|1.||Chiron, Catherine: 10 articles (01/2015 - 09/2002)|
|2.||Luszczki, Jarogniew J: 10 articles (01/2014 - 01/2004)|
|3.||Westall, Carol A: 8 articles (12/2014 - 11/2003)|
|4.||Snead, O Carter: 7 articles (08/2015 - 01/2002)|
|5.||Dulac, Olivier: 7 articles (01/2015 - 09/2002)|
|6.||Silverman, Richard B: 6 articles (02/2015 - 09/2002)|
|7.||Edwards, Stuart W: 6 articles (09/2013 - 11/2004)|
|8.||Osborne, John P: 6 articles (09/2013 - 11/2004)|
|9.||Marson, Anthony G: 6 articles (01/2013 - 01/2008)|
|10.||Riikonen, Raili: 5 articles (05/2015 - 06/2004)|
|1.||Infantile Spasms (West Syndrome)
03/01/2012 - "Clinical studies have shown that vigabatrin is superior to placebo in decreasing the frequency of infantile spasms. "
05/01/2010 - "Vigabatrin is particularly effective for the treatment of patients with West syndrome; however, the patients need to be regularly monitored for the development of peripheral visual field defect. "
03/01/2008 - "Vigabatrin has proved to be effective against infantile spasms due to TSC. "
11/01/2003 - "This is a particular problem as vigabatrin is effective against infantile spasms. "
09/01/2002 - "Vigabatrin is an effective, well-tolerated treatment for infantile spasms. "
02/01/1993 - "Clinical efficacy of vigabatrin has been evaluated in controlled trials and appears to be most effective in complex partial seizures, producing a 50 percent or greater reduction in seizure frequency in approximately 50 percent of the adult patients studied. "
04/01/2000 - "Vigabatrin has been found most effective against complex partial and secondarily generalized tonic-clonic seizures in both adults and children. "
07/01/1988 - "From patients who showed a greater than 50% reduction in seizures (responders) or marked improvement in global performance, a third sample was taken at the end of the next 3-month phase, during which 3 g or 1.5 g gamma-vinyl GABA had been administered daily. "
12/01/1996 - "The results of this study indicate that vigabatrin, given in a daily dose of either 2 g or 3 g is significantly more effective than placebo in reducing seizure frequency among patients with partial seizures."
01/01/2011 - "Efficacy outcomes demonstrated that vigabatrin add-on therapy significantly reduced the frequency of seizures. "
02/01/2012 - "Vigabatrin was effective for refractory childhood partial-onset epilepsy, and was not associated with symptomatic vision loss."
02/01/1993 - "Vigabatrin has been effective in patients with refractory epilepsy. "
01/01/1989 - "6. Vigabatrin thus appears to be a safe antiepileptic drug that may be effective in the treatment of severe epilepsy in children."
09/01/1994 - "To determine the efficacy of a new anti-epileptic medication vigabatrin in adults and children with drug-resistant epilepsy. "
12/01/2013 - "This study evaluated the efficacy of Vigabatrin in children with intractable epilepsy. "
|4.||Tuberous Sclerosis (Bourneville's Disease)
03/01/2012 - "In tuberous sclerosis, vigabatrin may be considered the first-line treatment for IS. "
01/01/2004 - "Vigabatrin has shown promise in treating IS patients, particularly those with tuberous sclerosis. "
07/01/1998 - "However, since 1990, some authors have reported the efficacy of vigabatrin (VGB), especially in cases related to tuberous sclerosis. "
02/01/1999 - "Paradoxically, in those without tuberous sclerosis complex, vigabatrin might be less efficacious than suggested by studies including patients with tuberous sclerosis complex."
08/01/1997 - "To study the pharmacokinetics of vigabatrin in a patient affected with tuberous sclerosis who developed major agitation and aggression, while receiving vigabatrin orally (1.5 g every 12 h) and in whom impaired renal function was diagnosed. "
|5.||Partial Epilepsies (Epilepsy, Partial)
12/01/1993 - "Vigabatrin is most effective in drug-resistant partial epilepsy. "
12/01/1994 - "More specifically, vigabatrin, which is a very useful and well tolerated new antiepileptic drug for refractory partial epilepsy, should be started at a low dosage of 0.5 g/day with increments of 0.5 g/day every week. "
05/01/1999 - "These results suggest that vigabatrin may be an alternative first-line treatment for childhood partial epilepsies. "
01/01/2013 - "We included randomised, double-blind, placebo-controlled, fully published trials of vigabatrin in people with drug-resistant partial epilepsy. "
12/01/2010 - "Reports, published in full, of observational studies investigating the prevalence of visual field loss in patients with partial epilepsy treated with vigabatrin were included. "
|2.||Adrenocorticotropic Hormone (ACTH)
|5.||gamma-Aminobutyric Acid (GABA)
|8.||Anticonvulsants (Antiepileptic Drugs)
|10.||Valproic Acid (Valproate, Semisodium)
|1.||Vagus Nerve Stimulation
|3.||Psychology Biofeedback (Biofeedback)