CD98 Antigens

A heterodimeric protein that is a cell surface antigen associated with lymphocyte activation. The initial characterization of this protein revealed one identifiable heavy chain (ANTIGENS, CD98 HEAVY CHAIN) and an indeterminate smaller light chain. It is now known that a variety of light chain subunits (ANTIGENS, CD98 LIGHT CHAINS) can dimerize with the heavy chain. Depending upon its light chain composition a diverse array of functions can be found for this protein. Functions include: type L amino acid transport, type y+L amino acid transport and regulation of cellular fusion.
Also Known As:
Antigens, CD98; 4F2 Antigen; 4F2-antigen; CD98 Antigen; CD98 Transport Proteins; FRP-1 protein; H4F2 Antigen; Human 4F2 Antigen; Human 4F2 Cell-Surface Antigen; Human Lymphocyte Activation Antigen 4F2; 4F2 Antigen, Human; Antigen, CD98; FRP 1 protein; Fusion Regulatory Protein 1; Human 4F2 Cell Surface Antigen; Regulatory Protein-1, Fusion; Antigen 4F2; Fusion Regulatory Protein-1
Networked: 20 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results


1. Sharma-Walia, Neelam: 1 article (12/2008)
2. Chandran, Bala: 1 article (12/2008)
3. Varga, Laszlo: 1 article (12/2008)
4. Sadagopan, Sathish: 1 article (12/2008)
5. Veettil, Mohanan Valiya: 1 article (12/2008)
6. Raghu, Hari: 1 article (12/2008)
7. Wang, Fu-Zhang: 1 article (12/2008)
8. Bröer, S: 1 article (01/2001)
9. Coenen, H H: 1 article (01/2001)
10. Mühlensiepen, H: 1 article (01/2001)

Related Diseases

1. Neoplasms (Cancer)
2. Medullary Carcinoma
3. Crohn Disease (Crohn's Disease)
4. Carcinoma (Carcinomatosis)
5. Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)

Related Drugs and Biologics

1. Antigens
2. Transferrin Receptors (Transferrin Receptor)
3. Interleukin-2 Receptors (IL 2 Receptor)
4. DNA (Deoxyribonucleic Acid)
5. Amino Acid Transport Systems (Amino Acid Transporter)
6. Integrins
7. CD Antigens
8. Tyrosine (L-Tyrosine)
9. Membrane Glycoproteins (Membrane Glycoprotein)
10. Interleukin-2 (IL2)