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beta Karyopherins (Importin-beta)

Nucleocytoplasmic transport molecules that bind to ALPHA KARYOPHERINS in the CYTOSOL and are involved in transport of molecules through the NUCLEAR PORE COMPLEX. Once inside the CELL NUCLEUS beta karyopherins interact with RAN GTP-BINDING PROTEIN and dissociate from alpha karyopherins. Beta karyopherins bound to RAN GTP-BINDING PROTEIN are then re-transported to the cytoplasm where hydrolysis of the GTP of RAN GTP-BINDING PROTEIN causes release of karyopherin beta.
Also Known As:
Importin-beta; Kap95 protein; Karyopherin beta; Karyopherin-beta Subunit; beta Importins; p92 nuclear protein; Importin beta; Importins, beta; Karyopherin beta Subunit; Karyopherins, beta; nuclear protein, p92; Karyopherin-beta
Networked: 13 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Yang, Xianbin: 1 article (01/2015)
2. Torres, Keila E: 1 article (01/2015)
3. Zhang, Pingyu: 1 article (01/2015)
4. Ma, Xiaoyan: 1 article (01/2015)
5. Pollock, Raphael E: 1 article (01/2015)
6. Lazar, Alexander J: 1 article (01/2015)
7. Ingram, Davis R: 1 article (01/2015)
8. Kopecky-Bromberg, Sarah A: 1 article (09/2007)
9. Yount, Boyd: 1 article (09/2007)
10. Heise, Mark: 1 article (09/2007)

Related Diseases

1. Neoplasms (Cancer)
2. Infection
3. Severe Acute Respiratory Syndrome
4. Nerve Sheath Neoplasms (Nerve Sheath Neoplasm)
5. T-Cell Leukemia (Leukemia, T Cell)

Related Drugs and Biologics

1. alpha Karyopherins
2. Nuclear Localization Signals (Nuclear Localization Signal)
3. Antigens
4. Parathyroid Hormone-Related Protein
5. Karyopherins (Importin)
6. Small Nuclear Ribonucleoproteins (snRNP)
7. rex Gene Products
8. Proteins (Proteins, Gene)
9. NADH Dehydrogenase
10. Hemoglobins (Hemoglobin)