Type I Activin Receptors

One of the two types of ACTIVIN RECEPTORS or activin receptor-like kinases (ALK'S). There are several type I activin receptors. The major active ones are ALK-2 (ActR-IA) and ALK-4 (ActR-IB).

Also Known As:

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Jonas, C: 1 article (10/2000)
2.	Krebs, R: 1 article (10/2000)
3.	Röher, H D: 1 article (10/2000)
4.	Schulte, K M: 1 article (10/2000)

Related Diseases

1.

Goiter 10/01/2000 - "Semi-quantitative RT-PCR revealed a significant 2.5-fold decrease of mRNA for alk4-1 type I activin receptors in goiter as compared to normal thyroid (p < 0.05), whereas expression of the type II receptor actRII was unchanged. " 10/01/2000 - "Analysis in native tissues from 12 normal thyroids, 16 goiters, and 5 Graves thyroids demonstrated mRNA expression of the activin subunit betaA, TGFbeta-receptor type I and II, activin receptors type I receptors alk2 and alk4, and activin type II receptors actRII and actRIIb. "

Related Drugs and Biologics

1.	Activins (Activin)
2.	Transforming Growth Factor beta (TGF-beta)
3.	Messenger RNA (mRNA)