|1.||Wounds and Injuries (Trauma)
|1.||Singer, Adam J: 10 articles (06/2010 - 03/2002)|
|2.||Amadio, Peter C: 9 articles (12/2012 - 06/2002)|
|3.||Zhao, Chunfeng: 9 articles (12/2012 - 06/2002)|
|4.||An, Kai-Nan: 8 articles (12/2012 - 06/2002)|
|5.||Grinstaff, Mark W: 6 articles (05/2011 - 05/2002)|
|6.||Zobitz, Mark E: 6 articles (11/2004 - 06/2002)|
|7.||Grobman, William A: 5 articles (06/2015 - 03/2006)|
|8.||Al-Qattan, Mohammad M: 5 articles (04/2015 - 05/2011)|
|9.||Caughey, Aaron B: 5 articles (10/2013 - 11/2005)|
|10.||Smith, Gary A: 5 articles (03/2012 - 04/2003)|
|1.||Lidocaine (Xylocaine)FDA LinkGeneric
03/01/1999 - "This study assessed the efficacy of buffered lidocaine in children and adults for the repair of simple lacerations. "
02/01/1995 - "The second was given on the opposite side of the laceration after topical application of study solution, which was 5 mL of either 2% lidocaine or saline placebo. "
01/01/1995 - "Lidocaine via iontophoresis in laceration repair: a preliminary safety study."
04/01/2009 - "The literature has shown that the induction of anaesthesia in lacerations has remained largely unchanged over the past few years, with lidocaine infiltration still the preferred method. "
06/01/1999 - "Use of topical lidocaine in pediatric laceration repair."
|2.||Epinephrine (Adrenaline)FDA LinkGeneric
07/01/2000 - "At triage the lacerations were randomized to LET solution or a placebo containing epinephrine 1:1,000. "
08/01/1969 - "The diagnosis of traumatic laceration of the spleen by selective arteriography, direct serial magnification angiography, and intra-arterial epinephrine."
12/01/1992 - "Adrenaline-cocaine gel preparation provides excellent anesthetic efficacy for minor dermal lacerations in children. "
12/01/1992 - "To evaluate the anesthetic efficacy of a gel form of adrenaline-cocaine topical medication for minor dermal laceration repair. "
01/01/2005 - "Lacerations were randomised to local or regional infiltration of lidocaine (lignocaine) 1% with adrenaline (epinephrine) 1:100 000 using a number 27 needle. "
|3.||Tetracaine (Amethocaine)FDA LinkGeneric
11/01/1996 - "Injection 2 was given on the opposite side of the laceration after topical application of a study solution that was 4 mL of either tetracaine or normal saline. "
12/01/1990 - "The tetracaine component of TAC is superfluous for obtaining topical anesthesia of minor dermal lacerations of the face in children. "
11/01/1991 - "The investigators hypothesized that there are no measurable plasma cocaine or tetracaine levels after application of TAC in a swine laceration model. "
05/01/1990 - "The combination of tetracaine, adrenalin, and cocaine (TAC) has become increasingly popular as a topical anesthetic for the suturing of simple skin lacerations. "
10/01/1988 - "A maximal dosage of 3 ml of TAC (containing 175 mg cocaine and 7.5 mg tetracaine) was applied to each laceration. "
|4.||Midazolam (Versed)FDA LinkGeneric
02/01/1995 - "Oral midazolam (0.3 mg/kg) is a safe and effective treatment for reducing anxiety during the suturing of lacerations in children less than 10 years of age. "
09/01/1990 - "We conclude that a single oral dose of midazolam (0.2 mg/kg) is a safe and effective treatment for alleviating anxiety in children less than 6 years old during laceration repair in the ED."
03/01/1993 - "A randomized, double-blind, and controlled study was conducted to evaluate the efficacy of intranasal midazolam for reducing stress during the suturing of lacerations in preschool children. "
12/01/1994 - "To determine the efficacy of rectal midazolam as sedation for laceration repair in preschool children in the pediatric emergency department. "
12/01/1994 - "Efficacy of rectal midazolam for the sedation of preschool children undergoing laceration repair."
|5.||Cocaine (Cocaine HCl)IBA
10/01/1999 - "In our study, application of viscous cocaine-containing TAC solutions to small lacerations did not produce clinically important cocaine absorption."
08/01/1992 - "Cocaine is also absorbed after TAC is applied to dermal lacerations and may cause toxicity by this route. "
07/01/1992 - "We report such a case with extensive laceration of the maternal urinary bladder occurring after ingestion of cocaine."
