Adaptor Protein Complex 1

A clathrin adaptor protein complex primarily involved in clathrin-related transport at the TRANS-GOLGI NETWORK.

Also Known As:

Adaptor Protein Complex 1 (AP-1); Adaptor-Related Protein Complex 1; Golgi Adaptor Protein 1; Adaptor Related Protein Complex 1; Clathrin Adaptor Protein Complex 1; Clathrin Assembly Protein Complex 1

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Chen, Sini: 1 article (01/2022)
2.	Fan, Xiaohong: 1 article (01/2022)
3.	Gao, Yueyi: 1 article (01/2022)
4.	Shen, Youfeng: 1 article (01/2022)
5.	Xu, Jian: 1 article (01/2022)
6.	Ye, Xin: 1 article (01/2022)
7.	Yi, Yuanxue: 1 article (01/2022)
8.	Zhang, Qiufang: 1 article (01/2022)
9.	Ahmed, Zubair M: 1 article (01/2021)
10.	Brigatti, Karlla W: 1 article (01/2021)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2022 - "System Analysis of Adaptor-Related Protein Complex 1 Subunit Mu 2 (AP1M2) on Malignant Tumors: A Pan-Cancer Analysis." 10/01/2023 - "Here, we investigated the role of adaptor-related protein complex 1 subunit sigma 1 (AP1S1), a component of adaptor protein complex-1, in the regulation of EGF receptor (EGFR) intracellular trafficking during cancer cell progression. "
2.	Neurodevelopmental Disorders 01/01/2021 - "Here, we report two bi-allelic (c.737C>A [p.Pro246His] and c.1105A>G [p.Met369Val]) and eight de novo heterozygous variants (c.44G>A [p.Arg15Gln], c.103C>T [p.Arg35Trp], c.104G>A [p.Arg35Gln], c.229delC [p.Gln77Lys∗11], c.399_400del [p.Glu133Aspfs∗37], c.747G>T [p.Gln249His], c.928-2A>C [p.?], and c.2459C>G [p.Pro820Arg]) in AP1G1, encoding gamma-1 subunit of adaptor-related protein complex 1 (AP1γ1), associated with a neurodevelopmental disorder (NDD) characterized by mild to severe ID, epilepsy, and developmental delay in eleven families from different ethnicities. "
3.	Lipoma (Lipomata) 01/01/2019 - "Moreover, among the 14 dysregulated genes with potential miRNA regulations identified, src kinase associated phosphoprotein 2 (SKAP2), adaptor related protein complex 1 sigma 2 subunit (AP1S2), PHD finger protein 21A (PHF21A), lipoma preferred partner (LPP), and transcription factor AP-2 alpha (TFAP2A) showed similar expression patterns in OA FLS and OA synovial tissue datasets in Gene Expression Omnibus database. "
4.	Infections 01/01/2016 - "Here, we identified adaptor protein complex 1 sigma 3 subunit (AP1S3) as a dependency factor for the efficient HCV infection in hepatoma cells. "
5.	Hepatocellular Carcinoma (Hepatoma) 01/01/2016 - "Here, we identified adaptor protein complex 1 sigma 3 subunit (AP1S3) as a dependency factor for the efficient HCV infection in hepatoma cells. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	ErbB Receptors (EGF Receptor)
3.	Transcription Factor AP-2
4.	MicroRNAs (MicroRNA)
5.	Sigma Factor
6.	src kinase associated phosphoprotein 2