|1.||Croce, Carlo M: 193 articles (12/2015 - 11/2002)|
|2.||Calin, George A: 146 articles (01/2016 - 07/2005)|
|3.||Zhang, Wei: 85 articles (12/2015 - 11/2008)|
|4.||Volinia, Stefano: 73 articles (03/2015 - 08/2005)|
|5.||Negrini, Massimo: 61 articles (11/2015 - 11/2002)|
|6.||Chen, Xi: 59 articles (01/2016 - 06/2008)|
|7.||Liu, Chang-Gong: 57 articles (01/2015 - 06/2004)|
|8.||Li, Jun: 55 articles (01/2016 - 01/2010)|
|9.||Seki, Naohiko: 52 articles (02/2016 - 07/2009)|
|10.||Thum, Thomas: 52 articles (12/2015 - 07/2007)|
01/01/2013 - "In contrast to current cancer medicines, miRNA-based therapies function by subtle repression of gene expression on a large number of oncogenic factors, and therefore are anticipated to be highly efficacious. "
12/01/2011 - "In contrast to current cancer medicines, miRNA-based therapies function by subtle repression of gene expression on a yet large number of oncogenic factors and are, therefore, anticipated to be highly efficacious. "
09/01/2011 - "Furthermore, clustering has proven elemental in microRNA expression profiling, which demonstrates enormous promise in the areas of cancer diagnosis and treatment, gene function identification, therapy development and drug testing, and genetic regulatory network inference. "
01/01/2015 - "Modulation of miRNA expression levels has been proven to increase the efficacy of genotoxic drugs in various preclinical cancer studies. "
08/01/2014 - "Researchers have reported that miRNAs can repress the expression of important cancer-related genes and might be helpful in the diagnosis and treatment of cancer. "
08/03/2010 - "Overall, we report a general strategy for examining the contributions of individual host miRNAs in viral infection and provide evidence that these molecules confer broad inhibitory potential against multiple viruses."
07/01/2015 - "Upon infection with NDV, DF-1 cells constitutively expressing the NP miRNA construct had improved cell survival up to 48 h post infection (h.p.i) and decreased viral yield up to 24 h.p.i. These results suggest that overexpression of the NP miRNA in cells and perhaps live animal may provide resistance to NDV."
01/01/2015 - "Areas under the receiver operation characteristic curve of the six miRNAs distinguishing immune tolerance and clearance of chronic HBV infection were 99.4%, 98.4%, 96.7%, 100%, 100%, and 99.6%. "
05/01/2013 - "Association of polymorphism in MicroRNA 219-1 with clearance of hepatitis B virus infection."
01/01/2011 - "Comprehensive knowledge about the related miRNAs during SGIV infection is helpful for understanding the infection and the pathogenic mechanisms. "
|3.||Breast Neoplasms (Breast Cancer)
09/01/2014 - "The assessment of core biopsy miRNA profiles and receptor-based subtypes may identify new signaling pathways for improved breast cancer classification. "
03/01/2010 - "Using a novel approach to extract miRNAs from the circulation followed by real-time quantitative polymerase chain reaction analysis, levels of a panel of 7 candidate miRNAs were quantified in tissue and blood specimens of 148 patients with breast cancer and 44 age-matched and disease free control individuals. "
02/10/2015 - "All these analysis results provided us a comprehensive view of the function of differential expression miRNAs related to drug resistance of breast cancer and may be helpful for the further study. "
01/01/2015 - "We investigated a panel of five miRNAs in the sera of two independent cohorts of breast cancer patients and disease-free controls. "
01/01/2014 - "Using microarray-based technology, we have performed a microRNA expression analysis in 71 primary breast tumors from patients that either remained disease-free at 5 years post-surgery (group A) or developed early (group B) or late (group C) recurrence. "
|4.||Lung Neoplasms (Lung Cancer)
01/01/2012 - "Better understanding of miRNA dysregulation may allow for improved biomonitoring and treatment regimens for lung cancer."
03/15/2008 - "These findings provide direct evidence that let-7 acts as a tumor suppressor gene in the lung and indicate that this miRNA may be useful as a novel therapeutic agent in lung cancer."
04/01/2014 - "Studying the role of miRNAs in lung cancer development and its relationship with diagnostic and prognostic parameters might help to improve the sensitivity of diagnosis and the efficacy of lung cancer treatment. "
11/01/2013 - "The three miRNAs used in combination produced the area under receiver operating characteristic curve at 0.847, which helped distinguish lung cancer from healthy smokers with 69.4% sensitivity and 78.3% specificity. "
01/01/2013 - "This review discusses the use of circulatory miRNAs that have been able to discriminate lung cancer patients from disease free controls. "
02/01/2012 - "Determination of miRNA expression levels may help to identify patients with an increased risk for severe inflammation."
12/01/2015 - "Studies have identified miRNAs involved in all three phases of wound healing including inflammation, proliferation, and remodeling. "
11/15/2015 - "This study provides the first evidence of a distinct profile of miRNAs associated with LECs during inflammation. "
11/01/2015 - "Studies using microarray and miRNA profiling may provide information about how DPCP induces inflammation in human skin at different times. "
11/01/2015 - "The present study aimed to explore whether miRNAs play a role in the steroid resistance of UC by regulating gene expression of the inflammation signal pathway. "
|2.||Biological Markers (Surrogate Marker)
|3.||Messenger RNA (mRNA)
|4.||RNA (Ribonucleic Acid)
|6.||Proteins (Proteins, Gene)
|2.||Drug Therapy (Chemotherapy)
|3.||Heterologous Transplantation (Xenotransplantation)