beta-Defensins

10/01/2004 - "Additionally, this study showed that adenovirus-mediated HBD6 expression increases neutrophil recruitment, a recently described attribute of beta-defensins, with mild accentuation of PIV3 activity and inflammation."
01/01/2019 - "Characterization of grass carp (Ctenopharyngodon idella) beta-defensin 1: implications for its role in inflammation control."
04/01/2013 - "Human beta-defensin DEFB126 is capable of inhibiting LPS-mediated inflammation."
01/01/2013 - "Proven association increased expression of alpha-and beta-defensins with activity and a length of inflammation in the intestine at UC."
03/01/2012 - "The production of beta-defensins from granulocytes would allow protection of exposed tissues from microbial invasion avoiding a persistent inflammation, a process that leads to tissue regeneration."

01/01/2012 - "In previous studies we showed the ideal antibacterial activity-profile of the human beta-defensin 2 (hBD-2) for orthopaedic infections and therefore hypothesized that hBD-2 may be the effector of antimicrobial platelet action. "
05/15/2006 - "Contribution of alpha- and beta-defensins to lung function decline and infection in smokers: an association study."
07/23/2004 - "In this study we show a significant correlation between a single-nucleotide polymorphism in the 5'-untranslated region of the DEFB1 gene, which probably regulates the gene expression of human beta defensin 1 (hBD-1) and the risk of HIV-1 infection in an Italian paediatric population (97 HIV-1 perinatally infected children), pointing to the importance of innate immunity in HIV-1 infection."
12/01/1999 - "This is a study aimed at the molecular mechanisms of beta-defensins gene expression and it's gene transfer experiments for preventing mucosal infection. "
01/01/2021 - "We demonstrate that these microvesicles display decreased miR-28-5p, -484, -584-3p, and -584-5p, and let-7b-3p, as well as increased beta-defensin 1 after SIV infection. "

12/01/2004 - "The present work was AIMED on the study of human beta-defensin 3 (hBD-3) gene expression in A431 cell line and human vulval tumors. "
01/01/2019 - "Human Beta Defensins and Cancer: Contradictions and Common Ground."
06/01/2009 - "Human papillomavirus-associated induction of human beta-defensins in anal intraepithelial neoplasia."
03/01/2007 - "The above results establish a solid foundation for further studying the biological properties and the anti-tumor mechanism of beta defensins."
12/01/2004 - "Human beta-defensin 3 (hBD-3) expression in A431 cell line and human vulval tumors."

01/01/2020 - "Additionally, we performed an experimental human in vivo study on ten male students where we artificially generated bilateral gluteal wounds and analyzed the influence of the Vivostat PRF® treatment on the expression of two genes (human beta Defensin-2, ((hBD-2) and human beta-Defensin-3 (hBD-3)) in keratinocytes of resected wound specimens that are induced during wound healing. "
01/01/2020 - "Human beta defensins may be a multifactorial modulator in the management of diabetic wound."
01/01/2017 - "Plasma samples and liver samples of 56 male C57BL/6 N-mice with a thorax trauma and a femur fracture were analysed by ELISA, real-time PCR and immunohistochemistry for murine beta defensin 4 (MBD-4) and compared with the expression of control group without trauma. "
03/01/2012 - "Wounding in lizards results in the release of beta-defensins at the wound site and formation of an antimicrobial barrier."
03/01/2007 - "Besides their microbicidal functions, human beta-defensins (hBD) and LL-37 activate different immune and inflammatory cells, and their expression is enhanced in inflamed skin and cutaneous wound sites. "

05/01/2005 - "This study examines the effects on pathogens of the epidermis engineered to express human beta-defensin 3 (HBD3) to combat bacterial infections. "
09/01/2003 - "The data presented in this study provide evidence that airway beta-defensin-2-gene transfer can protect the rat against bacterial infection in vivo, suggesting the beta-defensins as part of the innate host defense system can be of potential applicability."
03/09/2023 - "Our results showed that a GDM-associated hyperglycemic environment induced an inflammatory response and a decreased beta defensins synthesis unable to restrain bacterial infection. "
01/01/2004 - "beta-defensins may contribute to this antibacterial activity and play an important role in renal epithelial resistance to bacterial infections."
12/01/2003 - "Given the antimicrobial function of beta-defensins, they have a putative role in protecting spermatozoa and the epididymis from bacterial infections."