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Neurofibromin 1 (Neurofibromin)

A protein found most abundantly in the nervous system. Defects or deficiencies in this protein are associated with NEUROFIBROMATOSIS 1, Watson syndrome, and LEOPARD syndrome. Mutations in the gene (GENE, NEUROFIBROMATOSIS 1) affect two known functions: regulation of ras-GTPase and tumor suppression.
Also Known As:
Neurofibromin; NF-1 Protein; NF1 GRP; NF1 Protein; NF1-GAP-Related Protein; Neurofibromatosis Type 1 Gene Product; NF 1 Protein; NF1 GAP Related Protein; Neurofibromatosis Type 1 Protein
Networked: 560 relevant articles (3 outcomes, 37 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Gutmann, David H: 26 articles (01/2018 - 07/2002)
2. Parada, Luis F: 10 articles (07/2015 - 07/2002)
3. Ratner, Nancy: 9 articles (01/2020 - 01/2004)
4. Messiaen, Ludwine: 8 articles (06/2022 - 02/2006)
5. Ingram, David A: 8 articles (01/2018 - 06/2006)
6. Scheffzek, Klaus: 7 articles (01/2022 - 12/2004)
7. Khanna, Rajesh: 7 articles (01/2020 - 06/2010)
8. McCormick, Frank: 7 articles (01/2020 - 05/2010)
9. Zhu, Yuan: 7 articles (01/2018 - 07/2002)
10. Kesterson, Robert A: 6 articles (06/2022 - 01/2018)

Related Diseases

1. Neurofibromatosis 1 (Neurofibromatosis Type I)
2. Cardiovascular Diseases (Cardiovascular Disease)
3. Neointima
4. Neoplasms (Cancer)
5. Neurofibrosarcoma (MPNST)

Related Drugs and Biologics

1. Neurofibromin 1 (Neurofibromin)
2. Proteins (Proteins, Gene)
3. GTPase-Activating Proteins (GTPase-Activating Protein)
4. Tumor Suppressor Proteins (Proteins, Tumor Suppressor)
5. Neurofibromin 2 (Merlin)
6. Messenger RNA (mRNA)
7. TOR Serine-Threonine Kinases
8. Peptides (Polypeptides)
9. Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)
10. Intercellular Signaling Peptides and Proteins (Growth Factors)

Related Therapies and Procedures

1. Therapeutics
2. Radiotherapy
3. Drug Therapy (Chemotherapy)
4. Spinal Fusion (Spondylosyndesis)
5. Lasers (Laser)