Familial Amyloid Neuropathies (Familial Amyloid Polyneuropathy)

Inherited disorders of the peripheral nervous system associated with the deposition of AMYLOID in nerve tissue. The different clinical types based on symptoms correspond to the presence of a variety of mutations in several different proteins including transthyretin (PREALBUMIN); APOLIPOPROTEIN A-I; and GELSOLIN.
Also Known As:
Familial Amyloid Polyneuropathy; Amyloid Neuropathies, Familial; Amyloid Polyneuropathy, British Type; Amyloid Polyneuropathy, Iowa Type; Amyloid Polyneuropathy, Swiss Type; Appalachian Type Familial Amyloid Polyneuropathy; British Type Amyloid Polyneuropathy; Familial Amyloid Neuropathy, Andrade Type; Familial Amyloid Neuropathy, Finnish Type; Familial Amyloid Neuropathy, Portuguese Type; Familial Amyloid Polyneuropathy, Appalachian Type; Familial Amyloid Polyneuropathy, Jewish Type; Familial Amyloid Polyneuropathy, Type I; Familial Amyloid Polyneuropathy, Type II; Familial Amyloid Polyneuropathy, Type III; Familial Amyloid Polyneuropathy, Type IV; Familial Amyloid Polyneuropathy, Type V; Familial Amyloid Polyneuropathy, Type VI; Familial Portuguese Polyneuritic Amyloidosis; Finnish Type Familial Amyloid Neuropathy; Hereditary Neuropathic Amyloidosis; Iowa Type Amyloid Polyneuropathy; Jewish Type Familial Amyloid Polyneuropathy; Polyneuritic Amyloidosis, Portuguese; Portuguese Polyneuritic Amyloidosis; Portuguese Type Familial Amyloid Neuropathy; Swiss Type Amyloid Polyneuropathy; Type I Familial Amyloid Polyneuropathy; Type II Familial Amyloid Polyneuropathy; Type III Familial Amyloid Polyneuropathy; Type IV Familial Amyloid Polyneuropathy; Type V Familial Amyloid Polyneuropathy; Type VI Familial Amyloid Polyneuropathy; Amyloid Neuropathy, Familial; Amyloid Polyneuropathies, Familial; Amyloid Polyneuropathy, Familial; Amyloidoses, Hereditary Neuropathic; Amyloidoses, Portuguese Polyneuritic; Amyloidosis, Hereditary Neuropathic; Amyloidosis, Portuguese Polyneuritic; Familial Amyloid Neuropathy; Hereditary Neuropathic Amyloidoses; Neuropathic Amyloidoses, Hereditary; Neuropathic Amyloidosis, Hereditary; Neuropathies, Familial Amyloid; Neuropathy, Familial Amyloid; Polyneuritic Amyloidoses, Portuguese; Polyneuropathies, Familial Amyloid; Polyneuropathy, Familial Amyloid; Portuguese Polyneuritic Amyloidoses; Familial Amyloid Polyneuropathies
Networked: 446 relevant articles (16 outcomes, 30 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Polyneuropathies (Polyneuropathy)
2. Amyloidosis
3. Cardiomyopathies (Cardiomyopathy)
4. Orthostatic Hypotension (Postural Hypotension)
5. Neuralgia (Stump Neuralgia)


1. Ikeda, Shu-ichi: 21 articles (12/2013 - 11/2002)
2. Ando, Yukio: 19 articles (09/2014 - 11/2002)
3. Sekijima, Yoshiki: 14 articles (09/2015 - 03/2003)
4. Koike, Haruki: 12 articles (12/2013 - 11/2002)
5. Sobue, Gen: 12 articles (12/2013 - 11/2002)
6. Kelly, Jeffery W: 11 articles (12/2013 - 04/2002)
7. Ikeda, Shu-Ichi: 11 articles (09/2013 - 03/2003)
8. Conceição, Isabel: 9 articles (12/2015 - 06/2002)
9. Suhr, Ole B: 9 articles (01/2015 - 09/2002)
10. Planté-Bordeneuve, Violaine: 8 articles (11/2015 - 09/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Familial Amyloid Neuropathies:
1. Prealbumin (Transthyretin)IBA
2. Amyloid (Amyloid Fibrils)IBA
3. tafamidisIBA
4. Diflunisal (Dolobid)FDA Link
5. Dopamine beta-HydroxylaseIBA
6. 3-Iodobenzylguanidine (Iobenguane)IBA
7. Complementary DNA (cDNA)IBA
8. Small Interfering RNA (siRNA)IBA
9. Genetic Markers (Genetic Marker)IBA
10. gallium citrateIBA

Therapies and Procedures

1. Liver Transplantation
2. Transplants (Transplant)
3. Transplantation (Transplant Recipients)
4. Therapeutics
5. Sympathectomy (Sympathectomies)