02/01/1992 - "Only two children had levels of more than 100 ng/mL. No significant correlation between patient or laceration characteristics and cocaine levels was detected. "
01/01/2011 - "To compare the efficacy and safety of infiltrated local anaesthetics with those of topical local anaesthetics for repair of dermal lacerations and to evaluate the efficacy and safety of various single or multi-component topical anaesthetics to identify cocaine-free topically applied local anaesthetics that may provide equivalent analgesia to those containing cocaine. "
|6.||Tissue Adhesives (Tissue Adhesive)IBA
10/15/2008 - "The tissue adhesive hair apposition technique also is effective in repairing scalp lacerations. "
04/01/2008 - "In 6 studies (584 lacerations), tissue adhesives were significantly favored over SWC in time to complete the procedure. "
02/01/2003 - "Tissue adhesives for traumatic lacerations: a systematic review of randomized controlled trials."
09/01/2002 - "A randomised, controlled trial comparing a tissue adhesive (2-octylcyanoacrylate) with adhesive strips (Steristrips) for paediatric laceration repair."
10/01/2000 - "The sample was taken from the client population presenting with lacerations requiring tissue adhesive closure, within the limitations of the study (n = 63). "
08/01/2012 - "The objective of this study was to compare the efficacy of 3 doses of intranasal ketamine (INK) for sedation of children from 1 to 7 years old requiring laceration repair. "
10/01/1998 - "During the study period i.v. ketamine was administered 156 times, primarily for laceration repair and fracture reduction. "
12/01/2012 - "We evaluated the clinical usefulness of N(2)O compared with intravenous ketamine when used for the repair of lacerations in children in the ED. "
12/01/2012 - "Ketamine is used intramuscularly or intravenously as a sedative when repairing the skin lacerations of children in many emergency departments (EDs). "
08/01/2012 - "Intranasal ketamine for procedural sedation in pediatric laceration repair: a preliminary report."
|8.||Anti-Bacterial Agents (Antibiotics)IBA
02/01/1983 - "A prospective study was undertaken to review the efficacy of antibiotics in the treatment of patients with minor lacerations. "
09/01/2012 - "The aim of this study was to assess the need for, and the feasibility to perform, a randomised controlled trial to evaluate the role of prophylactic antibiotics in simple hand lacerations. "
08/01/1986 - "This article is a collective review of all the prospective clinical studies that assessed the therapeutic value of antibiotics in minor soft tissue lacerations. "
06/01/1977 - "A prospective trial of prophylactic antibiotics in hand lacerations."
03/01/2014 - "Women with an operative vaginal delivery (compared with those who delivered spontaneously) and women with third- or fourth-degree laceration were more likely to receive prophylactic antibiotics. "
|9.||Fentanyl (Sublimaze)FDA LinkGeneric
12/01/1994 - "To evaluate the safety and efficacy of two doses of oral transmucosal fentanyl citrate (OTFC) for premedication of children undergoing laceration repair. "
12/01/1994 - "Oral transmucosal fentanyl citrate for premedication of children undergoing laceration repair."
05/01/2002 - "To determine whether a combination of oral transmucosal fentanyl (Fentanyl Oralet, Abbott Laboratories, North Chicago, IL) plus oral midazolam has an acceptable safety profile and is more effective than oral midazolam alone for sedation during laceration repair in a pediatric emergency department (ED). "
05/01/2002 - "A randomized, clinical trial of oral midazolam plus placebo versus oral midazolam plus oral transmucosal fentanyl for sedation during laceration repair."
05/01/2002 - "The addition of oral transmucosal fentanyl to oral midazolam did not improve pain or activity scores in pediatric patients given sedation for laceration repair. "
03/01/1991 - "A systemic reaction to bovine thrombin via large venous lacerations is suspected. "
01/01/2009 - "Inferior epigastric artery pseudoaneurysm with underlying laceration may not respond to percutaneous thrombin injection, whereas coil embolization is shown to be effective."
