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Mastocytoma

A solid tumor consisting of a dense infiltration of MAST CELLS. It is generally benign.
Also Known As:
Benign Mastocytoma; Extracutaneous Mastocytoma; Mastocytoma, Extracutaneous; Extracutaneous Mastocytomas; Mastocytomas, Extracutaneous; Mastocytoma, Benign
Networked: 1092 relevant articles (25 outcomes, 67 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
2. Lymphoma (Lymphomas)
3. Melanoma (Melanoma, Malignant)
4. Experimental Melanoma
5. Atopic Dermatitis (Atopic Eczema)

Experts

1. Willmann, Michael: 8 articles (03/2018 - 02/2007)
2. Valent, Peter: 7 articles (03/2018 - 02/2007)
3. Ichikawa, Atsushi: 7 articles (04/2014 - 05/2003)
4. Zyad, Abdelmajid: 6 articles (10/2021 - 09/2006)
5. Hadzijusufovic, Emir: 6 articles (03/2018 - 10/2007)
6. Gleixner, Karoline V: 6 articles (01/2014 - 02/2007)
7. Pickl, Winfried F: 6 articles (01/2014 - 02/2007)
8. Kitani, Seiichi: 6 articles (05/2011 - 12/2002)
9. Peter, Barbara: 5 articles (03/2018 - 11/2008)
10. Fuhrmann, Herbert: 5 articles (08/2012 - 12/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Mastocytoma:
1. Interleukin-2 (IL2)IBA
2. Interleukin-12 (IL 12)IBA
01/01/2021 - "Using one of these mAbs, MM12A1.6, that strongly inhibited IFN-γ production and LPS-induced septic shock after viral infection, we demonstrate the critical role played by IL-12 in the rejection of male skin graft by female C57BL/6 syngeneic recipients and in the clearance of an immunogenic mastocytoma tumor variant by DBA/2 mice, but not in a parent to F1 immune aggression model nor in MOG-induced EAE, which was clearly prevented by anti-p40 mAb C17.8. Given this selective inhibition of IL-12, these mAbs provide new options for reassessing IL-12 function in vivo."
03/01/1999 - "In B16 melanoma and P815 mastocytoma models, antitumor efficacy of IL-12 protein therapy appeared to be slightly higher than that of IL-12 gene therapy; however, the protein therapy protocol in this comparative study resulted in a high level of mortality of mice. "
10/15/2005 - "Importantly, use of B7.1-CD40-engrafted PMV containing IL-2 and IL-12 as a vaccine in DBA/2J mice induced protection against challenge with syngeneic tumor cells (P815 mammary mastocytoma), and regression of established tumors. "
01/01/2012 - "Reduction of IL-12 production and expression of TLR9 in P815 mastocytoma cells by Per a 7 suggests that this major cockroach allergen might contribute to the development of cockroach allergy."
06/01/1999 - "The same effect of IL-12 was obtained with peptide P1A, which is a major tumor-specific antigen of mastocytoma P815 and is encoded by a gene that is specifically activated in tumors."
3. Histamine (Histamine Dihydrochloride)FDA Link
4. Adenosine Triphosphate (ATP)IBA
5. Isoantigens (Alloantigen)IBA
6. AntigensIBA
7. Peptides (Polypeptides)IBA
8. DNA (Deoxyribonucleic Acid)IBA
9. LeukotrienesIBA
10. VaccinesIBA

Therapies and Procedures

1. Therapeutics
2. Immunotherapy
3. Intralesional Injections
4. Oral Administration
5. Phototherapy (Light Therapy)