|1.||Chen, Jin: 5 articles (02/2015 - 01/2004)|
|2.||Pasquale, Elena B: 5 articles (01/2015 - 02/2006)|
|3.||Debinski, Waldemar: 4 articles (12/2014 - 12/2008)|
|4.||Lackmann, Martin: 3 articles (12/2012 - 06/2005)|
|5.||Boyd, Andrew W: 3 articles (05/2010 - 01/2006)|
|6.||Xie, Dong: 2 articles (01/2013 - 02/2010)|
|7.||Li, Jing-Jing: 2 articles (01/2013 - 02/2010)|
|8.||Scott, Andrew M: 2 articles (12/2012 - 02/2012)|
|9.||Janes, Peter W: 2 articles (12/2012 - 09/2008)|
|10.||Genander, Maria: 2 articles (03/2012 - 10/2010)|
06/01/2012 - "This review is an attempt to summarize the data available on these Ephs/Ephrins' biological functions which contribute to the onset of aggressive cancers. "
06/01/2012 - "In fact, the role of Ephs and Ephrins in cancer progression has been demonstrated for many of the family members and they, surprisingly, have both tumor promoter and suppressor functions in different cellular contexts. "
03/01/2012 - "Eph and ephrins in epithelial stem cell niches and cancer."
11/17/2010 - "Of Ephs and ephrins: companies target guidance molecules in cancer."
01/01/2010 - "Here, we attempt to redress this imbalance and provide an 'ephrin-centric' discussion of the expression and function of ephrins in cancer."
|2.||Hepatocellular Carcinoma (Hepatoma)
02/01/2010 - "However, the role of Eph/Ephrins in hepatocellular carcinoma (HCC) has been rarely investigated. "
01/01/2015 - "Recent studies using clinical samples reported that the overexpression of Ephs and ephrins in some tumors such as hepatocellular carcinoma positively correlated with both malignancy of tumors and the poor prognosis of cancer patients. "
08/26/2013 - "Erythropoietin-producing hepatocellular carcinoma receptors (Ephs) and their ligands Ephrins can affect axon growth. "
04/01/2009 - "Erythropoietin-producing hepatocellular carcinoma (Eph)-family receptors recognize ligands, namely, ephrins, anchored to the membrane of apposing cells, and they mediate cell-cell contact-dependent events. "
11/26/2003 - "The A-class of the erythropoietin-producing hepatocellular carcinoma cell-derived (EphA) tyrosine kinase receptors and their ligands, the A-ephrins, play critical roles in the specification of topographic axon projection maps during development. "
|3.||Neoplasm Metastasis (Metastasis)
05/01/2010 - "An interesting observation emerging from these studies is the role for Ephs and ephrins in critical aspects of cell adhesion, migration and positioning, and a crucial role in tumor progression and metastasis. "
06/01/2012 - "I will also provide an overview of the factors which could explain the functional differences demonstrated by Ephs and Ephrins at different stages of tumor progression and whose elucidation is warranted for any future therapeutic targeting of this signaling pathway in cancer metastasis."
12/01/2010 - "Upregulation and de novo expression of ephrins in osteosarcomas are involved in oncogenic signalling and thus might stimulate osteosarcoma metastasis."
09/01/2005 - "Some of them belonged to some important signal pathways related with cell proliferation and metastasis, such as DDK1, ILK, MMP-1 and COL11A1 in Wnt/beta-catenin signal pathway, ILK in ILK signal pathway, EpHB2 in Eph-Ephrins signal pathway, ROCK2 in RhoA signal pathway, RANBP1 in RanGTPase signal pathway, and RBBP1 in RB/RBBP1 signal pathway. "
03/01/2010 - "Eph receptors and ephrins have been shown to affect the growth, migration and invasion of cancer cells in culture as well as tumour growth, invasiveness, angiogenesis and metastasis in vivo. "
01/01/2010 - "Many highly expressed transcripts in eEPCs are haematopoietic specific (RUNX1, WAS, LYN) with links to immunity and inflammation (TLRs, CD14, HLAs), whereas many transcripts involved in vascular development and angiogenesis-related signalling pathways (Tie2, eNOS, Ephrins) are highly expressed in OECs. "
04/14/2005 - "Although ephrins can be induced by bacterial LPS in vitro, whether they are involved in inflammation in vivo is unknown. "
01/01/2013 - "Ephs and ephrins resurface in inflammation, immunity, and atherosclerosis."
06/01/2006 - "In this review, we analyze our recent study on the expression of erythropoietin-producing hepatocellular (Eph) receptor kinases and their ligands, ephrins, in LPS-induced systemic inflammation. "
07/01/2007 - "Recent evidence suggests that Ephs and ephrins may also be involved in pathological angiogenesis, in particular, the neovascularization of tumors. "
10/01/2005 - "Vascular endothelial growth factor (VEGF) and other morphogens, such as angiopoietins and ephrins have been shown to be critically involved in the formation of new blood vessels during both developmental and pathological angiogenesis as evidenced by genetic studies in mice. "
|3.||EphA1 Receptor (Eph Receptor)
|6.||Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
|7.||Messenger RNA (mRNA)
|8.||Eph Family Receptors (Eph Receptors)
|10.||Proteins (Proteins, Gene)