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Mitochondrial Aspartate Aminotransferase

An aspartate aminotransferase found in MITOCHONDRIA.
Also Known As:
Aspartate Aminotransferase, Mitochondrial; Aminotransferase, Mitochondrial Aspartate; Glutamate Oxaloacetate Transaminase 2; Oxaloacetate Transaminase-2, Glutamate; Transaminase-2, Glutamate Oxaloacetate; Glutamate Oxaloacetate Transaminase-2
Networked: 35 relevant articles (2 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. De Girolamo, Luigi A: 1 article (04/2011)
2. Hargreaves, Alan J: 1 article (04/2011)
3. Burté, Florence: 1 article (04/2011)
4. Billett, E Ellen: 1 article (04/2011)
5. Ishiguro, Sei-Ichi: 1 article (10/2002)
6. Tomita, Hiroshi: 1 article (10/2002)
7. Tamai, Makoto: 1 article (10/2002)
8. Endo, Satoko: 1 article (10/2002)
9. Suzuki, Ken: 1 article (09/2002)
10. Sawa, Yoshiki: 1 article (09/2002)

Related Diseases

1. Liver Diseases (Liver Disease)
01/01/1990 - "[Value of serum mitochondrial aspartate aminotransferase activity as a diagnostic marker of liver disease in heart failure]."
07/01/1986 - "Among the 61 nonalcoholic patients with liver disease, 11 had an increased mitochondrial aspartate aminotransferase/total aspartate aminotransferase ratio, specificity of which was 82%. "
02/01/1985 - "In patients with chronic liver diseases we found a greater increase in the activity of glutamate dehydrogenase than of mitochondrial aspartate aminotransferase and the correlation between the two mitochondrial enzymes was stronger. "
02/01/1985 - "Mitochondrial enzymes in human serum: comparative determinations of glutamate dehydrogenase and mitochondrial aspartate aminotransferase in healthy persons and patients with chronic liver diseases."
10/01/1990 - "These include: the requirement for improved enzymological screening, despite the introduction of a test for hepatitis C; the imbalance between the popularity of "unexplained chronic aminotransferase elevations" and efforts to solve the inherent problems; the inadequate attempts to use the metabolic changes in the hepatocytes to improve diagnosis, prognosis, and pathophysiological understanding of viral liver diseases; the remarkable investigations into the 2'-5'-oligoadenylate synthetase for better control of interferon therapy in chronic viral hepatitis; the use of enzymes as markers of etiology, particularly for the detection of alcohol induced liver diseases; the continuing preference for the aminotransferases in this scenario although the ratios of aspartate aminotransferase over alanine aminotransferase, or of mitochondrial aspartate aminotransferase over total aspartate aminotransferase activity, largely depend on the severity and intralobular localization of damage and the stage of the liver disease."
2. Reperfusion Injury
3. Hepatitis C
4. Hepatitis
5. Alcoholism (Alcohol Abuse)

Related Drugs and Biologics

1. Aspartate Aminotransferases (Aspartate Transaminase)
2. Enzymes
3. Creatine Kinase (Creatine Phosphokinase)
4. Alanine Transaminase (SGPT)
5. Ligases
6. Interferons
7. Transaminases
8. Isoenzymes
9. Glutamate Dehydrogenase
10. Adenosine Triphosphate (ATP)

Related Therapies and Procedures

1. Induced Heart Arrest (Cardioplegia)
2. Decompression