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Calreticulin

A multifunctional protein that is found primarily within membrane-bound organelles. In the ENDOPLASMIC RETICULUM it binds to specific N-linked oligosaccharides found on newly-synthesized proteins and functions as a MOLECULAR CHAPERONE that may play a role in PROTEIN FOLDING or retention and degradation of misfolded proteins. In addition calreticulin is a major storage form for CALCIUM and functions as a calcium-signaling molecule that can regulate intracellular calcium HOMEOSTASIS.
Also Known As:
55-kDa High-Affinity Calcium Binding Protein; CAB-63; CBP3 (Liver); Calcium-Binding Protein-3; Calregulin; ERp60; HACBP; cC1qR Protein; 55 kDa High Affinity Calcium Binding Protein; Calcium Binding Protein 3
Networked: 508 relevant articles (9 outcomes, 51 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Michalak, Marek: 14 articles (11/2015 - 12/2003)
2. Wu, T-C: 14 articles (01/2015 - 08/2004)
3. Zitvogel, Laurence: 14 articles (08/2013 - 01/2007)
4. Kroemer, Guido: 14 articles (05/2013 - 01/2007)
5. Hung, Chien-Fu: 10 articles (01/2015 - 08/2004)
6. Ferreira, Arturo: 10 articles (07/2014 - 03/2004)
7. Ghiringhelli, François: 9 articles (01/2013 - 01/2007)
8. Apetoh, Lionel: 9 articles (01/2013 - 01/2007)
9. Lee, Hsinyu: 8 articles (08/2015 - 02/2009)
10. Cazzola, Mario: 7 articles (11/2014 - 12/2013)

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5. Vaccinia

Related Drugs and Biologics

1. Antigens
2. Proteins (Proteins, Gene)
3. DNA (Deoxyribonucleic Acid)
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6. DNA Vaccines
7. Biological Markers (Surrogate Marker)
8. endoplasmic reticulum glycoprotein p72
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10. 1-phenyl-3,3-dimethyltriazene (PDT)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Ischemic Postconditioning
3. Immunomodulation
4. Radiotherapy
5. Immunotherapy