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ADP-ribosyl Cyclase

A membrane-bound or cytosolic enzyme that catalyzes the synthesis of CYCLIC ADP-RIBOSE (cADPR) from nicotinamide adenine dinucleotide (NAD). This enzyme generally catalyzes the hydrolysis of cADPR to ADP-RIBOSE, as well, and sometimes the synthesis of cyclic ADP-ribose 2' phosphate (2'-P-cADPR) from NADP.
Also Known As:
2'-P-ADPR Cyclase; 2'-Phospho-adenosine Diphosphate Ribose Cyclase; ADPR Cyclase; Adenosine Diphosphate Ribose Cyclase; Cyclic ADP-ribose Hydrolase; cADPR Hydrolase; 2' P ADPR Cyclase; 2' Phospho adenosine Diphosphate Ribose Cyclase; ADP ribosyl Cyclase; ADP-ribose Hydrolase, Cyclic; Cyclase, 2'-P-ADPR; Cyclase, ADP Ribose; Cyclase, ADP-ribosyl; Cyclase, ADPR; Cyclic ADP ribose Hydrolase; Hydrolase, Cyclic ADP-ribose; Hydrolase, cADPR; Ribose Cyclase, ADP; ADP Ribose Cyclase
Networked: 38 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Kim, Uh-Hyun: 5 articles (01/2019 - 08/2003)
2. Hashii, Minako: 4 articles (07/2007 - 06/2003)
3. Higashida, Haruhiro: 4 articles (07/2007 - 06/2003)
4. Noda, Mami: 4 articles (07/2007 - 06/2003)
5. Yokoyama, Shigeru: 4 articles (07/2007 - 06/2003)
6. Salmina, A B: 3 articles (01/2013 - 05/2009)
7. Gul, Rukhsana: 3 articles (02/2009 - 07/2008)
8. Kim, Seon-Young: 3 articles (02/2009 - 07/2008)
9. Jin, Duo: 3 articles (07/2007 - 09/2006)
10. Zhang, Jia-Sheng: 3 articles (03/2007 - 06/2003)

Related Diseases

1. Neuroblastoma
2. Neoplasms (Cancer)
3. Type 2 Diabetes Mellitus (MODY)
4. AIDS-Related Complex (ARC)
5. Ischemia

Related Drugs and Biologics

1. ADP-ribosyl Cyclase
2. Cyclic ADP-Ribose (cADPR)
3. NAD+ Nucleosidase (NAD(P) Nucleosidase)
4. Autoantibodies
5. GTP-Binding Proteins (G-Protein)
6. NAD (NADH)
7. Enzymes
8. Angiotensin II
9. Phospholipase C gamma
10. Phosphatidylinositol 3-Kinases (PI 3 Kinase)

Related Therapies and Procedures

1. Immunotherapy
2. Coronary Artery Bypass (Coronary Artery Bypass Surgery)