|1.||Chen, Jin: 5 articles (01/2011 - 10/2002)|
|2.||Pasquale, Elena B: 3 articles (10/2013 - 08/2010)|
|3.||Groves, Jay T: 3 articles (07/2013 - 03/2010)|
|4.||Mohammed, Kamal A: 3 articles (01/2013 - 11/2006)|
|5.||Nasreen, Najmunnisa: 3 articles (01/2013 - 11/2006)|
|6.||Brantley-Sieders, Dana M: 3 articles (01/2011 - 11/2005)|
|7.||Augstein, Antje: 2 articles (12/2014 - 10/2013)|
|8.||Strasser, Ruth H: 2 articles (12/2014 - 10/2013)|
|9.||Ende, Georg: 2 articles (12/2014 - 10/2013)|
|10.||Weinert, Sönke: 2 articles (12/2014 - 10/2013)|
04/29/2010 - "In this study, we show that HIC1 is a direct transcriptional repressor of the gene encoding ephrin-A1, a cell surface ligand implicated in the pathogenesis of epithelial cancers. "
04/24/2014 - "We identified ADAM12 (A disintegrin and metalloproteinase 12) as an EphA1-binding partner by yeast two-hybrid screening and found that ADAM12 enhanced ephrin-A1 cleavage in response to transforming growth factor-β1 in primary tumors. "
04/24/2014 - "Overexpression of ephrin-A1 has been implicated in tumor progression and poor prognosis. "
11/01/2013 - "We also found that ephrin-A1 was overexpressed in 3LL tumors, a highly metastatic tumor, in mice and TNFα, an authentic positive regulator of ephrin-A1, was not elevated in the tumors, whereas S100A8 was. "
01/01/2013 - "The effectiveness of targeted delivery of let-7a miR encapsulated ephrin-A1 conjugated LNP (miR-ephrin-A1-LNP) was determined on MPM and NSCLC tumor growth in vitro. "
|2.||Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
06/01/2012 - "Higher expression of EphA2 and ephrin-A1 is related to favorable clinicopathological features in pathological stage I non-small cell lung carcinoma."
01/01/2012 - "Expression of S100A4, ephrin-A1 and osteopontin in non-small cell lung cancer."
01/01/2012 - "The aim of this study was to investigate S100A4-mediated stimulation of ephrin-A1 and osteopontin in non-small cell lung cancer (NSCLC) cell lines, and to characterize the expression of these biomarkers in primary tumor tissue from NSCLC patients. "
01/01/2013 - "In a previously published report we characterized the expression of the metastasis-associated proteins S100A4, osteopontin (OPN) and ephrin-A1 in a prospectively collected panel of non-small cell lung cancer (NSCLC) tumors. "
04/01/2007 - "In this study, we demonstrated that expression of ephrin-A1 was dramatically down-regulated in glioma cell lines and in primary gliomas compared to the matched normal tissues. "
04/01/2007 - "These results suggested that ephrin-A1 serves as a critical negative regulator in the tumorigenesis of gliomas by down-regulating EphA2 and FAK, which may provide potential valuable targets for therapeutic intervention."
04/01/2007 - "EphA2, a receptor for ephrin-A1 and an oncoprotein, was greatly decreased in ephrin-A1-transfected glioma cells. "
04/01/2007 - "Forced expression of ephrin-A1 attenuated cell migration, cell proliferation, and adhesion-independent growth in human glioma U251 cells. "
04/01/2007 - "Ephrin-A1 is a negative regulator in glioma through down-regulation of EphA2 and FAK."
|4.||Psoriasis (Pustulosis Palmaris et Plantaris)
|5.||Lung Neoplasms (Lung Cancer)
01/01/2013 - "Targeted delivery of let-7a microRNA encapsulated ephrin-A1 conjugated liposomal nanoparticles inhibit tumor growth in lung cancer."
01/01/2013 - "In this study, to enhance the delivery of miR, the miRs were encapsulated in the DOTAP (N-[1-(2.3-dioleoyloxy)propyl]-N,N,N-trimethyl ammonium)/Cholesterol/DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[cyanur(polyethylene glycol)-2000])-PEG (polyethylene glycol)-cyanur liposomal nanoparticles (LNP) and ephrin-A1 was conjugated on the surface of LNP to target receptor EphA2 on lung cancer cells. "
|3.||Biological Markers (Surrogate Marker)
|4.||Polyethylene Glycols (Polyethylene Glycol)
|6.||Quaternary Ammonium Compounds (Ammonium)
|7.||1,2- dioleoyloxy- 3- (trimethylammonium)propane
|10.||Messenger RNA (mRNA)
|1.||Heterologous Transplantation (Xenotransplantation)
|2.||Photochemotherapy (Photodynamic Therapy)