|1.||Brodeur, G M: 6 articles (01/2001 - 04/2000)|
|2.||Eggert, A: 6 articles (01/2001 - 04/2000)|
|3.||Ikegaki, N: 6 articles (01/2001 - 04/2000)|
|4.||Cattaneo, Antonino: 5 articles (10/2013 - 07/2004)|
|5.||Lazarovici, Philip: 4 articles (01/2007 - 06/2003)|
|6.||Liu, X G: 4 articles (01/2001 - 07/2000)|
|7.||Eggert, Angelika: 3 articles (11/2014 - 03/2002)|
|8.||Covaceuszach, Sonia: 3 articles (01/2011 - 07/2004)|
|9.||Saragovi, H Uri: 3 articles (06/2007 - 02/2004)|
|10.||Davidson, Ben: 3 articles (01/2007 - 06/2003)|
06/01/2007 - "Ultrastructural localization of the neurotrophin receptor (TrkA) in cultured rat pheochromocytoma PC12 Cells: three-dimensional image analysis by high voltage electron microscopy."
04/01/2005 - "In rat pheochromocytoma (PC12) cells, tyrosine kinase A receptor (TrkA) mediates neurotrophic or protective effects, while p75 neurotrophin receptor (p75NTR) functions as a death receptor. "
11/01/1999 - "Nerve growth factor (NGF) induces differentiation of the rat pheochromocytoma clone (PC12) by activating the high affinity receptor, p140(trkA), linked to mitogen-activated protein kinase. "
01/01/1997 - "v-Crk is a member of a class of SH2 and SH3-containing adaptor proteins that have been implicated in regulating the TrkA receptor tyrosine kinase and potentiating Nerve Growth Factor (NGF)-mediated neurite outgrowth in pheochromocytoma (PC12) cells (Hempstead et al, Mol. "
08/20/1999 - "We have shown recently in the pheochromocytoma PC-12 cell line, that the activation of the high-affinity receptor for nerve growth factor (NGF), tyrosine kinase receptor (TrkA), results in increased secretion of the amyloid precursor protein (APP) into the culture medium. "
04/01/2011 - "Interestingly, the p-trkA receptor expression level showed the most significant difference and its presence was only found in borderline tumor and EOC samples indicating the importance of trkA receptor in EOC as a potential tumor marker. "
10/28/2003 - "These novel PC models facilitate research on the role of the trkA receptor in cancer and the development of trkA-selective anti-cancer agents."
10/28/2003 - "We report the establishment of PC12 tumor models expressing low and high levels of trkA receptor in CD1 nude mice. "
10/14/1999 - "Altered expression of the trkA gene or trkA receptor malfunction have been implicated in neurodegeneration, tumor progression and oncogenesis. "
11/30/2014 - "In neuroblastoma, the most common solid tumor of childhood, excellent prognosis is associated with extensive Schwann cell (SC) content and high-level expression of the neurotrophin receptor, NTRK1/TrkA, which is known to mediate neuroblastoma cell differentiation. "
02/20/2007 - "This study represents a direct demonstration that neutralizing antibodies directed against the TrkA receptor may display potent analgesic effects in inflammatory and chronic pain."
08/01/2015 - "An alternative for fracture-related pain treatment may be blockade of nerve growth factor (NGF)/neurotrophic tyrosine kinase receptor type 1 (TrkA) signaling. "
07/11/2014 - "Syntaxin 8 modulates the post-synthetic trafficking of the TrkA receptor and inflammatory pain transmission."
02/01/2010 - "Nerve growth factor (NGF) is involved in pain transduction mechanisms, playing a key role as a master switch in many chronic and inflammatory pain states; the NGF ligand and its receptor TrkA constitute well-validated targets for pain therapy. "
06/01/2009 - "There is considerable evidence showing that the system constituted by the NGF and its high-affinity receptor TrkA plays a fundamental role in the molecular processes underlying the main forms of "persistent" pain. "
09/01/2004 - "Based on the extent of SP and trkA co-expression in airway-specific neurons by NGF treatment, the present study suggests that, following a peripheral activation of trkA receptor on SP afferent by NGF which is elevated in allergic inflammation, there may be trkA-mediated SP induction to mediate neurogenic airway inflammation."
08/20/2012 - "The level of NGF high affinity receptor TrkA mRNA was also increased in both the urothelium and the smooth muscle layers during bladder inflammation. "
06/01/2014 - "Rats exposed to neonatal inflammation also showed up-regulation of spinal NGF, TrkA receptor, BDNF, TrkB receptor, IL-1β, and COX-2 expression following the second BV injection, especially with prior BV exposure on postnatal day 21 or 28. "
05/01/2000 - "Synovium of 15 patients with RA in active phase and synovium of 14 patients without synovial inflammation were processed for histochemical (NADPH-diaphorase) and immunohistochemical visualization of different isoforms for the NO synthesis enzyme NO synthase (NOS) and for NGF high affinity receptor trkA. "
12/01/2009 - "The results of this study suggest that an autocrine loop between NGF and its receptor TrkA is activated in pterygium and that it is involved in the angiogenic response taking place in this pathological condition. "
12/01/2009 - "Results showed that endothelial cells in human pterygium are immunoreactive to both NGF and its receptor TrkA, and that this immunoreactivity is correlated to microvascular density. "
|1.||Protein-Tyrosine Kinases (Tyrosine Kinase)
|2.||Nerve Growth Factor Receptor (Nerve Growth Factor Receptor, Low Affinity)
|3.||Nerve Growth Factor (NGF)
|5.||Nerve Growth Factor Receptors (Neurotrophin Receptors)
|7.||Angiogenesis Inducing Agents (Angiogenesis Factor)
|10.||Messenger RNA (mRNA)