Ciguatera Poisoning (Ciguatera)

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132 relevant articles (8 outcomes, 7 trials/studies) found for this Disease

Description: Poisoning caused by ingestion of SEAFOOD containing microgram levels of CIGUATOXINS. The poisoning is characterized by gastrointestinal, neurological and cardiovascular disturbances.

Also Known As:

Ciguatera; Poisoning, Ciguatera; Ciguatera Poisonings; Poisonings, Ciguatera

Relationship Network

Disease Context: Research Results

Disorders of Environmental Origin

Poisoning: 36999

Food Poisoning: 545

Ciguatera Poisoning: 132

Related Diseases

1.	Poisoning
2.	Syndrome
3.	Food Poisoning
4.	Ciguatera Poisoning (Ciguatera)
5.	Neuroblastoma
10 Diseases and 72 more articles analyzed in the Research Interface, order at left...

Experts

1.	Brooks, Christopher B: 1 article (10/2008)
2.	Schwarz, Evan S: 1 article (10/2008)
3.	Mullins, Michael Eugene: 1 article (10/2008)
4.	Siddiqi, Ather: 1 article (03/2008)
5.	Wasay, Mohammad: 1 article (03/2008)
6.	Sarangzai, Amanullah: 1 article (03/2008)
7.	Kiernan, Matthew C: 1 article (03/2008)
8.	Nizami, Qamaruddin: 1 article (03/2008)
9.	Vucic, Steve: 1 article (03/2008)
10.	Higa, Nicole: 1 article (01/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Ciguatera Poisoning:

