|2.||Deafness (Deaf Mutism)
|3.||Vertigo (Positional Vertigo)
|4.||Hearing Loss (Hearing Impairment)
|1.||Guan, Min-Xin: 44 articles (11/2015 - 01/2004)|
|2.||Smith, Richard J H: 36 articles (08/2015 - 05/2002)|
|3.||Dai, Pu: 35 articles (10/2015 - 05/2005)|
|4.||Avraham, Karen B: 25 articles (09/2014 - 03/2002)|
|5.||Van Camp, Guy: 25 articles (01/2013 - 05/2002)|
|6.||Cremers, Cor W R J: 25 articles (03/2011 - 01/2002)|
|7.||Hickson, Louise: 24 articles (11/2015 - 07/2003)|
|8.||Han, Dongyi: 23 articles (01/2013 - 09/2003)|
|9.||Usami, Shin-ichi: 22 articles (06/2014 - 05/2002)|
|10.||Zhu, Yi: 19 articles (11/2015 - 06/2005)|
|1.||Dexamethasone (Maxidex)FDA LinkGeneric
04/01/1996 - "The initial response to dexamethasone perfusion plus intravenous dexamethasone has been very good, with very little risk of further hearing loss, and it holds great promise for the future."
06/01/2012 - "Local dexamethasone provides partial protection against this hearing loss, but the degree and extent of protection are less compared to previous studies with unprimed animals."
01/01/2015 - "In one trial, dexamethasone reduced the likelihood of hearing loss at four to 10 weeks post discharge (RR 0.41, 95% CI 0.17 to 0.98; RD -0.25, 95% CI -0.48 to -0.01; one study, 59 participants, low-quality evidence). "
09/01/1989 - "Based on statistically combined results of the three most recent trials, there is evidence that dexamethasone reduces the risk of bilateral moderate or more severe hearing loss (risk difference, -9%; 95% confidence limits, -15% and -3%). "
10/01/2015 - "Dexamethasone was shown to reduce hearing loss."
|2.||Cisplatin (Platino)FDA LinkGeneric
09/01/2015 - "Intratympanic DXM has demonstrated protective effects against cisplatin-induced hearing loss in a few animal studies and one clinical trial. "
03/01/2013 - "Transtympanic administration of KR-22332 in a rat model was protective against cisplatin-induced hearing loss, as determined by click-evoked auditory brainstem response (p<0.01). "
11/28/1999 - "The findings of studies from this laboratory are summarized to compare the efficacy of four chemoprotective agents against the effects of cisplatin-induced hearing loss and biochemical damage in the rat cochlea. "
02/20/2007 - "The presence of both alleles of 105Val-GSTP1 offered protection against cisplatin-induced hearing impairment. "
01/01/2015 - "Further functional studies showed that locally administrated single-dose DEX-NPs effectively preserved outer hair cells in guinea pigs after cisplatin insult and thus significantly attenuated hearing loss at 4 kHz and 8 kHz frequencies when compared to the control of free DEX formulation. "
07/01/2013 - "High dose Intravenous steroids are a safe and effective treatment in sudden sensori-neural hearing loss. "
01/01/1998 - "The evaluation of efficacy of various treatment demonstrates a slight improvement of the hearing loss using steroids associated to vasodilatators, even if no significant difference is found between the different therapies. "
11/01/2012 - "Foremost in the minds of clinicians is the immune suppression and anti-inflammatory functions of steroids because of their efficacy for autoimmune hearing loss. "
11/01/1995 - "Until recently the site of the lesion has been debatable and the efficacy of steroids commonly prescribed for this type of hearing loss has been said to be doubtful. "
02/01/1994 - "Hearing impairment in 35 cases (55%) was cured or improved by medical treatment including steroids. "
|4.||Gentamicins (Gentamicin)FDA LinkGeneric
02/01/2007 - "The amount of postprocedure hearing loss was significantly greater in the gentamicin group (p = 0.03). "
02/01/2004 - "The amount of postprocedure hearing loss was significantly greater in the gentamicin treatment group (P =.006). "
06/01/2014 - "Here, a combination of nutrients previously shown to reduce oxidative stress in the hair cells and attenuate hearing loss after other insults was evaluated for potential protection against gentamicin-induced ototoxicity. "
01/01/2004 - "After the withdrawol of gentamicin, the vestibular pathologic symptoms but not the hearing loss had improved, docummented by the persistance of the audiometric decay in the acute frequencies. "
12/01/2015 - "Six trials reported consistently measured ototoxicity outcomes in neonates treated with gentamicin, and the pooled estimate for hearing loss was 3% (95% CI 0-7%). "
|5.||Prednisolone (Predate)FDA LinkGeneric
08/27/1993 - "Under high-dosage glucocorticoid treatment (initially 1,000 mg/d prednisolone intravenously for 3 days, then 100 mg/d orally in decreasing doses down to 10 mg daily) the ocular signs improved, but the bilateral hearing impairment persisted. "
06/01/2015 - "At 9 years and 0 months old, 9 years and 2 months old, and 10 years and 0 months old, he had experienced acute exacerbations of hearing loss, each of which was successfully rescued by intravenous or oral prednisolone within 2 weeks. "
01/01/2012 - "She had been treated with 300 mg of tocopherol for scleroderma since 2007 and treated with 9 mg of prednisolone (PSL) for autoimmune hearing loss since 2010. "
06/01/2009 - "Early use of prednisolone can prevent hearing loss and can also be useful in treating the other vasculitic manifestations."
