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Clathrin Light Chains

The light chain subunits of clathrin.

Also Known As:

Clathrin Light Chain; Light Chains, Clathrin

Networked: 15 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Vesicular Transport Proteins: 1
      - Clathrin: 704
        Clathrin Light Chains: 15
        S pombe Clc1 protein

Experts

1.	Jiang, Hongbing: 1 article (01/2020)
2.	Leung, Christian: 1 article (01/2020)
3.	Sandoval Del Prado, Luis Enrique: 1 article (01/2020)
4.	Wang, David: 1 article (01/2020)
5.	Huang, Youhua: 1 article (10/2019)
6.	Li, Qiang: 1 article (10/2019)
7.	Liu, Jiaxin: 1 article (10/2019)
8.	Ni, Songwei: 1 article (10/2019)
9.	Qin, Qiwei: 1 article (10/2019)
10.	Wang, Liqun: 1 article (10/2019)

Related Diseases

1.	Hepatocellular Carcinoma (Hepatoma) 12/01/2023 - "The present study aimed to elucidate the role of clathrin light chain A (CLTA) in sEV uptake in hepatocellular carcinoma (HCC). " 01/01/2023 - "This study aimed to elucidate the functions and mechanisms of hepatocellular carcinoma (HCC) derived sEV-clathrin light chain A (CLTA) in remodelling microvascular niche. " 12/01/2023 - "Clathrin light chain A facilitates small extracellular vesicle uptake to promote hepatocellular carcinoma progression." 01/01/2023 - "Clathrin light chain A-enriched small extracellular vesicles remodel microvascular niche to induce hepatocellular carcinoma metastasis."
2.	Squamous Cell Carcinoma (Epidermoid Carcinoma) 02/01/1992 - "This study demonstrates that the EGF receptor, partially purified from A431 epidermoid carcinoma cells, catalyzes the phosphorylation of one of the two clathrin light chains, clathrin light chain a (LCa). "
3.	Alzheimer Disease (Alzheimer's Disease) 01/01/1994 - "Involvement of clathrin light chains in the pathology of Alzheimer's disease." 01/01/1994 - "In the brains of the patients with Alzheimer's disease, distribution of clathrin was immunohistochemically investigated using four monoclonal antibodies against clathrin light chains, LCB.1, LCB.2, X-16 and CON.1, to study the involvement of clathrin in the pathology of Alzheimer's disease. "
4.	Neoplasms (Cancer) 01/01/2023 - "Here, we report a targeted delivery platform for cancer treatment using clathrin light chain (CLC)-conjugated drugs. " 01/01/2023 - "Clathrin light chain-conjugated drug delivery for cancer." 12/01/2007 - "Together with some previously well known deregulated proteins in CRC (beta-catenin, c-MYC, or p63), we found new potential markers preferentially expressed in CRC tumors: cytokeratin 13, calcineurin, CHK1, clathrin light chain, MAPK3, phospho-PTK2/focal adhesion kinase (Ser-910), and MDM2. " 01/01/2019 - "Further development of the solid tumor after the 2nd week following cancer cell inoculation, secretion of prolific tumor-derived factors as well as the presence of the increasing number of circulating cancer cells and extravasation processes further impose reorganization of the lung tissue [Actb, vimentin (Vim), clathrin light chain A (Clta)], altering additional metabolic pathways [annexin A5 (Anxa5), Rho GDP-dissociation inhibitor 2 (Arhgdib), complement 1 Q subcomponent-binding protein, mitochondrial (C1qbp), 14-3-3 protein zeta/delta (Ywhaz), peroxiredoxin-6 (Prdx6), chitinase-like protein 4 (Chi3l4), reticulocalbin-1 (Rcn1), EF-hand domain-containing protein D2 (Efhd2), calumenin (Calu)]. "
5.	Neoplasm Metastasis (Metastasis) 01/01/2023 - "Clathrin light chain A-enriched small extracellular vesicles remodel microvascular niche to induce hepatocellular carcinoma metastasis." 01/01/2019 - "Missing-in-metastasis protein promotes internalization of magnetic nanoparticles via association with clathrin light chain and Rab7."

Related Drugs and Biologics

1.	Clathrin Light Chains
2.	Clathrin
3.	Monoclonal Antibodies
4.	ErbB Receptors (EGF Receptor)
5.	Proteins (Proteins, Gene)
6.	Clathrin Heavy Chains
7.	Phosphatidylinositols (Phosphatidylinositol)
8.	rho Guanine Nucleotide Dissociation Inhibitor beta
9.	Sorting Nexins
10.	Keratin-13 (Keratin 13)