Multicystic Dysplastic Kidney (Multicystic Kidney)

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71 relevant articles (1 outcomes, 2 trials/studies) found for this Disease

Description: A nongenetic defect due to malformation of the KIDNEY which appears as a bunch of grapes with multiple renal cysts but lacking the normal renal bean shape, and the collection drainage system. This condition can be detected in-utero with ULTRASONOGRAPHY.

Also Known As:

Multicystic Kidney; Bilateral Multicystic Dysplastic Kidneys; Multicystic Kidney Dysplasia; Multicystic Renal Dysplasia; Unilateral Multicystic Dysplastic Kidney; Dysplasia, Multicystic Kidney; Dysplasia, Multicystic Renal; Dysplasias, Multicystic Kidney; Dysplasias, Multicystic Renal; Kidney Dysplasia, Multicystic; Kidney Dysplasias, Multicystic; Multicystic Dysplastic Kidneys; Multicystic Kidney Dysplasias; Multicystic Kidneys; Multicystic Renal Dysplasias; Renal Dysplasia, Multicystic; Renal Dysplasias, Multicystic

Relationship Network

Disease Context: Research Results

Male Urogenital Diseases

Urologic Diseases: 379

Kidney Diseases: 4269

Cystic Kidney Diseases: 212

Multicystic Dysplastic Kidney: 71

Urogenital Abnormalities: 41

Multicystic Dysplastic Kidney: 71

Female Urogenital Diseases and Pregnancy Complications

Female Urogenital Diseases

Urologic Diseases: 379

Kidney Diseases: 4269

Cystic Kidney Diseases: 212

Multicystic Dysplastic Kidney: 71

Urogenital Abnormalities: 41

Multicystic Dysplastic Kidney: 71

Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 421

Congenital Abnormalities: 9330

Urogenital Abnormalities: 41

Multicystic Dysplastic Kidney: 71

Related Diseases

1.	Hypertension (High Blood Pressure)
2.	Hydronephrosis
3.	Polydactyly (Polydactylism)
4.	Polycystic Kidney Diseases (Polycystic Kidney Disease)
5.	Cysts

Experts

1.	De Grazia, Enrico: 1 article (07/2007)
2.	Cimador, Marcello: 1 article (07/2007)
3.	Carta, Maurizio: 1 article (07/2007)
4.	Giuffrè, Mario: 1 article (07/2007)
5.	Corsello, Giovanni: 1 article (07/2007)
6.	Di Pace, Maria Rita: 1 article (07/2007)
7.	Sergio, Maria: 1 article (07/2007)
8.	Martín Osorio, J A: 1 article (04/2006)
9.	Piró Biosca, C: 1 article (04/2006)
10.	Barceló Cañellas, C: 1 article (04/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Multicystic Dysplastic Kidney:

