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Collectins (Collectin)

A class of C-type lectins that target the carbohydrate structures found on invading pathogens. Binding of collectins to microorganisms results in their agglutination and enhanced clearance. Collectins form trimers that may assemble into larger oligomers. Each collectin polypeptide chain consists of four regions: a relatively short N-terminal region, a collagen-like region, an alpha-helical coiled-coil region, and carbohydrate-binding region.
Also Known As:
Collectin; Collagenous Lectins; Lectins, Collagenous
Networked: 100 relevant articles (6 outcomes, 10 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Holmskov, Uffe: 5 articles (10/2014 - 08/2002)
2. Kuroki, Yoshio: 5 articles (09/2011 - 07/2003)
3. Madan, Taruna: 4 articles (11/2015 - 11/2007)
4. Hartshorn, K L: 4 articles (01/2007 - 08/2000)
5. Crouch, E: 4 articles (08/2001 - 02/2000)
6. Bendixen, Christian: 3 articles (10/2014 - 01/2003)
7. Nishitani, Chiaki: 3 articles (09/2011 - 08/2007)
8. Takahashi, Motoko: 3 articles (09/2011 - 08/2007)
9. Haczku, Angela: 3 articles (08/2010 - 04/2004)
10. Hartshorn, Kevan L: 3 articles (01/2010 - 08/2002)

Related Diseases

1. Inflammation
2. Infection
3. Chronic Obstructive Pulmonary Disease (COPD)
4. Hypersensitivity (Allergy)
5. Blister (Bulla)

Related Drugs and Biologics

1. Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)
2. Proteins (Proteins, Gene)
3. Mannose-Binding Lectin (Mannan-Binding Lectin)
4. mannose receptor (receptor, mannose)
5. Azithromycin (Zithromax)
6. Blood Proteins (Serum Proteins)
7. Complement System Proteins (Complement)
8. Collectins (Collectin)
9. Biological Markers (Surrogate Marker)
10. Galectins (Galectin)

Related Therapies and Procedures

1. Therapeutics