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Conotoxins (Conotoxin)

Peptide neurotoxins from the marine fish-hunting snails of the genus CONUS. They contain 13 to 29 amino acids which are strongly basic and are highly cross-linked by disulfide bonds. There are three types of conotoxins, omega-, alpha-, and mu-. OMEGA-CONOTOXINS inhibit voltage-activated entry of calcium into the presynaptic membrane and therefore the release of ACETYLCHOLINE. Alpha-conotoxins inhibit the postsynaptic acetylcholine receptor. Mu-conotoxins prevent the generation of muscle action potentials. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
Also Known As:
Conotoxin; alpha-Conotoxin; mu-Conotoxin; alpha Conotoxin; alpha Conotoxins; mu Conotoxin; mu Conotoxins; alpha-Conotoxins; mu-Conotoxins
Networked: 96 relevant articles (10 outcomes, 10 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Adams, David J: 12 articles (02/2015 - 06/2004)
2. Craik, David J: 12 articles (01/2015 - 06/2004)
3. Lewis, Richard J: 9 articles (10/2015 - 06/2004)
4. Alewood, Paul F: 6 articles (10/2015 - 11/2006)
5. Vetter, Irina: 6 articles (10/2015 - 01/2012)
6. Daly, Norelle L: 6 articles (03/2012 - 06/2004)
7. Clark, Richard J: 6 articles (03/2012 - 03/2008)
8. Kaas, Quentin: 4 articles (01/2015 - 12/2011)
9. Berecki, Géza: 4 articles (01/2015 - 10/2008)
10. McIntosh, J Michael: 4 articles (10/2014 - 03/2008)

Related Diseases

1. Pain (Aches)
2. Neuralgia (Stump Neuralgia)
3. Hyperalgesia
4. Schizophrenia (Dementia Praecox)
5. Intractable Pain

Related Drugs and Biologics

1. Conotoxins (Conotoxin)
2. ziconotide (Prialt)
3. Nicotinic Receptors (Nicotinic Acetylcholine Receptor)
4. Venoms
5. Opioid Analgesics (Opioids)
6. Neuroprotective Agents
7. Drosophila acetylcholine receptor alpha-subunit
8. Peptides
9. Sodium Channels (Sodium Channel)
10. Calcium Channels (Calcium Channel)

Related Therapies and Procedures

1. Analgesia
2. Intralesional Injections
3. Spinal Injections
4. Injections