12/01/2000 - "This combination therapy enabled the successful tapering of prednisolone without recurrence of hearing loss. "
|6.||Adrenal Cortex Hormones (Corticosteroids)IBA
07/01/1999 - "Overall injection of intratympanic corticosteroids for the treatment of hearing loss in inner ear disorders appears to be both safe and highly effective for certain disorders. "
07/01/2009 - "The efficacy of adjuvant corticosteroids varied between high- and low-income countries suggesting greater mortality reduction in high-income countries (RR 0.74, 95% CI 0.52-1.05) than in low-income countries (RR 0.87, 95% CI 0.72-1.05) and a beneficial effect on severe hearing loss in high-income countries (RR 0.32, 95% CI 0.18-0.57), whereas, sparse data in low-income countries (RR 1.04, 95% CI 0.66-1.63). "
09/01/1993 - "However, corticosteroids significantly reduced the frequency of bilateral, moderate, or greater hearing loss. "
01/01/2013 - " analysis for study quality showed no effect of corticosteroids on severe hearing loss in high-quality studies.Corticosteroid"
09/01/2010 - "However, both experimental studies and clinical trials investigating the effect of corticosteroids on hearing loss have generated conflicting results. "
|7.||Glycerol (Glycerine)FDA LinkGeneric
03/01/1977 - "The glycerol test also has been reported as being effective for the same purpose but only in Meniere patients with fluctuating hearing loss (Klockhoff & Lindblom, 1966). "
07/01/2000 - "Her left hearing loss was improved during the glycerol test. "
09/01/2005 - "There was no difference in the degree of hearing loss induced by saline or by fluids with viscosities up to 1,000 times greater than that of water (glycerol). "
09/01/2005 - "To evaluate the contribution of each of these factors to hearing loss, various volumes of saline, whole blood, or glycerol were applied to the open middle ear cavity of guinea pigs for short periods of time and auditory function was evaluated by recording the threshold of auditory nerve-brainstem evoked responses. "
01/01/2002 - "The glycerol test was positive only in 4 patients with unilateral MD and moderate hearing loss. "
06/01/2009 - "Antioxidants administered before sound exposure show promise in mitigating hearing loss in industrial and combat situations. "
09/01/2010 - "We suggest that this model be applied to future studies investigating the effects of antioxidants on hearing loss."
10/01/2007 - "The objective of this paper is to highlight some of the important studies published over the past several years that have further contributed to our understanding of the mechanism of antioxidants in attenuating hearing loss. "
06/01/2015 - "Evaluation of serum antioxidants in age-related hearing loss."
01/01/2015 - "Nevertheless, certain antioxidants and non-specific NOX inhibitors diminish hearing loss in animal models. "
07/01/2012 - "In addition, international standards for grading and comparing ototoxicity are essential to the success of prospective pediatric trials aimed at reducing platinum-induced hearing loss. "
11/01/2014 - "Patients were excluded due to congenital hearing loss (n = 1) and insufficient data for calculating the platinum dose (n = 24) or for assessing ototoxicity (n = 135). "
05/01/2008 - "Hearing loss does not correlate with the platinum (Pt) concentration found in the inner ear. "
02/01/2008 - "The difference in hearing loss could not be explained by different cumulative exposures of the platinum agents. "
10/01/2004 - "Platinum compound-related ototoxicity in children: long-term follow-up reveals continuous worsening of hearing loss."
|10.||Carboplatin (JM8)FDA LinkGeneric
02/01/2002 - "The finding of hearing loss was significantly greater in the patients treated with CDDP (86%) vs. those treated with CBDCA (33%). "
03/01/2001 - "Delayed STS was effective in protecting against carboplatin-induced hearing loss. "
12/01/2007 - "The present study showed that carboplatin at higher doses induced hearing loss and increased NO levels in the cochlea of rats. "
05/01/2004 - "The aim of the study was to evaluate the time response of carboplatin-induced hearing loss and oxidative injury to the cochlea of the rat. "
09/01/2003 - "The study aim was to evaluate carboplatin-induced hearing loss and oxidative injury to the central auditory system (inferior colliculus) of the rat. "
|1.||Hearing Aids (Hearing Aid)
10/01/2004 - "Though traditional hearing aids remain the mainstay of treatment for most uncorrectable hearing loss, partially implantable devices may offer solutions when standard therapy fails."
