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Tumor Suppressor Protein p14ARF (p14ARF)

A gene product of the p16 tumor suppressor gene (GENES, P16). It antagonizes the function of MDM2 PROTEIN (which regulates P53 TUMOR SUPPRESSOR PROTEIN by targeting it for degradation). p14ARF is produced from the beta mRNA transcript of the p16 gene. The other gene product, produced from the alternatively spliced alpha transcript, is CYCLIN-DEPENDENT KINASE INHIBITOR P16. Both p16 gene products have tumor suppressor functions.
Also Known As:
p14ARF; Cdkn2a(p14ARF); p(ARF) Protein; p14(ARF); p14ARF Protein
Networked: 876 relevant articles (11 outcomes, 120 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Rizos, Helen: 10 articles (10/2020 - 02/2003)
2. Gjerset, Ruth A: 10 articles (01/2017 - 10/2002)
3. Rey, Juan A: 10 articles (01/2012 - 03/2003)
4. Kefford, Richard F: 9 articles (02/2010 - 02/2003)
5. Bello, M Josefa: 9 articles (02/2006 - 03/2003)
6. Alonso, M Eva: 7 articles (11/2004 - 03/2003)
7. Gonzalez-Gomez, Pilar: 7 articles (11/2004 - 03/2003)
8. Tannapfel, Andrea: 7 articles (08/2004 - 02/2002)
9. La Mantia, Girolama: 6 articles (01/2019 - 03/2002)
10. Li, Guojun: 6 articles (01/2015 - 03/2011)

Related Diseases

1. Neoplasms (Cancer)
2. Squamous Cell Carcinoma of Head and Neck
3. Carcinogenesis
4. Mesothelioma
5. Inflammation (Inflammations)

Related Drugs and Biologics

1. Complementary DNA (cDNA)
2. Peptides (Polypeptides)
3. Nitric Acid
4. Aerosols
5. Cyclin-Dependent Kinase Inhibitor p16
6. Proteins (Proteins, Gene)
7. Messenger RNA (mRNA)
8. DNA (Deoxyribonucleic Acid)
9. Ubiquitin
10. Tumor Suppressor Proteins (Proteins, Tumor Suppressor)

Related Therapies and Procedures

1. Therapeutics
2. Ligation
3. Drug Therapy (Chemotherapy)
4. Chemoradiotherapy
5. Mediterranean Diet