11/01/2013 - "Percutaneous thrombin injection has been described in case reports as an alternative to surgical intervention for the treatment of hepatic artery pseudoaneurysms associated with high-grade liver lacerations in adults. "
11/01/2013 - "We report successful application of percutaneous thrombin injection in an infant to treat a pseudoaneurysm of a left hepatic arterial branch in an 11-month-old girl with a grade IV liver laceration after superselective transcatheter arterial embolization failed to achieve thrombosis. "
01/01/1990 - "Topically applied chitosan fails to improve the control of bleeding in a liver laceration model when compared to pressure alone in both normal and heparinized rats, and both chitosan and pressure alone are significantly less effective in controlling bleeding than the application of thrombin. "
05/01/2008 - "Episiotomy had no impact on perineal lacerations (OR 0.9) but had very strong protective effects for other lacerations (OR 0.1). "
02/01/2001 - "Our study shows relevant medical advantages for a delivery in water: and a significant reduction of the duration of the first part of labour, significant less episiotomies and perineum lacerations and no need for painkillers. "
02/01/2001 - "The significant reduction on episiotomies (1%) in comparison to the one on the traditional bed (20%) or on the stool (10%) for primiparae in water doesn t mean an increase at perineum lacerations. "
09/01/1999 - "One-to-One practice was associated with a significant reduction in the use of epidural anaesthesia (odds ratio (OR) 95 per cent confidence interval (CI) = 0.59 (0.44, 0.80)), with lower rates of episiotomy and perineal lacerations (OR 95 per cent CI = 0.70 (0.50, 0.98)), and with shorter second stage labour (median 40 min vs 48 min). "
02/01/1997 - "At our institution a statistically and clinically significant reduction in the use of episiotomy for operative vaginal deliveries was not associated with a change in the rate of third-degree lacerations but was associated with an increase in the rate of vaginal lacerations and a decrease in the rate of fourth-degree lacerations."
03/01/2003 - "The obliquely placed modified Kessler or cruciate sutures significantly improved the repair strength in the tendons with an oblique laceration. "
07/01/2012 - "This prospective, controlled, single-blinded, pseudorandomized trial enrolled consecutive ED patients who met the eligibility criteria (age > 19 years, simple lacerations, nonabsorbable sutures, immunocompetent). "
06/01/2011 - "This article describes a quantitative study of whether absorbable sutures are as beneficial as non-absorbable sutures in the management of simple scalp lacerations in adults. "
07/01/2010 - "In a prospective clinical study, 15 patients with clean-cut complete lacerations of the profundus tendon in the distal part of zone I underwent the modified repair technique of three separate 'figure of eight' sutures with the palmar plate included in the suture distally and 7 mm suture purchase proximally, with postoperative immediate active motion that ensured full active extension of the interphalangeal joints. "
04/01/2008 - "Lacerations requiring deep sutures were excluded in 4 studies. "
10/01/1996 - "This TAC application technique was safe and highly effective in providing anesthesia for minor oral lacerations."
12/01/2004 - "LAT gel appears to be a safe and effective means of providing anesthesia for the repair of simple finger lacerations in children. "
03/04/1996 - "Topical anesthesia is a safe and effective means of anaesthetising selected lacerations for suturing. "
05/01/1995 - "Patients with facial or scalp lacerations suitable for topical anesthesia presenting to the ED were included when study physicians were in attendance. "
08/01/2013 - "Examination under anesthesia revealed a 6-cm laceration of the posterior fornix, which extended into the abdominal cavity. "
09/01/1979 - "Twenty-nine adult rhesus monkeys underwent complete laceration of both tibial nerves at mid-thigh level and repair by different methods to study the relative efficacy of autogenous interfascicular nerve grafts. "
10/01/2009 - "Secondary graft repairs for lacerations had good outcomes for the thigh-then-buttock-level tibial (80%/62%), followed by common peroneal divisions at the same levels (45%/24%). "
09/01/2012 - "Studies were included if they involved patients with digital nerve lacerations in whom end-to-end neurorrhaphy, nerve grafts, conduits, or end-to-side neurorrhaphy were performed. "
09/01/2015 - "Two lacerations measured 4 × 1 × 1 cm in the medial margin of the graft and 1 × 1 × 1.5 cm in the front side of the graft, respectively. "
08/01/2015 - "In the arthroscopic observations, results for group P were significantly better than for group R concerning postoperative laceration and fibrous tissue coverage of the grafts (P = .0479). "
05/01/1997 - "This study investigated the issue of informed consent by surveying parent preferences for local anesthesia and sedation in the repair of small lacerations in their children in the emergency department (ED). "
11/01/1996 - "A prospective, randomized, double-blind trial was conducted involving adults with lacerations being repaired following local anesthesia. "
01/01/2015 - "To compare local infiltration anesthesia (LIA) and peripheral nerve block (PNB) in repairing hand lacerations. "
01/01/2015 - "Comparison of local infiltration anesthesia and peripheral nerve block: a randomized prospective study in hand lacerations."
06/01/2008 - "Open reduction through external laceration and bioabsorbable fixation under local anesthesia is a reliable and useful method for the treatment of extensive and comminuted nasal fractures."