|1.||Jans, David A: 8 articles (08/2015 - 07/2005)|
|2.||Loveland, Kate L: 4 articles (08/2014 - 09/2011)|
|3.||Neumann, Manuela: 4 articles (11/2012 - 08/2010)|
|4.||Mackenzie, Ian R A: 4 articles (11/2012 - 08/2010)|
|5.||Ahluwalia, Amrita: 3 articles (12/2014 - 02/2014)|
|6.||Leaner, Virna D: 3 articles (05/2014 - 04/2009)|
|7.||van der Watt, Pauline J: 3 articles (05/2014 - 04/2009)|
|8.||Engelman, Alan: 3 articles (10/2013 - 01/2010)|
|9.||Ansorge, Olaf: 3 articles (11/2012 - 09/2011)|
|10.||Dormann, Dorothee: 3 articles (11/2012 - 08/2010)|
05/01/2014 - "We previously showed that Kpnβ1, a nuclear importin protein, is overexpressed in cervical cancer and is critical for cervical cancer cell survival and proliferation, whereas non-cancer cells are less dependent on its expression. "
04/19/2012 - "Tumorigenesis and tumor progression are associated with dysfunction of the nuclear transport machinery at the level of import and export receptors (karyopherins). "
04/15/2009 - "Since these are all critical cellular functions, alterations in the expression of the Karyopherins may have an impact on the biology of cancer cells. "
05/15/2011 - "Importin subunit alpha-2 is identified as a potential biomarker for non-small cell lung cancer by integration of the cancer cell secretome and tissue transcriptome."
01/01/2016 - "Dysregulation of exportins (XPOs, nucleocytoplasmic transporters) associated with subcellular mislocalization of proteins has been reported for various human cancers. "
03/01/2015 - "Our results showed that while TGB1 self-interaction is needed for cell-to-cell movement, importin-α-mediated nucleolar targeting of TGB1 is an essential step in establishing the efficient systemic infection of the entire plant. "
01/01/2015 - "Knockdown of the host cellular protein transportin 3 attenuates prototype foamy virus infection."
01/01/2010 - "Lentiviruses, with the exception of FIV, display a requirement for transportin 3 in comparison to MLV and RSV, yielding an infection-based dependency ranking of SIV > HIV-1 > BIV and EIAV > MLV, RSV, and FIV. "
01/01/2010 - "Recent genome-wide screens have highlighted an important role for transportin 3 in human immunodeficiency virus type 1 (HIV-1) infection and preintegration complex (PIC) nuclear import. "
01/01/2009 - "Nuclear import of the HIV-1 reverse transcription complex (RTC) is critical for infection of non dividing cells, and importin 7 (imp7) has been implicated in this process. "
12/11/2009 - "Transport of hypoxia-inducible factor HIF-1alpha into the nucleus involves importins 4 and 7."
12/01/2015 - "In this study we evaluated the physiological activity of this importin α/β-inhibitor (Ivermectin) in the hypoxia response pathway. "
12/01/2015 - "The importin α/β-specific inhibitor Ivermectin affects HIF-dependent hypoxia response pathways."
02/15/2014 - "We examined in these cells 1) in vitro angiogenesis, 2) expression of VEGF and importin-α, 3) nuclear transport of hypoxia-inducible factor (HIF)-1α by importin-α, 4) binding of HIF-1α to the VEGF gene promoter, and 5) effects of importin-α silencing in YGEC and its upregulation in AGEC on angiogenesis and VEGF expression. "
12/01/2014 - "We focus on the time sequence and ultrastructural features of angiogenesis, hypoxia as a trigger, role of vascular endothelial growth factor signaling (VEGF), serum response factor, Cox2 and prostaglandins, nitric oxide, and importin. "
01/01/2014 - "We developed a new nuclear transport modifier (NTM) peptide, cell-penetrating cSN50.1, which targets nuclear transport shuttles importin α5 and importin β1, to analyze its effect in LPS-induced localized (acute lung injury) and systemic (lethal endotoxic shock) murine inflammation models. "
07/01/2011 - "To study whether alcohol and endotoxin induce inflammation, apoptosis, and expression of downstream genes TNF-α and caspase-3 through the nuclear transcription factor NF-κB, i.e., the IκB-NF-κB-importin α pathway. "
01/01/2008 - "Resistant strain-specific expression of genes implicated in innate immunity of invertebrates was identified, including hydrolytic enzymes such as cathepsin L, a cysteine proteinase involved in lysis of phagocytosed particles; metabolic enzymes such as ornithine decarboxylase, the rate-limiting enzyme in the production of polyamines, important in inflammation and infection processes, as well as scavenging damaging free radicals produced during production of reactive oxygen species; stress response genes such as HSP70; proteins involved in signalling, such as importin 7 and copine 1, cytoplasmic intermediate filament (IF) protein and transcription enzymes such as elongation factor 1alpha and EF-2. "
|5.||Pancreatic Neoplasms (Pancreatic Cancer)
|2.||Inosine Monophosphate (IMP)
|4.||Tumor Viral Antigens (Large T Antigen)
|5.||Caspase 3 (Caspase-3)
|6.||Capsid Proteins (Capsid Protein)
|7.||Transcription Factors (Transcription Factor)
|9.||Proteins (Proteins, Gene)
|10.||DNA (Deoxyribonucleic Acid)
|1.||Transplantation (Transplant Recipients)