Lyme Disease Vaccines

02/01/2011 - "An effective human Lyme disease vaccine that has been adequately evaluated in the highest-risk population groups could be very beneficial in preventing Lyme disease; however, it would need to meet high standards regarding safety, efficacy, cost, and public acceptance."
02/01/2000 - "Lyme disease vaccine efficacy against Lyme disease was 80% for definite and asymptomatic cases and 76% for definite cases at year 2 using the recommended dosage regimen [30 microg at months 0, 1 and 12 (0, 1, 12 schedule)] in a randomised, double-blind, multicentre trial in 10,936 enrolled adult volunteers who resided in areas of the US endemic for Lyme disease. "
01/01/2001 - "The Lyme disease vaccine is safe and effective at preventing transmission of Lyme disease. "
07/01/2000 - "Advances from genetic cloning have improved our understanding of the immune mechanisms associated with treatment-resistant Lyme arthritis and enabled the development of the first Lyme disease vaccine. "
02/01/2000 - "Long term protection against Lyme disease appears to be possible with Lyme disease vaccine. "

02/22/2002 - "Based on reporting to VAERS, we did not detect unexpected or unusual patterns of reported adverse events following Lyme disease vaccine administration, other than hypersensitivity reactions, compared with adverse events observed in clinical trials."
04/01/2000 - "Starting with the newly licensed Lyme disease vaccine, which is not yet approved for children younger than 15 years of age, the article discusses potential vaccines for severe allergy and cocaine abuse and stresses some of the new techniques in needleless vaccination, including the edible plant technology."

03/19/2002 - "10 936 participants enrolled in a phase III trial of Lyme disease vaccine; 118 participants had erythema migrans in which Borrelia burgdorferi was detected by culture or polymerase chain reaction. "

03/01/1994 - "Ability of canine Lyme disease vaccine to protect hamsters against infection with several isolates of Borrelia burgdorferi."
05/01/2009 - "The expansion of Lyme disease's endemic range, as well as the difficulty of diagnosing infection and the disease's steady increase in incidence in the face of proven preventative measures, make the pursuit of a Lyme disease vaccine a worthwhile endeavor. "
11/01/2013 - "Knowledge of the most common ospC genotypes associated specifically with infection of dogs will facilitate the rational design of OspC-based canine Lyme disease vaccines and diagnostic assays."
07/01/2000 - "burgdorferi infection is complex and may be further confounded by the immune response to the recombinant outer surface protein A (OspA) Lyme disease vaccine. "

01/01/2021 - "Control of ixodid ticks and prevention of tick-borne diseases in the United States: The prospect of a new Lyme disease vaccine and the continuing problem with tick exposure on residential properties."
04/01/1999 - "Maximum public health benefit can be achieved only if the Lyme disease vaccines are integrated into broad individual and community-based efforts to prevent Lyme disease and other tick-borne diseases. "
01/01/2021 - "The prospect of a new Lyme disease vaccine for use in humans provides hope for substantial reduction in the >450,000 estimated annual cases of Lyme disease but this breakthrough would not reduce cases of other tick-borne diseases, such as anaplasmosis, babesiosis, ehrlichiosis, spotted fever group rickettsiosis, and Powassan encephalitis. "