|1.||Wadhwa, Renu: 5 articles (12/2014 - 05/2007)|
|2.||Barboro, Paola: 5 articles (10/2014 - 06/2009)|
|3.||Balbi, Cecilia: 5 articles (10/2014 - 06/2009)|
|4.||Ferrari, Nicoletta: 5 articles (10/2014 - 06/2009)|
|5.||Kaul, Sunil C: 4 articles (12/2014 - 05/2013)|
|6.||Gao, Ran: 3 articles (12/2014 - 05/2013)|
|7.||Chen, Lih-Chyang: 3 articles (01/2014 - 06/2008)|
|8.||Chang, Yu-Sun: 3 articles (01/2014 - 06/2008)|
|9.||Liang, Ying: 3 articles (01/2014 - 06/2008)|
|10.||Chang, Kai-Ping: 3 articles (01/2014 - 06/2008)|
|1.||Prostatic Neoplasms (Prostate Cancer)
05/19/2009 - "Heterogeneous nuclear ribonucleoprotein K: altered pattern of expression associated with diagnosis and prognosis of prostate cancer."
03/15/2009 - "We show here that hnRNP-K is a novel inhibitor of AR mRNA translation that regulates androgen-responsive gene expression and prostate cancer cell proliferation. "
06/15/2009 - "Novel antivascular efficacy of metronomic docetaxel therapy in prostate cancer: hnRNP K as a player."
05/01/2014 - "Prostate cancer: prognostic significance of the association of heterogeneous nuclear ribonucleoprotein K and androgen receptor expression."
03/04/2004 - "The combination of upregulated activity in the growth-promoting PI3K/Akt pathway, suppression of Nmi and overexpression of hnRNP-K and c-myc proteins may explain why the prostate cancer cells were found to be more resistant to the growth inhibitory effects of INFgamma."
10/01/2014 - "Herein, we provide a brief overview of the multifunctional roles of hnRNP K and discuss clinical studies that have demonstrated its involvement in cancer development and progression."
07/01/2013 - "Taken together, this study establishes that hnRNP K plays an antiapoptotic role in HCC cell lines, independent of p53 status, via the maintenance of high levels of endogenous caspase inhibitors, and also identifies hnRNP K as a possible therapeutic marker for cancer treatment. "
03/03/2009 - "A study by Enge et al. in this issue of Cancer Cell shows that the ability of MDM2 to target hnRNP K for degradation contributes to the decision to induce apoptosis rather than cell-cycle arrest."
10/12/2015 - "Together, these data implicate hnRNP K in the development of hematological disorders and suggest hnRNP K acts as a tumor suppressor. "
01/01/2015 - "Additionally, our results indicated that the cytoplasmic distribution of hnRNP K induced by TGF-β stimulus mainly contributed to TGF-β-triggered tumor cell invasion in RCC cells. "
09/01/2013 - "Further studies showed that hnRNP K suppresses apoptosis of virus-infected cells, resulting in increased cell survival during VSV infection. "
09/01/2013 - "To decipher the role of hnRNP K in VSV infection, we conducted studies which suggest that the protein is required for VSV spreading. "
05/04/2015 - "Total levels of hnRNP K expression were unaffected by DENV-2 or JUNV infection. "
01/01/2015 - "Functional ablation of cytoplasmic hnRNP-K by a nanoscale intracellular antibody markedly attenuated bacterial entry and infection but not binding. "
10/01/2008 - "During EV71 infection, hnRNP K was enriched in the cytoplasm where virus replication occurs, whereas hnRNP K was localized in the nucleus in mock-infected cells. "
|4.||Colorectal Neoplasms (Colorectal Cancer)
09/01/2012 - "Expression of HSP27 and hnRNP K were investigated by immunohistochemistry (IHC) in a series of tissue microarrays containing 175 primary colorectal cancers and their corresponding normal mucosa samples and matched with clinicopathological features and patient survival. "
10/09/2006 - "In normal colon hnRNP K was exclusively nuclear whereas in colorectal cancer the protein localised both in the cytoplasm and the nucleus. "
10/09/2006 - "Heterogeneous nuclear ribonucleoprotein K is over expressed, aberrantly localised and is associated with poor prognosis in colorectal cancer."
05/01/2010 - "HnRNP K and PDI marked response to chemotherapy to human colorectal cancer cells."
10/09/2006 - "In this study comparing normal colon to colorectal cancer by proteomics, hnRNP K was identified as being overexpressed in this type of cancer. "
|5.||Neoplasm Metastasis (Metastasis)
01/01/2014 - "The aim of the present study was to determine the role of matrix metalloproteinase (MMP) in hnRNP K-mediated metastasis in NPC. "
01/01/2015 - "Particularly, the rate of cytoplasmic localization of hnRNP K in primary RCC with distant metastasis was significantly higher than that in RCC without metastasis. "
07/01/2014 - "CNBP overexpression caused increase of cell death and suppression of cell metastasis through its induction of G-quadruplex formation in the promoter of hnRNP K resulting in hnRNP K down-regulation. "
01/01/2014 - "However, the mechanisms underlying hnRNP K-mediated metastasis is unclear. "
05/24/2013 - "Our results demonstrated that the hnRNP-K is a potential target for metastasis therapy."
|2.||Heterogeneous-Nuclear Ribonucleoprotein K
|3.||Proteins (Proteins, Gene)
|4.||Messenger RNA (mRNA)
|5.||Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
|6.||RNA (Ribonucleic Acid)
|7.||Biological Markers (Surrogate Marker)
|8.||Androgen Receptors (Androgen Receptor)
|9.||HSP27 Heat-Shock Proteins
|1.||Heterologous Transplantation (Xenotransplantation)
|2.||Drug Therapy (Chemotherapy)