|1.||Strle, Franc: 3 articles (11/2015 - 07/2002)|
|2.||Petrovec, Miroslav: 3 articles (11/2015 - 07/2002)|
|3.||Frohlich, Mark W: 3 articles (09/2011 - 07/2010)|
|4.||Engert, A: 3 articles (04/2003 - 09/2000)|
|5.||Goldberg, Alisa B: 2 articles (09/2015 - 12/2008)|
|6.||Winikoff, Beverly: 2 articles (09/2015 - 12/2008)|
|7.||Ko, Wen-Chien: 2 articles (06/2014 - 06/2012)|
|8.||Chen, Po-Lin: 2 articles (06/2014 - 06/2012)|
|9.||Lai, Chung-Hsu: 2 articles (01/2014 - 01/2008)|
|10.||Mori, Takehiko: 2 articles (01/2014 - 04/2006)|
|1.||Anti-Bacterial Agents (Antibiotics)IBA
01/01/2015 - "Twenty-four infectious episodes (6%) occurred in 18 subjects, and 5 CVCs required removal; all patients requiring removal admitted and received antibiotics owing to chills. "
01/01/2013 - "Among patients aged 18 to 79 years, shaking chills (adjusted odds ratio [AOR] 2.22, 95% confidence interval [CI]: 1.09-4.51) and previous antibiotics use (AOR 0.08, 95% CI: 0.01-0.68) were significant. "
06/01/1998 - "As for independent background factors related to prescription of antibiotics for acute bronchitis, the odds ratio was higher in physicians denying the efficacy of antibiotics for treating a cold (4.58, 1.94-10.8), and the patients with complaints such as purulent sputum (22.9, 2.66-197.2), more severe findings of the pharynx (2.26, 1.34-3.79) and of the chest (2.73, 1.53-4.88), and those who had a body temperature measurement taken (4.42, 1.71-11.4) and a chest X-ray (6.11, 1.07-34.9), but was lower in those complaining of chills (0.16, 0.04-0.66) and diarrhoea (0.11, 0.01-1.11). "
01/01/2013 - "Exposures were a history of shaking chills, prior antibiotics use within 48 hours, vital signs, and laboratory inflammation markers on admission. "
07/01/2009 - "A 35-year-old woman with a 10-year history of SLE had intermittent fever with chills that was refractory to empirical antibiotics. "
|2.||Amphotericin B (Amphotericin)FDA LinkGeneric
02/01/1997 - "Intravenous therapy with the standard drug conventional amphotericin-B is associated with severe adverse effects like nephrotoxicity and chills. "
12/01/1989 - "Premedication for amphotericin B-induced chills."
09/26/2003 - "Amphotericin B administration is limited by infusion-related toxicity, including fever and chills, an effect postulated to result from proinflammatory cytokine production by innate immune cells. "
08/01/1998 - "Infusion-related hypoxia and chills were more common in ABCD recipients than in amphotericin B recipients (P = .013 and P = .018, respectively). "
08/01/1996 - "Toxic effects of amphotericin B included nephrotoxicity, hypokaliemia, and fever and chills. "
|3.||rituximab (Mabthera)FDA Link
12/01/2011 - "Patient records were reviewed to determine demographic data, CRS, vital signs, evidence of chills/rigors, use of rescue medications, and rituximab infusion rates. "
05/01/2011 - "Rechallenge with rituximab 25 mg/h was attempted, but the blood pressure again declined and the patient experienced chills and rigors. "
09/15/2007 - "One patient experienced grade II infusion-related chills associated with rituximab. "
01/15/2001 - "Twenty-nine of 31 responding patients remained in remission during this follow-up period, including 15 of 16 patients with an IPI score > or = 2. The most frequent adverse events attributed to Rituxan were fever and chills, primarily during the first infusion. "
10/01/2011 - "Only infusion reactions, such as rash and chills, occurred after single-dose rituximab infusion and can be managed by pre-medication or infusion rate adjustments. "
01/01/2010 - "The published Phase-1 cancer studies have shown that lipid A analogues are usually well tolerated, most of the side effects being likely related to immune response, i. e., fever, chills and rigor. "
03/01/2009 - "Amphotericin B lipid complex (ABLC), a lipid-based formulation of amphotericin B, is an effective treatment for fungal infections, but is associated with mild to moderate drug delivery reactions (DDRs), such as fever, rigors and chills, in some patients. "
|5.||Misoprostol (Cytotec)FDA LinkGeneric
02/01/2011 - "Shivering and chills were significantly more common with misoprostol. "
03/01/2011 - "A dose-related rise in the body temperature and chills was observed in the misoprostol groups, with 8.3%, 8.3% and 45% of women experiencing a fever >39 °C with the 200, 400, and 600 mcg doses respectively. "
