|1.||Badimon, Lina: 9 articles (08/2015 - 06/2008)|
|2.||Bu, Guojun: 9 articles (01/2014 - 01/2004)|
|3.||Llorente-Cortés, Vicenta: 8 articles (08/2015 - 06/2008)|
|4.||Zlokovic, Berislav V: 7 articles (10/2012 - 08/2004)|
|5.||Deane, Rashid: 6 articles (10/2012 - 08/2004)|
|6.||Strickland, Dudley K: 5 articles (07/2015 - 07/2002)|
|7.||Cal, Roi: 4 articles (08/2015 - 10/2011)|
|8.||Emonard, Hervé: 4 articles (01/2015 - 12/2004)|
|9.||Erickson, Michelle A: 4 articles (12/2014 - 12/2010)|
|10.||Hyman, Bradley T: 4 articles (03/2013 - 07/2002)|
01/01/2010 - "The low-density lipoprotein receptor-related protein-1 (LRP-1) is an endocytic receptor mediating the clearance of various extracellular molecules involved in the dissemination of cancer cells. "
07/01/2013 - "The low-density lipoprotein receptor-related protein 1B (LRP1B) is known as a putative tumor suppressor. "
03/15/2013 - "GRN1005 is a peptide-drug conjugate with the ability to penetrate the blood-brain barrier (BBB) and tumor cells by targeting the low-density lipoprotein receptor-related protein-1. "
02/01/2012 - "Surface expression of toxin receptors tumor endothelial marker 8 and capillary morphogenesis gene 2, as well as coreceptor low density lipoprotein receptor-related protein 6 (LRP6), are markedly reduced, preventing toxin binding to platelets. "
11/01/2011 - "There was no correlation between low-density lipoprotein receptor-related protein 1 expression and survival, but a trend was found between low-density lipoprotein receptor-related protein 1 overexpression and tumor recurrence. "
|2.||Alzheimer Disease (Alzheimer's Disease)
05/29/2007 - "Genome-wide linkage studies have defined a broad susceptibility region for late-onset Alzheimer's disease on chromosome 12, which contains the Low-Density Lipoprotein Receptor-Related Protein 6 (LRP6) gene, a coreceptor for Wnt signaling. "
07/15/2005 - "Association study and meta-analysis of low-density lipoprotein receptor related protein in Alzheimer's disease."
03/13/1998 - "Genetic association studies between Alzheimer's disease and two polymorphisms in the low density lipoprotein receptor-related protein gene."
05/01/2014 - "Apolipoprotein E receptor pathways in Alzheimer disease."
06/01/2013 - "We previously found that single nucleotide polymorphisms in the low-density lipoprotein receptor-related protein 6 (LRP6) gene are associated with Alzheimer's disease (AD). "
02/01/1987 - "These results support the interpretation that delayed chylomicron remnant clearance in subjects with endogenous hypertriglyceridemia may be largely secondary to overproduction of VLDL particles, whose remnants compete with chylomicron remnants for removal by the liver via apoE receptor-mediated endocytosis. "
02/01/2013 - "Chronic kidney disease (CKD) results in hypertriglyceridemia which is largely due to impaired clearance of triglyceride-rich lipoproteins occasioned by downregulation of lipoprotein lipase and very low-density lipoprotein (LDL) receptor in the skeletal muscle and adipose tissue and of hepatic lipase and LDL receptor-related protein in the liver. "
07/01/2004 - "The metabolic flow of lipoproteins in normo- and hypertriglyceridemia can be described by separate compartments that contribute to lipoprotein interaction with at least six different receptors: 1) low density lipoprotein (LDL) receptor; 2) LDL receptor-related protein (LRP); 3) apoB(48) macrophage receptor for hypertriglyceridemic very low density lipoproteins (VLDL); 4) scavenger receptors; 5) VLDL receptor; 6) lipolysis-stimulated receptor. "
11/01/2009 - "Hypertriglyceridemia, abnormal composition, and impaired clearance of triglyceride-rich lipoproteins and their remnants are mediated by down-regulation of lipoprotein lipase, hepatic lipase, very low-density lipoprotein (VLDL) receptor, and LDL receptor-related protein, relative reduction in ApoC-II/ApoC-III ratio, up-regulation of acyl-CoA cholesterol acyltransferase, and elevated plasma level of cholesterol ester-poor prebeta HDL. "
|4.||von Willebrand Diseases (von Willebrand's Disease)
03/01/2000 - "We used a murine model of severe von Willebrand disease (vWF knockout mice) to study the effect of a recombinant vWF/pro-vWF preparation (rpvWF) on factor VIII survival and to investigate whether low-density lipoprotein receptor-related protein (LRP) might be involved in the in vivo clearance of factor VIII in the absence of vWF. "
12/01/2015 - "LDL receptor-related protein with 11 ligand binding repeat (LR11) and its soluble form (sLR11) play a role in the progression of atherosclerosis. "
02/01/2011 - "We previously identified a mutation in LDL receptor-related protein 6 (LRP6), LRP6(R611C), that causes early atherosclerosis. "
02/01/2011 - "Carotid artery atherosclerosis in hypertensive patients with a functional LDL receptor-related protein 6 gene variant."
03/16/2007 - "Deletion of macrophage LDL receptor-related protein increases atherogenesis in the mouse."
07/01/1998 - "Low-density lipoprotein receptor-related protein in atherosclerosis development: up-regulation of gene expression in patients with coronary obstruction."
|1.||Peptide Hydrolases (Proteases)
|3.||alpha-Macroglobulins (alpha 2 Macroglobulin)
|4.||Amyloid (Amyloid Fibrils)
|5.||Lipoprotein Lipase (Diacylglycerol Lipase)
|6.||Lipase (Acid Lipase)
|7.||LDL Receptors (LDL Receptor)
|8.||Apolipoproteins E (ApoE)
|10.||Factor VIII (Coagulation Factor VIII)
|3.||Photochemotherapy (Photodynamic Therapy)
|5.||Drug Therapy (Chemotherapy)