|1.||Yoshizawa, Nobuyuki: 4 articles (09/2010 - 01/2005)|
|2.||Oda, Takashi: 4 articles (09/2010 - 01/2005)|
|3.||Holdsworth, S R: 4 articles (06/2002 - 02/2000)|
|4.||Tipping, P G: 4 articles (06/2002 - 02/2000)|
|5.||Miura, Soichiro: 3 articles (09/2010 - 01/2005)|
|6.||Sugisaki, Tetsuzo: 3 articles (09/2010 - 01/2005)|
|7.||Yamakami, Kazuo: 3 articles (09/2010 - 01/2005)|
|8.||Holdsworth, Stephen R: 3 articles (03/2008 - 02/2002)|
|9.||Kitching, A R: 3 articles (06/2002 - 02/2000)|
|10.||Barabas, Arpad Zsigmond: 2 articles (11/2012 - 04/2006)|
|1.||Membranous Glomerulonephritis (Membranous Nephropathy)
03/01/1968 - "A single immunization with less than a milligram of a crude renal tubular preparation, probably containing less than 25 microg of the specific nephritogenic antigen, is effective in the induction of this form of chronic membranous glomerulonephritis. "
09/10/1994 - "It is apparent that significant progress has been made in the characterization of gp330 in the years that have elapsed since its initial identification as the nephritogenic antigen of Heymann nephritis. "
10/01/1987 - "Identification of a 400-kd protein in the brush borders of human kidney tubules that is similar to gp330, the nephritogenic antigen of rat Heymann nephritis."
10/01/1985 - "The results show that immunization with Fx1A produces a more severe form of Heymann nephritis than does gp 330, and that Fx1A contains at least one nephritogenic antigen in addition to gp 330."
01/01/1989 - "Furthermore, they suggest that this antigen may also be involved in the membranous glomerulonephritis of the rat in addition to the Heymann antigen."
03/01/2006 - "Nephritogenic antigen for acute poststreptococcal glomerulonephritis."
06/01/1997 - "Human nephritogenic antigen induces anti-glomerular basement membrane antibody glomerulonephritis in rats. "
04/01/1989 - "Early changes of experimental autoimmune glomerulonephritis induced with the bovine nephritogenic antigen from renal basement membranes were studied in inbred WKY/NCrj rats. "
04/01/1989 - "Early changes of rat experimental autoimmune glomerulonephritis induced with the nephritogenic antigen from bovine renal basement membranes."
10/01/1985 - "Antibody-induced redistribution of Heymann antigen on the surface of cultured glomerular visceral epithelial cells: possible role in the pathogenesis of Heymann glomerulonephritis."
04/01/1986 - "Investigation of the dose-effect relationship of the nephritogenic antigen in F344 and WKY rats revealed that the minimum dose required to induce nephritis in F344 and WKY rats was 10 micrograms and 3 micrograms respectively, and that the injection of more than a certain amount (i.e., 30 micrograms in F344, 10 micrograms in WKY) of the antigenic material induced almost the same severity of disease. "
06/01/1997 - "Purification and characterization of human nephritogenic antigen that induces anti-GBM nephritis in rats."
01/01/1990 - "Heymann's nephritis can be induced in rats by injection of antibodies (Ab) against the major nephritogenic antigen (Ag) (gp330). "
08/01/1989 - "The original actively-immunized anti-GBM nephritis was induced in inbred WKY/NCrj rats by injecting the nephritogenic antigen from bovine renal basement membranes. "
02/01/1983 - "The nephritogenic antigen of Heymann's nephritis (HN) was previously purified from tubular brush-border fractions of rat kidney and found to be a 330,000- mol-wt glycoprotein (gp330). "
07/01/2003 - "Cutaneous delayed-type hypersensitivity after subdermal challenge with the nephritogenic antigen was attenuated in the absence of BM cell-derived TNF but unaffected in WT-->TNF-/- chimeric mice. "
05/01/2000 - "Neither treatment altered the circulating antibody titer or cutaneous delayed type hypersensitivity to the nephritogenic antigen. "
02/01/2000 - "Circulating antibody (IL-10-/-, 1.05 +/- 0.16 OD units; IL-10+/+, 0.63 +/- 0.08 OD units) and cutaneous delayed-type hypersensitivity (skin swelling; IL-10-/-, 0.21 +/- 0.03 mm; IL-10+/+, 0.12 +/- 0.02 mm) to the nephritogenic antigen (sheep globulin) were also increased (both P < 0.05). "
03/01/2008 - "We examined the role of T-bet in the development of experimental crescentic glomerulonephritis, which is induced by Th1-predominant, delayed-type hypersensitivity-like responses directed against a nephritogenic antigen. "
02/01/2002 - "Humoral responses to the nephritogenic antigen were unaltered by deficiency of either GM-CSF or G-CSF, but glomerular T cell and macrophage numbers, as well as dermal delayed-type hypersensitivity to the nephritogenic antigen, were reduced in GM-CSF -/- mice. "
|5.||Anti-Glomerular Basement Membrane Disease (Goodpasture's Syndrome)
10/01/1987 - "These results suggest that this experimental model is similar to the experimental glomerulonephritis induced in rats by bovine nephritogenic antigen, and to human anti-glomerular basement membrane antibody-induced glomerulonephritis including Goodpasture's syndrome."
06/01/1997 - "Autoantibodies in the sera of patients with Goodpasture's syndrome were detected by ELISA using the purified nephritogenic antigen. "
03/01/1996 - "The results indicate that alpha 4(IV)NC1 is a potent nephritogenic antigen like alpha 3(IV)NC1, which has already been recognized as a primary target antigen in Goodpasture's syndrome."
06/01/1997 - "These results indicate that the nephritogenic antigen contains the Goodpasture antigen, defined as the antigen reactive with sera from patients with Goodpasture's syndrome."
|2.||Antigen-Antibody Complex (Immune Complex)
|4.||Immunoglobulin G (IgG)
|7.||antiglomerular basement membrane antibody
|9.||Complement System Proteins (Complement)
|10.||type IV collagen alpha3 chain (Goodpasture antigen)
|1.||Transplantation (Transplant Recipients)