12/01/2008 - "Adverse effect profiles were similar, although fever and chills were reported approximately 10% more often among women who took buccal misoprostol. "
10/07/2006 - "Women taking misoprostol had a higher rate of transitory symptoms of chills and fever than the control. "
09/01/2015 - "Patients given misoprostol had significantly more pain, fever, and chills. "
|6.||Acetaminophen (Paracetamol)FDA LinkGeneric
03/01/2001 - "Side effects were minimal and well tolerated, and consisted of chills and a slight fever, which resolved with the administration of acetaminophen. "
07/01/1999 - "Subjective symptom scores for chills and perception of fever were higher in the placebo group than in the acetaminophen group (chills, 2.5 +/- 0.3 versus 1.0 +/- 0.2, P = .009 and fever, 2.5 +/- 0.2 versus 2.0 +/- 0.2, P = .021). "
05/01/1998 - "Mild fever and chills were observed in 75% of the patients but rarely required acetaminophen. "
02/01/1993 - "Occasional headaches, myalgias, or chills occurred in 30% to 60% of rIFN-gamma-treated patients but were effectively prevented by pretreatment acetaminophen and by dosing at bedtime. "
08/01/1990 - "Fever, chills and headache were worse with the first two doses and were usually relieved with acetaminophen. "
09/01/2011 - "Constitutional IL-2 toxicities included indurate injection site (57.5%), fever (60%), chills (55%), itchy skin (42.5%), bone pain (32.5%) and myalgia (45%). "
10/01/2010 - "At lower doses the treatment was well tolerated; the most frequent adverse events were mild fever, chills and abdominal pain, without exacerbation in the IL-2 combined cycles. "
12/01/2002 - "IL-2-related toxicities such as fever, chills, and fatigue were less common with the reduced doses of IL-2. "
03/01/1999 - "Toxicity related to IL-2 included fever, chills, malaise, and eosinophilia. "
05/01/1988 - "Side effects of interleukin 2 therapy included fever, chills, anorexia and fatigue. "
06/01/2011 - "Initial presentation with temperature>38.7°C (0.4, 0.2-0.6), chills (0.6, 0.4-0.99) and highest quartile of the inflammatory marker C-reactive-protein (0.3, 0.2-0.5) were independent protective factors. "
11/01/2005 - "In the second scenario, the important variables were chills, C-reactive protein, and physician diagnosis of a low-risk site. "
09/01/2003 - "Clinical symptoms of the patients with Mycoplasma-positive results were compared to those of the other patients with lower-respiratory-tract infections, and it was found that the results for mean lower age numbers as well as the presence of chills, increased erythrocyte sedimentation rate, and raised C-reactive protein levels showed significant differences. "
04/01/2013 - "A female patient presented with recurrent attacks of chills, fever and abdominal pain was found to have simultaneous cyclic oscillation in leukocyte counts and C-reactive protein values. "
12/01/1990 - "Two days later, he suddenly had chills and a fever, and the laboratory data showed leukocytosis and a positive C-reactive protein (CRP). "
|9.||Muromonab-CD3 (Muromonab CD3)FDA Link
01/27/1996 - "Patients treated with TNFR:Fc had significantly fewer symptoms by day 2 of OKT3, and had a lower overall incidence of chills and arthralgias. "
06/01/1986 - "The first OKT3 injection resulted in a dramatic decrease in T3+, T4+, and T8+ cells, while patients simultaneously experienced fever, chills, and diarrhea. "
12/01/1984 - "Fever, chills, and, in some instances, dyspnea following the first dose of OKT3 were the only side-effects observed. "
05/01/1994 - "Side effects of OKT3 treatment were fever, chills, intestinal complications, hemodynamic response, convulsions, and viral infections.(ABSTRACT TRUNCATED AT 250 WORDS)"
05/01/1991 - "All patients tolerated OKT3, although most had symptoms--pyrexia, chills, dyspnea, nausea and vomiting, and fever--within an hour after the dose. "
|10.||liposomal amphotericin BFDA Link
01/01/2010 - "Children receiving a colloidal dispersion were more likely to develop such reactions than with liposomal amphotericin B (chills: RR 1.76, 95% CI 1.09 to 2.85, P = 0.02). "
01/01/2002 - "Furthermore in a recent multicenter double-blind study it has been shown that Ambisome has a better safety profile than Abelcet with less chills/rigors and less nephrotocixity."
