|1.||Fusco, Alfredo: 17 articles (01/2015 - 01/2003)|
|2.||Manfioletti, Guidalberto: 9 articles (07/2011 - 07/2002)|
|3.||Esposito, Francesco: 6 articles (01/2015 - 03/2010)|
|4.||Fedele, Monica: 6 articles (04/2012 - 12/2007)|
|5.||Sgarra, Riccardo: 6 articles (07/2011 - 12/2003)|
|6.||Giancotti, Vincenzo: 6 articles (07/2011 - 12/2003)|
|7.||Rustighi, Alessandra: 5 articles (01/2007 - 12/2003)|
|8.||Tessari, Michela A: 5 articles (01/2007 - 12/2003)|
|9.||D'Angelo, Daniela: 4 articles (01/2015 - 03/2013)|
|10.||Palmieri, Dario: 4 articles (03/2013 - 03/2009)|
12/01/2004 - "Our studies indicate that HMGA molecules might be biologically and pathologically relevant factors in neuroblastic tumor development and progression."
06/01/2003 - "In conjunction with studies involving rearrangements of HMGA genes in other benign mesenchymal tumors, our results support a model in which the expression of the wild-type HMGA allele is critical for the pathogenesis of mesenchymal tumors and in which rearrangements of HMGA do not lead to a gain of function in the chimeric HMGA protein."
09/30/2014 - "HMGA overexpression is a feature of human cancer and plays a causal role in cell transformation. "
03/01/2014 - "Since changes in expression of HMGA are considered as a marker of tumor progression, it is possible that similar changes in expression of NUCKS could be a useful tool in diagnosis of malignant skin tumors. "
01/01/2014 - "In this review, we will focus on recent advances in understanding the function of HMGA family members, specifically their role in gene transcription regulation during development and cancer. "
|3.||Pituitary Neoplasms (Pituitary Adenoma)
01/01/2015 - "Numerous studies have established that High Mobility Group A (HMGA) proteins play a pivotal role on the onset of human pituitary tumors. "
10/01/2015 - "Transgenic mice overexpressing the high mobility group A (HMGA) genes, Hmga1 or Hmga2 develop pituitary tumours and their overexpression is also a frequent finding in human pituitary adenomas. "
01/01/2015 - "Epigenetic Mechanisms Leading to Overexpression of HMGA Proteins in Human Pituitary Adenomas."
04/01/2012 - "Finally, the expression analysis of HMGA1, HMGA2 and PIT1 in human pituitary adenomas of different histological types revealed a direct correlation between PIT1 and HMGA expression levels. "
09/15/2010 - "Here, we overview HMGA proteins in human tumours, focusing on pituitary adenomas and the mechanisms by which the HMGA proteins are involved in their onset and development. "
05/01/2012 - "The objective of this study was to analyze the expression and clinical role of the high mobility group AT hook (HMGA) protein in advanced-stage serous ovarian carcinoma. "
01/01/2015 - "Even though HMGA proteins' overexpression indicates a poor prognosis in almost all malignancies, their detection may be particularly useful in determining the prognosis of breast, lung, and colon carcinomas, suggesting for the treatment a more aggressive therapy. "
06/01/2006 - "As HMGA proteins were expressed in about 90% of lung carcinomas and their expression was inversely associated with survival, they may provide useful markers for lung cancer diagnosis and prognosis."
06/01/2006 - "In this work, the expression of HMGA 1 and 2 in 152 lung carcinomas of mainly non-small-cell histological type has been studied by immunohistochemistry in order to evaluate their feasibility as lung cancer markers. "
|5.||Hepatocellular Carcinoma (Hepatoma)
01/01/2003 - "Thus, hepatocellular carcinoma represents the first case of malignant neoplasia in which HMGA1 expression is not induced, which presents a striking contrast to several previous studies demonstrating the significance of increased HMGA gene/protein levels in carcinogenesis and/or tumor progression. "
|2.||Proteins (Proteins, Gene)
|4.||DNA (Deoxyribonucleic Acid)
|7.||ataxia telangiectasia mutated protein
|1.||Drug Therapy (Chemotherapy)