12/01/2010 - "Adult aural rehabilitation for hearing loss in a public health care facility, even without optimal hearing aid fittings, was effective in providing positive perceived outcomes comparable to similar studies in developed countries. "
08/01/2007 - "According to previous studies on the matter, our data suggest that identification of hearing loss at early age associated with early hearing aid fitting, and enrollment in early intervention within the first 12 months of age, may help to obtain good results in the receptive language skills performance. "
02/01/2001 - "Findings were consistent with previous studies showing positive outcomes for newer technologies but also showed that two subjective factors, prefitting hearing aid expectations and acceptance of hearing loss, significantly influenced hearing aid outcome."
03/01/1979 - "This study sought to determine if a high-pass hearing aid can provide increased improvement in word recognition and consonant discrimination over that of a conventional high frequency emphasis hearing aid in listeners with hearing loss limited to frequencies above 1 000 Hz. Word and consonant discrimination were assessed in quiet and in the presence of 12 talker speech babble for 10 subjects under three listening conditions: (1) unaided; (2) wearing a conventional high frequency emphasis hearing aid, and (3) wearing an experimental high-pass instrument. "
|2.||Cochlear Implants (Cochlear Implant)
11/01/2015 - "In one patient, despite good results, the device had to be replaced with a conventional cochlear implant because of Tinnelec-independent increase in hearing loss on the contralateral ear. "
07/01/2014 - "Although it has been established that bilateral cochlear implants (CIs) offer additional speech perception and localization benefits to many children with severe to profound hearing loss, whether these improved perceptual abilities facilitate significantly better language development has not yet been clearly established. "
01/01/2007 - "These findings suggest that cochlear implants offer some significant benefits to children with hearing impairment in terms of prosody and voice outcomes."
04/01/2013 - "Cochlear implant is an effective treatment for severe to profound hearing loss in children, contributing to a hearing performance and an appropriate language acquisition, currently comparable to normal hearing children. "
12/01/2009 - "Using acoustic simulations of a cochlear implant and hearing loss, it is shown that localization performance can be improved by up to 14 degrees rms error relative to 48 degrees rms error for broadband noise by artificially introducing ILD cues in the low frequencies. "
08/01/2012 - "Cochlear implantation was successful at rehabilitating the hearing loss with the child able to continue mainstream education, with her academic performance and speech discrimination both showing marked improvement. "
05/01/2015 - "Four children underwent bilateral cochlear implantation for congenital hearing loss, with all showing good results. "
05/01/2014 - "Cochlear implantation can be beneficial in patients with profound hearing loss associated with Paget's disease. "
11/01/2013 - "Cochlear implantation in children with an asymmetrical hearing loss is now becoming more recognized as an appropriate and beneficial treatment option. "
07/01/2012 - "There is a significant improvement in auditory performance of infants with prelingually profound hearing loss within the first year after cochlear implantation. "
|4.||Drug Therapy (Chemotherapy)
12/01/2002 - "In contrast, very little information is available about the efficacy of intravenous drug therapy for ISSNHL with the beginning of treatment later than four weeks after the onset of hearing loss. "
03/01/2014 - "However, the improvement in distant failure-free rate (D-FFR) was insignificant, and more hearing impairment occurred due to chemotherapy. "
09/01/2009 - "The criteria described in this study were inadequate to identify hearing loss following chemotherapy, requiring additional information for physicians to better understand the hearing losses and their implications for the quality of life of patients."
06/01/2015 - "[Local drug therapy for inner ear hearing loss]."
03/01/2014 - "However, it should also be noted that hearing impairment significantly increased due to chemotherapy, L-FFR reached a plateau in the 3DRT era, and it is worrisome that the result for T4 remained unsatisfactory. "
|5.||Stapes Surgery (Stapedectomy)
12/01/2004 - "The hearing impairment can be improved by stapes surgery."
12/01/2004 - "Hearing impairment improved after stapedectomy. "
10/01/1965 - "Discrimination scores at levels above the maximum audiometer output as a prognostic aid in preoperative study of stapedectomy candidates with severe hearing loss."
01/01/2014 - "Revision operations after previous stapes surgery for persisting hearing loss."
01/01/2012 - "The author examined a 52-year-old man who had undergone bilateral stapedectomy because of hearing loss; his rheumatologist referred him to the Salivary Gland Center (New York City) because of a complaint of dry mouth. "