HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

RNA-Induced Silencing Complex

A multicomponent, ribonucleoprotein complex that cleaves specific mRNAs (RNA, MESSENGER) which are targeted for degradation by homologous dsRNAs (RNA, DOUBLE-STRANDED) during the process of RNA INTERFERENCE. It includes siRNA (RNA, SMALL INTERFERING) that is generated from the specific dsRNA.
Also Known As:
RISC Multicomponent Nuclease; Complex, RNA-Induced Silencing; Multicomponent Nuclease, RISC; Nuclease, RISC Multicomponent; RNA Induced Silencing Complex; Silencing Complex, RNA-Induced
Networked: 29 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Lee, Sug Hyung: 2 articles (05/2013 - 04/2010)
2. Yoo, Nam Jin: 2 articles (05/2013 - 04/2010)
3. Milane, Lara: 1 article (12/2015)
4. Amiji, Mansoor M: 1 article (12/2015)
5. Suresh, Megha: 1 article (12/2015)
6. Singh, Amit: 1 article (12/2015)
7. Mattheolabakis, George: 1 article (12/2015)
8. Shepherd, Danielle L: 1 article (12/2015)
9. Croston, Tara L: 1 article (12/2015)
10. Martinez, Ivan: 1 article (12/2015)

Related Diseases

1. Infection
2. Urinary Bladder Neoplasms (Bladder Cancer)
3. Neoplasms (Cancer)
4. Wounds and Injuries (Trauma)
5. Skin Neoplasms (Skin Cancer)

Related Drugs and Biologics

1. Messenger RNA (mRNA)
2. Ribonucleases (Ribonuclease)
3. MicroRNAs (MicroRNA)
4. Small Interfering RNA (siRNA)
5. Proteins (Proteins, Gene)
6. RNA (Ribonucleic Acid)
7. Ribonuclease III (RNase III)
8. Collagen Type I (Type I Collagen)
9. Viral RNA
10. Double-Stranded RNA (RNA, Double Stranded)