Autosomal Dominant Optic Atrophy (Dominant Optic Atrophy)
42
relevant articles (1 outcomes,
2 trials/studies)
found for this Disease
Description:
Dominant optic atrophy is a hereditary optic neuropathy causing decreased visual acuity, color vision deficits, a centrocecal scotoma, and optic nerve pallor (Hum. Genet. 1998; 102: 79-86). Mutations leading to this condition have been mapped to the OPA1 gene at chromosome 3q28-q29. OPA1 codes for a dynamin-related GTPase that localizes to mitochondria.
Also Known As:
Dominant Optic Atrophy; Optic Atrophy, Autosomal Dominant; Optic Atrophy Type 1; Optic Atrophy, Kjer Type; Dominant Optic Atrophies; Optic Atrophies, Dominant; Optic Atrophy, Dominant; Optic Atrophy, Hereditary, Autosomal Dominant
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Disease Context: Research Results