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Aristolochic Acids

Nitro-phenanthrenes occurring in ARISTOLOCHIACEAE and other plants. They derive from stephanine (APORPHINES) by oxidative ring cleavage. The nitro group is a reactive alkylator (ALKYLATING AGENTS) that binds to biological macromolecules. Ingestion by humans is associated with nephropathy (NEPHRITIS). There is no relationship to the similar named aristolochene (SESQUITERPENES).
Networked: 31 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Vanherweghem, Jean-Louis: 4 articles (03/2008 - 02/2002)
2. Nortier, Joëlle L: 3 articles (12/2015 - 02/2002)
3. Nortier, Joëlle: 3 articles (05/2015 - 03/2002)
4. Grollman, Arthur P: 3 articles (09/2010 - 07/2007)
5. Antoine, Marie-Hélène: 2 articles (12/2015 - 05/2015)
6. Husson, Cécile: 2 articles (12/2015 - 05/2015)
7. Pavlović, Nikola M: 2 articles (06/2013 - 04/2013)
8. Lo, Tsai-Chang: 2 articles (01/2013 - 04/2011)
9. Yang, Hsiao-Yu: 2 articles (01/2013 - 04/2011)
10. Wang, Jung-Der: 2 articles (01/2013 - 04/2011)

Related Diseases

1. Poisoning
2. Chronic Kidney Failure (Chronic Renal Failure)
3. Fibrosis (Cirrhosis)
4. Neoplasms (Cancer)
5. Carcinoma (Carcinomatosis)

Related Drugs and Biologics

1. aristolochic acid I (aristolochic acid)
2. Carcinogens
3. Tin
4. DNA (Deoxyribonucleic Acid)
5. Citrinin
6. Alkaloids
7. ochratoxin A
8. serum P-component (CIt)

Related Therapies and Procedures

1. Transplantation (Transplant Recipients)
2. Injections