine lymphotoxin-alpha) on 6p21.3 for MI; LGALS2 (encoding galectin-2, an LTA-interacting protein) on 22q12-q13 for MI; ALOX5AP (encoding 5-lipoxygenase activating protein involved in synthesizing potent pro-inflammatory leukotrienes) on 13q12-13 for MI and stroke; and PDE4D (encoding phosphodiesterase 4D) on 5q12 for ischemic stroke. "
|4.||Coronary Artery Disease (Coronary Atherosclerosis)
04/01/2012 - "Polymorphisms of LTA, LGALS2, and PSMA6 genes and coronary atherosclerosis: a pathological study of 1503 consecutive autopsy cases."
01/01/2015 - "Galectin-2 is a monocyte-expressed carbohydrate-binding lectin, for which increased expression is genetically determined and associated with decreased collateral arteriogenesis in obstructive coronary artery disease patients. "
02/01/2010 - "The objective was to assess the relationship of LTA gene, LGALS2 gene and coronary artery disease, using a meta-analysis. "
03/01/2007 - "These observations showed that, while the LTA 252GG genotype might modify the development of coronary atherosclerosis, the relation of LTA and LGALS2 to MI itself remained much less certain."
03/01/2007 - "On the other hand, the polymorphism of LGALS2 was not associated with the severity of coronary atherosclerosis. "
05/01/2005 - "Genome-wide association studies identified significant association for myocardiaI infarction with the LTA gene (encoding lymphotoxin-alpha), and a follow-up study found that an LTA-interacting gene, LGALS2 (encoding galectin-2), is also a susceptibility gene for myocardiaI infarction. "
07/01/2006 - "Several genetic and clinical studies implicate LTalpha, and its binding and regulatory partner galectin-2, as a risk factor in the pathogenesis of cardiovascular diseases including miocardial infarction, aortic aneurysm, and cerebral infarction. "
|1.||Galectin 2 (LGALS2)
|4.||Type 4 Cyclic Nucleotide Phosphodiesterases
|6.||Biological Markers (Surrogate Marker)
|7.||NM23 Nucleoside Diphosphate Kinases
|8.||Phosphatidylethanolamine Binding Protein
|9.||Proteasome Endopeptidase Complex (Proteasome)
|10.||Galectin 4 (LGALS4)