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Heterogeneous-Nuclear Ribonucleoprotein K

A heterogeneous-nuclear ribonucleoprotein found in the CELL NUCLEUS and the CYTOPLASM. Heterogeneous-nuclear ribonucleoprotein K has been implicated in the regulation of gene expression at nearly all levels: GENETIC TRANSCRIPTION; mRNA processing (RNA PROCESSING, POST-TRANSCRIPTIONAL), mRNA transport, mRNA stability, and translation (TRANSLATION, GENETIC). The hnRNP protein has a strong affinity for polypyrimidine-rich RNA and for single-stranded polypyrimidine-rich DNA. Multiple hnRNP K protein isoforms exist due to alternative splicing and display different nucleic-acid-binding properties.
Also Known As:
Heterogeneous Nuclear Ribonucleoprotein Particle K Protein; dC-Stretch-Binding Protein; hnRNP K; hnRNP K Protein; Heterogeneous Nuclear Ribonucleoprotein K; Ribonucleoprotein K, Heterogeneous-Nuclear; dC Stretch Binding Protein
Networked: 81 relevant articles (1 outcomes, 14 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Wadhwa, Renu: 5 articles (12/2014 - 05/2007)
2. Barboro, Paola: 5 articles (10/2014 - 06/2009)
3. Balbi, Cecilia: 5 articles (10/2014 - 06/2009)
4. Ferrari, Nicoletta: 5 articles (10/2014 - 06/2009)
5. Kaul, Sunil C: 4 articles (12/2014 - 05/2013)
6. Gao, Ran: 3 articles (12/2014 - 05/2013)
7. Chen, Lih-Chyang: 3 articles (01/2014 - 06/2008)
8. Chang, Yu-Sun: 3 articles (01/2014 - 06/2008)
9. Liang, Ying: 3 articles (01/2014 - 06/2008)
10. Chang, Kai-Ping: 3 articles (01/2014 - 06/2008)

Related Diseases

1. Prostatic Neoplasms (Prostate Cancer)
2. Neoplasms (Cancer)
3. Infection
4. Colorectal Neoplasms (Colorectal Cancer)
5. Neoplasm Metastasis (Metastasis)

Related Drugs and Biologics

1. docetaxel (Taxotere)
2. Heterogeneous-Nuclear Ribonucleoprotein K
3. Proteins (Proteins, Gene)
4. Messenger RNA (mRNA)
5. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
6. RNA (Ribonucleic Acid)
7. Biological Markers (Surrogate Marker)
8. Androgen Receptors (Androgen Receptor)
9. HSP27 Heat-Shock Proteins
10. Matrix Metalloproteinases

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Drug Therapy (Chemotherapy)