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Antimicrobial Cationic Peptides

Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.
Also Known As:
Amphipathic Cationic Antimicrobial Peptides; Antimicrobial Peptides, Cationic; Cationic Peptides, Antimicrobial; Cationic Proteins, Microbicidal; Peptides, Antimicrobial Cationic; Peptides, Cationic Antimicrobial; Proteins, Microbicidal Cationic; Cationic Antimicrobial Peptides; Microbicidal Cationic Proteins
Networked: 75 relevant articles (1 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Hoskin, David W: 4 articles (10/2013 - 08/2006)
2. Nizet, Victor: 3 articles (11/2015 - 11/2006)
3. Shafer, William M: 2 articles (07/2014 - 08/2005)
4. Hilchie, Ashley L: 2 articles (10/2013 - 01/2011)
5. Doucette, Carolyn D: 2 articles (10/2013 - 01/2011)
6. Trent, M Stephen: 2 articles (01/2013 - 12/2004)
7. Zhanel, George G: 2 articles (02/2012 - 10/2010)
8. Findlay, Brandon: 2 articles (02/2012 - 10/2010)
9. Schweizer, Frank: 2 articles (02/2012 - 10/2010)
10. Liu, Lihong: 2 articles (01/2011 - 04/2010)

Related Diseases

1. Meningitis
2. Infection
3. Neoplasms (Cancer)
4. Multiple Myeloma
5. Breast Neoplasms (Breast Cancer)

Related Drugs and Biologics

1. pleurocidin
2. Defensins
3. Anti-Bacterial Agents (Antibiotics)
4. Peptides
5. Lipid A
6. CAP18 lipopolysaccharide-binding protein (Bac4)
7. beta-Defensins
8. Cathelicidins
9. Collectins (Collectin)
10. Octoxynol (Triton X 100)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Prostheses and Implants (Prosthesis)
3. Therapeutics
4. Photochemotherapy (Photodynamic Therapy)
5. Drug Therapy (Chemotherapy)