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Conotoxins (Conotoxin)

Peptide neurotoxins from the marine fish-hunting snails of the genus CONUS. They contain 13 to 29 amino acids which are strongly basic and are highly cross-linked by disulfide bonds. There are three types of conotoxins, omega-, alpha-, and mu-. OMEGA-CONOTOXINS inhibit voltage-activated entry of calcium into the presynaptic membrane and therefore the release of ACETYLCHOLINE. Alpha-conotoxins inhibit the postsynaptic acetylcholine receptor. Mu-conotoxins prevent the generation of muscle action potentials. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
Also Known As:
Conotoxin; alpha-Conotoxin; mu-Conotoxin; alpha Conotoxin; alpha Conotoxins; mu Conotoxin; mu Conotoxins; alpha-Conotoxins; mu-Conotoxins
Networked: 172 relevant articles (11 outcomes, 18 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Adams, David J: 24 articles (01/2022 - 06/2004)
2. Craik, David J: 19 articles (01/2020 - 06/2004)
3. Lewis, Richard J: 14 articles (02/2021 - 06/2004)
4. Alewood, Paul F: 10 articles (03/2019 - 11/2006)
5. Luo, Sulan: 9 articles (12/2021 - 04/2016)
6. Vetter, Irina: 9 articles (02/2021 - 01/2012)
7. Clark, Richard J: 9 articles (01/2018 - 03/2008)
8. Zhangsun, Dongting: 8 articles (04/2020 - 04/2016)
9. McIntosh, J Michael: 7 articles (01/2021 - 03/2008)
10. Tae, Han-Shen: 7 articles (01/2021 - 04/2016)

Related Diseases

1. Neuralgia (Stump Neuralgia)
2. Chronic Pain
3. Pain (Aches)
4. Hyperalgesia
5. Schizophrenia (Dementia Praecox)

Related Drugs and Biologics

1. Analgesics (Analgesic Drugs)
2. Peptides (Polypeptides)
3. Nicotinic Receptors (Nicotinic Acetylcholine Receptor)
4. ziconotide (Prialt)
5. Venoms
6. Calcium Channels (Calcium Channel)
7. Opioid Analgesics (Opioids)
8. Neuroprotective Agents
9. Electrolytes
10. Cholinesterases (Cholinesterase)

Related Therapies and Procedures

1. Therapeutics
2. Analgesia
3. Injections
4. Drug Therapy (Chemotherapy)
5. Intralesional Injections