01/01/2010 - "Children receiving liposomal amphotericin B were less likely to develop infusion-related reactions compared with conventional amphotericin B (chills: RR 0.37, 95% CI 0.21 to 0.64, P = 0.0005). "
02/01/2002 - "Patients in both AmBisome treatment groups experienced less chills/rigors, less nephrotoxicity based on a doubling of serum creatinine, and fewer toxic reactions resulting in discontinuation of therapy. "
05/01/2002 - "Out of the 695 infusions of c-amp B fever occurred on 25.04% occasions in 68.42% patients, while it occurred on 2.09% occasions out of 767 infusions (in 30.43% patients of L-AMP-LRC-1. Chills occurred on 16.83% and 1.17% occasions after c-amp B and liposomal amphotericin B respectively. "
|1.||Drug Therapy (Chemotherapy)
01/01/2015 - "She developed chills, rigor, and diarrhea, necessitating admission on the 7th day of the third course of chemotherapy. "
04/01/2004 - "Febrile shivering is common during chills of fever, blood product transfusions, administration of antigenic drugs, and chemotherapy. "
11/15/2000 - "Adverse effects include infusion-related reactions manifested by fever and chills, exacerbation of chemotherapy-induced gastrointestinal toxicity and myelosuppression, and cardiotoxicity. "
06/01/2015 - "We report a case of a lung cancer patient who did not receive chemotherapy, presenting to the emergency department with fever and chills. "
07/01/2005 - "He developed fever (38.5-39 degrees C), chills, cough and morning expectoration after the 61 courses of chemotherapy. "
12/01/2004 - "At presentation with FN, the proportions of patients (1) with PBC-ALL versus other malignancies, (2) with other malignancies being in complete remission, (3) with a central venous catheter, and (4) with shaking chills all significantly increased over time (overall proportions, 64%, 60%, 50%, and 5%, respectively; p <0.001 for all). "
05/01/2007 - "Five variables were independently associated with bacteremia: residence at home rather than in an institution (OR 4; 95%CI 1.5-10.7), presence of an indwelling urinary catheter (OR 3.3; 95%CI 1.3-8.8), presence of band forms in the blood count (OR 3.3; 95%CI 1.5-7.2), shaking chills (OR 2.3; 95%CI 1.1-4.8), and neutrophilia (OR 1.1; 95%CI 1.04-1.15). "
03/01/2002 - "Blood cultures were positive in 98 of 129 of episodes (76%) in which patients dialyzing with a catheter had fever or chills. "
08/01/2000 - "She was dialyzed via a tunneled left subclavian catheter, but after 1 year developed chills and fever during each dialysis session. "
07/01/1984 - "Ten had fever and/or chills, and in six of these patients microorganisms were cultured from arterial blood or central venous catheter tips. "
|3.||Homologous Transplantation (Allograft)
|5.||Fluid Therapy (Oral Rehydration Therapy)