|1.||Bustin, Michael: 8 articles (11/2014 - 04/2003)|
|2.||Furusawa, Takashi: 5 articles (01/2014 - 04/2003)|
|3.||Postnikov, Yuri V: 4 articles (01/2014 - 04/2003)|
|4.||Birger, Yehudit: 4 articles (03/2008 - 04/2003)|
|5.||Wei, Feng: 2 articles (12/2015 - 11/2014)|
|6.||Howard, O M Zack: 2 articles (01/2015 - 11/2014)|
|7.||Oppenheim, Joost J: 2 articles (01/2015 - 11/2014)|
|8.||Li, Sandra: 2 articles (01/2015 - 11/2014)|
|9.||Haines, Diana C: 2 articles (01/2014 - 08/2005)|
|10.||West, Katherine L: 2 articles (08/2005 - 04/2003)|
01/01/2014 - "Our study indicates that in mice, loss of HMGN1 leads to transcription changes that accelerate the progression of DEN-induced hepatocarcinogenesis, without affecting the type of tumors or the final total tumor burden of these mice. "
12/01/2015 - "Additionally, a positive correlation between serum HMGN1 and tumor stage was found in local disease, while serum HMGN1 level in metastatic NSCLC patients was significantly decreased. "
11/01/2014 - "In addition, EG7 tumors expressing HMGN1 grew more slowly than control EG7 tumors, suggesting greater resistance to HMGN1-expressing tumors. "
11/01/2014 - "Tumor-bearing Hmgn1(-/-) mice generated fewer OVA-specific CD8 cells in the spleen than EG7-bearing Hmgn1(+/+) mice, suggesting that HMGN1 supported T cell-mediated antitumor immunity. "
08/01/2005 - "We suggest that HMGN1 optimizes the cellular response to ionizing radiation and to other tumorigenic events; therefore, loss of this protein increases the tumor burden in mice."
08/01/2013 - "HMGN1 modulates nucleosome occupancy and DNase I hypersensitivity at the CpG island promoters of embryonic stem cells."
08/01/2005 - "The ionizing radiation hypersensitivity and the aberrant G2-M checkpoint activation of Hmgn1-/- fibroblasts can be reverted by transfections with plasmids expressing wild-type HMGN1, but not with plasmids expressing mutant HMGN proteins that do not bind to chromatin. "
08/01/2013 - "Here we show that HMGN1, a nucleosome-binding protein ubiquitously expressed in vertebrate cells, preferentially binds to CpG island-containing promoters and affects the organization of nucleosomes, DNase I hypersensitivity, and the transcriptional profile of mouse embryonic stem cells and neural progenitors. "
04/01/2003 - "The UV hypersensitivity of Hmgn1(-/-) MEFs could be rescued by transfection with plasmids expressing wild-type HMGN1 protein, but not with plasmids expressing HMGN1 mutants that do not bind to nucleosomes or do not unfold chromatin. "
03/28/2008 - "We find that loss of HMGN1 decreases the levels of Hsp70 transcripts at the early stages of heat shock. "
01/01/2009 - "Results show that the interactions of NFIX with CGGBP1 and HMGN1 in the soluble fraction are heat shock sensitive due to preferential localization of CGGBP1 to heterochromatin after heat shock. "
01/01/2009 - "Under chronic heat shock, NFIX uses CGGBP1 and HMGN1 to get recruited to this promoter and in turn affects their binding to DNA. "
03/28/2008 - "We suggest that HMGN1 enhances the rate of heat shock-induced H3K14 acetylation in the Hsp70 promoter, thereby enhancing the rate of chromatin remodeling and the subsequent transcription during the early rounds of Hsp70 activation when the gene is still associated with histones in a nucleosomal conformation."
03/28/2008 - "Here we use embryonic fibroblasts from Hmgn1(+/+) and Hmgn1(-/-) mice to examine the effect of HMGN1 on the heat shock-induced transcriptional activation of Hsp70, a well characterized gene known to undergo a rapid chromatin re-structuring during transcriptional activation. "
|4.||Down Syndrome (Down's Syndrome)
10/01/2014 - "CBR1, DYRK1A, HMGN1, ITSN1, RCAN1, SON, TMEM50B, and TTC3 were each up-regulated two-fold in Down syndrome samples compared to normal samples; of these, SON and TTC3 were newly reported. "
12/09/2011 - "High mobility group N1 protein (HMGN1), a nucleosomal-binding protein that affects the structure and function of chromatin, is encoded by a gene located on chromosome 21 and is overexpressed in Down syndrome, one of the most prevalent genomic disorders. "
|5.||Amnesia (Dissociative Amnesia)
10/01/2003 - "Status of the "protein kinase CK2-HMG14" system in age-related amnesia in rats."
05/01/2002 - "[State of the "protein kinase CK2-HMG14" system in age-dependent amnesia in rats]."
10/01/2003 - "Selective activators of protein kinase CK2 (1-ethyl-4-carbamoyl-5-methylcarbamoylimidazole and 1-ethyl-4,5-dicarbamoylimidazole) increased HMG14 phosphorylation by protein kinase CK2, increased transcription, increased the synthesis of synaptosomal proteins, and decreased amnesia for the CPAR in aged rats. "
|3.||Carrier Proteins (Binding Protein)
|4.||HMGN1 Protein (HMGN1)
|5.||Proteins (Proteins, Gene)
|6.||DNA (Deoxyribonucleic Acid)
|7.||Casein Kinase II (Casein Kinase 2)
|8.||HMGN2 Protein (HMGN2)
|9.||Deoxyribonuclease I (Nickase)
|10.||Histone Deacetylase Inhibitors
|1.||Pneumonectomy (Lung Volume Reduction)