NAD-Dependent Hydroxymethylglutaryl-CoA Reductases

Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. This class of enzymes performs a catabolic role in microorganisms such as Pseudomonas mevalonii where it oxidatively acetylates MEVALONIC ACID to form 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A and NADH.

Also Known As:

Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent; 3-Hydroxy-3-methylglutaryl CoA-Reductase, NAD-Dependent; HMG CoA Reductase, NAD-Dependent; Hydroxymethylglutaryl CoA Reductase, NAD-Dependent; CoA-Reductase, NAD-Dependent 3-Hydroxy-3-methylglutaryl; HMG CoA Reductase, NAD Dependent; HMG CoA Reductases, NAD Dependent; Hydroxymethylglutaryl CoA Reductase, NAD Dependent; NAD-Dependent 3-Hydroxy-3-methylglutaryl CoA-Reductase; HMG CoA Reductases, NAD-Dependent

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Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Oxidoreductases: 13671
    - Alcohol Oxidoreductases: 56
      - NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases
        3-Hydroxyacyl CoA Dehydrogenases
        Hydroxymethylglutaryl CoA Reductases: 856
        NAD-Dependent Hydroxymethylglutaryl-CoA Reductases