1.	Mannitol (Osmitrol)FDA LinkGeneric 03/01/1995 - "Although no definitive therapy is known, the most promising treatment for ciguatera is intravenous administration of mannitol" 01/01/1992 - "Intravenous mannitol was introduced as an effective treatment for ciguatera in 1988" 03/01/2005 - "It is suggested that intravenous mannitol may prove to be a useful treatment for mild to moderate ciguatera poisoning, and for patients who present late for treatment." 01/01/1992 - "Evaluation of the efficacy of mannitol in the treatment of ciguatera in French Polynesia]" 07/17/1989 - "We report here the results of a pilot study to assess the efficacy of mannitol therapy in ciguatera poisoning" Get all the results and reference details, order at left...
2.	Amitriptyline (Elavil)FDA LinkGeneric 06/23/1984 - "Amitriptyline and ciguatera." 07/03/1986 - "Symptomatic improvement with amitriptyline in ciguatera fish poisoning." 01/01/1987 - "Treatment of ciguatera fish poisoning with amitriptyline and nifedipine." Get all the results and reference details, order at left...
3.	CiguatoxinsIBA 10/01/2007 - "In order to assess the ciguatera risk in two islands of French Polynesia, Tubuai (Australes) and Nuku Hiva (Marquesas), a study was carried out on both Gambierdiscus populations as well as on various fish species using the receptor-binding assay (RBA) to detect and quantify ciguatoxins" 01/01/1993 - "This study presents data on the evaluation of a laboratory ciguatera kit based on the solid phase immunobead assay (SPIA) for the detection of ciguatoxin in Hawaiian reef fish" 03/04/2004 - "A fully functionalized ABCDE ring moiety of ciguatoxin (CTX), the major causative agent of ciguatera poisoning, was synthesized for the first time" 03/01/2003 - "Ciguatoxins presence was assumed when symptomatology was typical of ciguatera in mouse and chick" 09/01/2002 - "4. In contrast, benthic species of dinoflagellates of the genus Gambierdiscus produce the ciguatoxins that are bioaccumulated into finfish to cause ciguatera" Get all the results and reference details, order at left...
4.	maitotoxinIBA 01/01/1991 - "Maitotoxin (MTX), a potent marine toxin involved in ciguatera poisoning, inhibited sea urchin egg fertilization in a dose-dependent manner with an IC50 of 7.5 x 10(-3) MU (mouse-unit)/ml. It did not affect male gametes fertilizing capabilities but provoked exocytosis in female gametes" 01/01/1988 - "Maitotoxin, one of the causative agents of ciguatera isolated from marine dinoflagellate, Gambierdiscus toxicus, induced severe pathomorphological changes in the stomach, heart and lymphoid tissues in mice and rats" 07/01/2005 - "The first is the use of maitotoxin, a marine toxin of ciguatera fish poisoning, which enables the incubation period to be reduced to 6 h when applied to the microplate 15 min prior to the end of the incubation" 01/01/1998 - "Maitotoxin (MTX), a water soluble polyether obtained from the marine dinoflagellate Gambierdiscus toxicus is one of the entities responsible for Ciguatera, a form of seafood poisoning" 02/28/2006 - "Maitotoxin (MTX) is known as one of the most potent marine toxins involved in Ciguatera poisoning, but intracellular signaling pathways caused by MTX was not fully understood" Get all the results and reference details, order at left...
5.	Okadaic AcidIBA 01/01/1998 - "Analysis of the culture extract using high-performance liquid chromatography and liquid chromatography-mass spectrometry indicated the production of okadaic acid, a toxic polyether linked with the human diseases, diarrhetic shellfish poisoning and ciguatera fish poisoning." 01/01/1994 - "Recent studies have also focused on the development of chemical methods, i.e., TLC and HPLC, for the detection and quantification of ciguatera-related toxins (okadaic acid and ciguatoxin and its analogs)" 11/01/1993 - "2. Other toxins, including okadaic acid and maitotoxin, have no proven role in causing human illness associated with ciguatera" 03/01/1995 - "Polyether marine toxins are responsible for the seafood intoxication phenomena known as neurotoxic shellfish poisoning (due to brevetoxins), ciguatera (due to ciguatoxin), and diarrheic shellfish poisoning (due to okadaic acid)" 02/01/2005 - "INTRODUCTION: Ciguatera poisoning is a clinical syndrome associated to consumption of marine fish with toxins as ciguatoxin, maitotoxin, scariotoxin, palytoxin and okadaic acid, produced by dinoflagellates present in seas with coral reefs" Get all the results and reference details, order at left...
6.	gambierolIBA 05/01/2005 - "Here, we have evaluated the effect of gambierol, one of the possible ciguatera toxins, on the voltage-gated ion currents in taste cells" 12/01/2003 - "Pathological effects on mice by gambierol, possibly one of the ciguatera toxins." 12/01/2003 - "Gambierol was isolated from Gambierdiscus toxicus, which causes ciguatera fish poisoning" 09/01/2006 - "Ciguatoxins (CTXs) and gambierol represent the two major causative agents of ciguatera intoxication, which include taste alterations (dysgeusiae)" 05/01/2005 - "In conclusion, unlike other toxins involved in ciguatera, such as ciguatoxins, which affect the functioning of voltage-gated sodium channels, the preferred molecular target of gambierol is the voltage-gated potassium channel, at least in taste cells" Get all the results and reference details, order at left...
7.	AcidsIBA 01/01/2001 - "Studies on ciguatera fish poisoning led to clarification of the absolute stereochemistry of ciguatoxin, gambierol, gambieric acids, and maitotoxin" Get all the results and reference details, order at left...
8.	suralIBA 01/01/1991 - "Fifteen cases of acute ciguatera poisoning were subjected to electrical studies on the sural and common peroneal nerves" Get all the results and reference details, order at left...
9.	Sodium Channels (Sodium Channel)IBA 12/01/2006 - "Ciguatera is a global disease caused by the consumption of certain warm-water fish that have accumulated orally effective levels of sodium channel activator toxins (ciguatoxins) through the marine food chain" 01/01/2001 - "Ciguatera is a global disease caused by the consumption of certain warm-water fish (ciguateric fish) that have accumulated orally effective levels of sodium channel activator toxins (ciguatoxins) through the marine food chain" 11/01/1993 - "1. Ciguatera is a disease caused by sodium channel activator toxins and results from the consumption of warm water fish contaminated by the ciguatoxin class of polyether toxins" 01/01/1993 - "Recent advances in toxin pharmacology have identified ciguatoxin as a sodium channel agonist and have begun to address other aspects of ciguatera on the molecular level" 11/01/2005 - "Ability of some plant extracts, traditionally used to treat ciguatera fish poisoning, to prevent the in vitro neurotoxicity produced by sodium channel activators." Get all the results and reference details, order at left...
10.	Tetrodotoxin (Tetradotoxin)IBA 12/13/2005 - "The clinical findings are described and likely represent ciguatera and tetrodotoxin poisonings" 04/01/2005 - "Tetrodotoxin poisoning and paralytic shellfish poisoning are less common but have a higher fatality rate than ciguatera" 11/01/1998 - "The tally of the toxins known up to date in Mexican waters includes: neurotoxin shellfish poisoning (NSP), paralytic shellfish poisoning (PSP), amnesic shellfish poisoning (ASP), tetrodotoxin (TTX) or puffer fish poisoning, ciguatera fish poisoning (CFP) and diarrhetic shellfish poisoning (DSP)" 04/01/1991 - "It appears in a variety of forms: poisoning, ciguatera, tetrodotoxin and scombroid poisoning" 04/01/2005 - "Three main clinical syndromes of marine poisoning have important neurological symptoms-ciguatera, tetrodotoxin poisoning, and paralytic shellfish poisoning" Get all the results and reference details, order at left...
69 Drugs and Important Bio-Agents and 130 more articles analyzed in the Research Interface, order at left...

Therapies and Procedures

1.	Baths 01/01/1993 - "Studies on ciguatera victims in which their hands were immersed in water baths ranging from 0 degree C to 50 degrees C, suggest the paradoxical sensory discomfort experienced is, most likely, a result of an exaggerated and intense nerve depolarization occurring in peripheral small A-delta myelinated and in particular, C-polymodal nociceptor fibers" Get all the results and reference details, order at left...
2.	Therapeutics 02/01/2000 - "Ion channel toxins and therapeutics: from cone snail venoms to ciguatera." Get all the results and reference details, order at left...
3.	Palliative Care (Palliative Medicine) 01/01/2005 - "No specific antidote exists to date, and it is only by symptomatic or palliative treatments that ciguatera is currently treated." Get all the results and reference details, order at left...
4.	Microspheres (Microsphere) 01/01/1992 - "The presence or absence of ciguatera-related toxins is determined by binding the toxins to a membrane attached to a plastic strip and exposing the toxin ladened membrane to a monoclonal antibody-colored latex bead complex which has a high specificity for ciguatera-related toxins" Get all the results and reference details, order at left...
5.	Lasers (Laser) 04/01/1996 - "Ciguatoxin-1b, the major toxin involved in ciguatera fish poisoning, and D-mannitol were examined on frog nodes of Ranvier using confocal laser scanning microscopy and conventional current- and voltage-clamp techniques" Get all the results and reference details, order at left...
5 Therapies and Procedures and 5 more articles analyzed in the Research Interface, order at left...

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