Seminal Plasma Proteins

Proteins found in SEMEN. Major seminal plasma proteins are secretory proteins from the male sex accessory glands, such as the SEMINAL VESICLES and the PROSTATE. They include the seminal vesicle-specific antigen, an ejaculate clotting protein; and the PROSTATE-SPECIFIC ANTIGEN, a protease and an esterase.

Networked: 25 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Agarwal, Ashok: 3 articles (04/2021 - 11/2019)
2.	Panner Selvam, Manesh Kumar: 3 articles (04/2021 - 11/2019)
3.	Bernstein, Jonathan A: 3 articles (09/2011 - 01/2003)
4.	Diamandis, Eleftherios P: 2 articles (01/2019 - 02/2012)
5.	Gordetsky, Jennifer: 2 articles (11/2012 - 07/2011)
6.	Izumi, Koji: 2 articles (11/2012 - 07/2011)
7.	Miyamoto, Hiroshi: 2 articles (11/2012 - 07/2011)
8.	Yao, Jorge L: 2 articles (11/2012 - 07/2011)
9.	Zheng, Yichun: 2 articles (11/2012 - 07/2011)
10.	Dias, Tânia R: 1 article (04/2021)

Related Diseases

1.	Varicocele 04/01/2021 - "A total of 47 seminal plasma proteins were differentially expressed in unilateral varicocele patients compared to fertile donors. " 01/01/2021 - "Proteomic Profiling of Seminal Plasma Proteins in Varicocele Patients." 11/01/2019 - "In varicocele-associated infertility, the contributory role of seminal plasma proteins specific to unilateral and bilateral varicocele is not clear. " 01/01/2021 - "The main objective of this study is to compare the seminal plasma proteome of healthy fertile men (control group) with varicocele patients in order to identify the differentially expressed seminal plasma proteins. " 01/01/2021 - "Aberrant expression of seminal plasma proteins serve as an indicator of sperm pathology in varicocele patients."
2.	Neoplasms (Cancer) 08/01/2007 - "Proteomic approach for purification of seminal plasma proteins involved in tumor proliferation." 01/01/2019 - "In this study, we investigated if seminal plasma proteins could increase diagnostic specificity of detecting primary prostate cancer and discriminate between high- and low-grade cancers. " 07/01/2011 - "Little is known about the role of semenogelins, seminal plasma proteins that play critical roles in semen clotting and subsequent liquefaction in the presence of zinc and prostate-specific antigen, in human malignancies. "
3.	Prostatic Neoplasms (Prostate Cancer) 12/18/2001 - "These results indicate that hK4 may have a role in the physiologic processing of seminal plasma proteins such as pro-PSA, as well as in the pathogenesis of prostate cancer through its activation of pro-uPA." 01/01/2019 - "In this study, we investigated if seminal plasma proteins could increase diagnostic specificity of detecting primary prostate cancer and discriminate between high- and low-grade cancers. "
4.	Shock 05/17/1996 - "The results presented here strongly suggest that seminal plasma proteins are adsorbed by a spermatozoal surface previously exposed to thermic shock. " 05/17/1996 - "Reversion of thermic-shock effect on ram spermatozoa by adsorption of seminal plasma proteins revealed by partition in aqueous two-phase systems." 05/17/1996 - "Centrifugal counter-current distribution (CCCD) in a dextran, Ficoll, poly(ethylene glycol) two-phase system was used to study the effect of seminal plasma proteins on the partition behaviour of ram spermatozoa exposed to thermal shock. "
5.	Infertility (Sterility) 01/01/2020 - "This panel of altered seminal plasma proteins associated with unexplained male factor infertility might have clinical relevance and may be useful in the diagnosis and prognosis of idiopathic infertility in in vitro fertilization. " 01/01/2020 - "To identify potential seminal plasma proteins to contribute to a new understanding of unexplained male factor infertility. " 01/01/2019 - "This review is focused on the role of seminal plasma proteins on various walks of fertilization process and thus, the possible exploitation of seminal plasma proteins for understanding the etiology of male related infertility issues. " 12/01/1987 - "These findings suggest that oligospermic men may have accelerated proteolysis of sperm or seminal plasma proteins that may contribute to subfertility." 11/01/2019 - "In varicocele-associated infertility, the contributory role of seminal plasma proteins specific to unilateral and bilateral varicocele is not clear. "

Related Drugs and Biologics

1.	Proteome
2.	Ethylene Glycol (Monoethylene Glycol)
3.	Ficoll
4.	Dextrans (Dextran)
5.	Proteins (Proteins, Gene)
6.	Immunoglobulin E (IgE)
7.	Retinoid X Receptors (Retinoid X Receptor)
8.	Prostate-Specific Antigen (Semenogelase)
9.	Cytokines
10.	Zinc

Related Therapies and Procedures

1.	Condoms (Condom)
2.	Prostatectomy (Retropubic Prostatectomy)