1.	Transcription Factors (Transcription Factor)IBA 06/01/2001 - "Immunohistochemical studies on the younger sibling revealed hyperproliferative dysplastic kidney tubules which overexpressed PAX2, a potentially oncogenic transcription factor, and BCL2, a cell-survival factor, surrounded by metaplastic, alpha smooth-muscle actin-positive stroma: similar patterns have been observed in patients with non-syndromic multicystic dysplastic kidneys" 06/01/2008 - "Transcription factor 2 gene mutation may be responsible for approximately one-third of children having isolated renal cysts, multicystic dysplastic kidneys, oligomeganephronia, hypo-dysplastic kidneys, horseshoe kidneys, and hyperechogenic kidneys" Order ALL the reference details at left...
2.	ReninIBA 10/01/2002 - "Reduced renin expression and altered gene transcript profiles in multicystic dysplastic kidneys." 11/01/2001 - "CONCLUSIONS: Our observations suggest that multicystic dysplastic kidney may have the ability to produce renin" 11/01/2001 - "RESULTS: Immunostaining of renin was observed in 26 of 29 multicystic dysplastic kidneys (90%)" 11/01/2001 - "To assess renin production we examined the distribution of renin containing cells in multicystic dysplastic kidneys using immunohistochemical methods" 11/01/2001 - "Renin containing cells are present predominantly in scarred areas but not in dysplastic regions in multicystic dysplastic kidney." Order ALL the reference details at left...
3.	Triad FDA Link 01/01/1974 - "The radiological diagnosis of congenital multicystic kidney 'Radiological Triad'." 12/01/1973 - "Roentgenologic triad of congenital multicystic kidney." 03/01/2007 - "The classic MKS triad of occipital encephalocele, postaxial polydactyly, and bilateral enlarged multicystic kidneys can be diagnosed before the 14th gestational weeks by ultrasonography" 01/02/1995 - "The Meckel syndrome (MS) is an autosomal recessive disorder classically defined by the triad of occipital encephalocele, multicystic kidneys, and polydactyly" Order ALL the reference details at left...
4.	A 17 (A-17)IBA 01/01/2002 - "In this report we describe a 17 weeks old female fetus with a lumbosacral meningocoele, multicystic renal dysplasia (Potter type IIb) and postaxial polydactyly type A at the left hand and left foot" 03/01/1996 - "A case of a 17 year-old male patient developing renin dependent hypertension 3 years after nephrectomy for multicystic dysplastic kidney is reported" Order ALL the reference details at left...
5.	Phospholipase C gammaIBA 12/01/2001 - "Pathologically, plc-gamma1(-/-) chimeras showed multicystic kidney due to severe renal dysplasia and renal tube dilation" Order ALL the reference details at left...
6.	Type 2 Angiotensin ReceptorIBA 04/01/2001 - "BACKGROUND: It has been recently found that mice, especially males, with a disrupted angiotensin type 2 receptor (AT2R) gene, which is located on the X-chromosome, often have a range of congenital anomalies of the kidney and urinary tract (CAKUT), including renal hypoplasia, and that Caucasian male patients with ureteropelvic junction stenosis (UPJ) and multicystic dysplastic kidneys frequently have A-G transition in intron 1 of the AT2R gene" Order ALL the reference details at left...
7.	Galectin 3 (LGALS3)IBA 11/01/1997 - "In human multicystic dysplastic kidneys, all diseased epithelia had an embryonic apical expression pattern of galectin-3 and, in addition, all cystic epithelia in autosomal recessive polycystic kidneys expressed this molecule" Order ALL the reference details at left...
8.	Protein Isoforms (Isoforms)IBA 05/01/1994 - "GST expression was also studied in multicystic renal dysplasia, autosomal recessive polycystic kidney disease, and autosomal dominant polycystic kidney disease to determine whether the patterns of expression of alpha and pi isoforms allow identification of the origin of the cysts that characterize these diseases" Order ALL the reference details at left...
9.	RadiopharmaceuticalsIBA 01/01/1995 - "Infantile renal dysplasias, including multicystic dysplastic kidneys (MCDK), are reported rarely to accumulate radiopharmaceuticals on renal scintigraphy" Order ALL the reference details at left...
10.	Technetium Tc 99m Mertiatide FDA Link 06/01/1994 - "Multicystic dysplastic kidney: another application of 99mTc MAG3." Order ALL the reference details at left...

Therapies and Procedures

1.	Nephrectomy 09/01/1994 - "Improved technique of laparoscopic nephrectomy for multicystic dysplastic kidney." 08/01/1998 - "A clinical study of 204 patients with unilateral multicystic renal dysplasia referred to 30 nephrology departments was undertaken to assess the frequency of complications in children who underwent nephrectomy (n = 40) versus those who were treated conservatively (n = 164)" 10/01/2007 - "MATERIALS AND METHODS: A retrospective review of the last 6 years was performed of consecutive open pyeloplasties for ureteropelvic junction obstruction and open nephrectomy for multicystic dysplastic kidneys and renal duplication anomalies at a tertiary hospital for children" 10/01/2006 - "Multicystic dysplastic kidney (MCDK), Wilms' tumour and vesico-ureteric reflux (VUR) accounted for more than half of the nephrectomies (60% and 68% for 1990-1995 and 1996-2001, respectively)" 04/01/2006 - "Multicystic Kidney: is there any new scientific evidence to recommend nephrectomy?]" Order ALL the reference details at left...
2.	Decompression 01/01/1992 - "Re: Percutaneous decompression: treatment for respiratory distress secondary to multicystic dysplastic kidney." 07/01/1990 - "Percutaneous decompression: treatment for respiratory distress secondary to multicystic dysplastic kidney." 12/01/1988 - "With injection of contrast medium, definitive diagnoses were made of a multicystic dysplastic kidney on one side and an obstructed hydronephrotic kidney on the other, thereby directing decompression of the obstructed kidney to preserve native renal function" 07/01/1990 - "We present a case of ultrasound-guided percutaneous cyst decompression used as definitive treatment of respiratory failure associated with multicystic dysplastic kidney." Order ALL the reference details at left...
3.	Surgical Instruments (Clip) 09/01/1994 - "We report removal of a multicystic dysplastic kidney with a laparoscopic technique that uses only three trocar sites" Order ALL the reference details at left...
4.	Replantation 03/01/2004 - "Laparoscopic surgical procedures performed included right upper pole partial nephrectomy, left upper pole partial nephroureterectomy, removal of left multicystic dysplastic kidney and bilateral Cohen reimplantation of ureters" Order ALL the reference details at left...
5.	Laparotomy 03/01/1984 - "The patient was diagnosed to have a left congenital unilateral multicystic kidney, and laparotomy was performed" Order ALL the reference details at left...

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