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LDL-Receptor Related Protein 2

An LDL-RECEPTOR RELATED PROTEIN found in the neuroepithelium and in proximal tubular cells of the kidney. It is considered a multiligand receptor in that it binds to a variety of ligands with relatively high affinity and may function in mediating the uptake and lysosomal degradation of macromolecules such as: LIPOPROTEINS; ENDOPEPTIDASES; and PROTEASE INHIBITORS.
Also Known As:
Antigen GP 330, Nephritis; GP330 Antigen; Glycoprotein 330; Heyman's Nephritis Antigen GP330; Heymann Nephritis Antigen GP330; LRP-2; LRP-2 Receptor; Nephritis Antigen (GP330); Renal Glycoprotein GP330; GP330, Renal Glycoprotein; Glycoprotein GP330, Renal; LDL Receptor Related Protein 2; LRP 2; LRP 2 Receptor; Low Density Lipoprotein Receptor Related Protein 2; Low-Density Lipoprotein Receptor-Related Protein-2; Megalin
Networked: 181 relevant articles (4 outcomes, 13 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Saito, Akihiko: 12 articles (01/2014 - 08/2003)
2. Christensen, Erik I: 8 articles (06/2015 - 07/2004)
3. Gejyo, Fumitake: 8 articles (05/2012 - 08/2003)
4. Nielsen, Rikke: 7 articles (10/2014 - 07/2008)
5. Takeda, Tetsuro: 7 articles (05/2012 - 08/2003)
6. Carro, Eva: 6 articles (01/2015 - 11/2005)
7. Iino, Noriaki: 6 articles (05/2012 - 08/2003)
8. Kaseda, Ryohei: 6 articles (05/2012 - 04/2005)
9. Willnow, Thomas E: 6 articles (11/2010 - 02/2003)
10. Spuch, Carlos: 5 articles (01/2015 - 11/2005)

Related Diseases

1. Albuminuria
2. Alzheimer Disease (Alzheimer's Disease)
3. Neoplasms (Cancer)
4. Fibrosis (Cirrhosis)
5. Membranous Glomerulonephritis (Membranous Nephropathy)

Related Drugs and Biologics

1. intrinsic factor-cobalamin receptor
2. Small Interfering RNA (siRNA)
3. Insulin-Like Growth Factor I (IGF-1)
4. LDL-Receptor Related Protein 2
5. Glycoproteins (Glycoprotein)
6. Complementary DNA (cDNA)
7. Lipofuscin
8. Gentamicins (Gentamicin)
9. Cadmium
10. Antibodies

Related Therapies and Procedures

1. Tissue Therapy (Cell Therapy)
2. Thyroidectomy
3. Drug Therapy (Chemotherapy)