Mannose-Binding Lectins

A subclass of lectins that are specific for CARBOHYDRATES that contain MANNOSE.

Also Known As:

Mannose-Specific Lectin; Lectin, Mannose-Specific; Lectins, Mannose-Binding; Mannose Binding Lectins; Mannose Specific Lectin

Networked: 27 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Ahmed, Md Nasir: 1 article (02/2022)
2.	Jahan, Rownak: 1 article (02/2022)
3.	Nissapatorn, Veeranoot: 1 article (02/2022)
4.	Rahmatullah, Mohammed: 1 article (02/2022)
5.	Wilairatana, Polrat: 1 article (02/2022)
6.	Antonopoulos, Aristotelis: 1 article (01/2022)
7.	Brewin, John: 1 article (01/2022)
8.	Cao, Huan: 1 article (01/2022)
9.	Davie, Adam: 1 article (01/2022)
10.	Dell, Anne: 1 article (01/2022)

Related Diseases

1.	Infections 01/01/2020 - "Additionally, high-mannose-binding lectins possess a broad capacity to neutralize and prevent infection with contemporary H3N2 strains. " 02/11/2011 - "High mannose-specific lectin (KAA-2) from the red alga Kappaphycus alvarezii potently inhibits influenza virus infection in a strain-independent manner." 09/01/1990 - "This compound effectively inhibits both human immunodeficiency virus type 1 (HIV-1) and type 2 infection of cells in vitro at concentrations around 0.5 micrograms/ml. Moreover, the compound completely inhibits HIV-1-induced syncytium formation at a concentration of 1 microgram/ml. Competition experiments with 35S-labelled sulphoevernan revealed that the mannose-specific lectin from Narcissus pseudonarcissus prevented binding of sulphoevernan to HIV-1, whereas the antibody OKT4A did not reduce the amount of sulphoevernan bound to MT-2 cells. " 07/01/2002 - "The cDNA sequence was similar to a maize gene encoding a beta-glucosidase aggregating factor (BGAF), to jacalin-like mannose-binding lectins, and to several plant genes that respond to microbial infections. "
2.	Virus Diseases (Viral Diseases) 02/01/2007 - "Purification of 3 monomeric monocot mannose-binding lectins and their evaluation for antipoxviral activity: potential applications in multiple viral diseases caused by enveloped viruses." 02/01/2022 - "Apart from this, the complement lectin pathway is a "first line host defense" against the viral infection that is activated by mannose-binding lectins. " 04/01/2014 - "Serpins are also part of the early innate immune response to viral infection that includes mannose binding lectins, soluble CD14, defensins and antimicrobial peptides. "
3.	Atherosclerosis 11/01/2019 - "Mannose-binding lectins have attracted considerable attention against carcinogenesis and atherogenesis. " 03/01/2010 - "Accelerated atherosclerosis in rheumatoid arthritis: rationale for mannose-binding lectins?"
4.	HIV Infections (HIV Infection) 01/01/2018 - "Although it has been shown that some mannose-binding lectins (MBLs) exhibit significant activity against HIV infection, little is known about whether N-acetylgalactosamine (GalNAc)-binding lectins have the ability to inhibit HIV infection. " 02/01/2006 - "The anti-human immunodeficiency virus (HIV) I/II activity of a mannose and sialic acid binding lectin isolated from rhizomes of Polygonatum cyrtonema Hua was elucidated by comparing its HIV infection inhibitory activity in MT-4 and CEM cells with that of other mannose-binding lectins (MBLs). "
5.	Carcinoma (Carcinomatosis) 11/29/2018 - "WITHDRAWN: Purification and characterizations of a new mannose specific lectin from Bangladeshi cultivated sword bean with antiproliferative activities against Ehrlich ascites carcinoma cells in vivo in mice." 01/01/2009 - "Among 28 candidate genes, LMAN1/ERGIC53, a mannose-specific lectin mediating endoplasmatic reticulum (ER)-to-Golgi transit of glycosylated proteins, showed high mutation frequency in MSI-H colorectal cancer cell lines (52%; 12 of 23), carcinomas (45%; 72 of 161), and adenomas (40%; 8 of 20). "

Related Drugs and Biologics

1.	Lectins
2.	Mannose (D-Mannose)
3.	Proteins (Proteins, Gene)
4.	Polysaccharides (Glycans)
5.	Mannose Receptor
6.	Pattern Recognition Receptors
7.	Defensins
8.	N-Acetylneuraminic Acid (Sialic Acid)
9.	Lipopolysaccharide Receptors
10.	Complementary DNA (cDNA)

Related Therapies and Procedures

1.	Intravesical Administration