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Subtilisin

A serine endopeptidase isolated from Bacillus subtilis. It hydrolyzes proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. It also hydrolyzes peptide amides. (From Enzyme Nomenclature, 1992) EC 3.4.21.62.
Networked: 410 relevant articles (13 outcomes, 46 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Seidah, Nabil G: 12 articles (11/2018 - 04/2005)
2. Blackman, Michael J: 6 articles (01/2020 - 07/2004)
3. Pan, Jihong: 6 articles (07/2018 - 02/2015)
4. Hegele, Robert A: 5 articles (03/2021 - 11/2013)
5. Withers-Martinez, Chrislaine: 5 articles (01/2020 - 07/2004)
6. Wang, Lin: 5 articles (07/2018 - 02/2015)
7. Abifadel, Marianne: 5 articles (01/2017 - 11/2010)
8. Boileau, Catherine: 5 articles (01/2017 - 11/2010)
9. Koskinas, Konstantinos C: 4 articles (05/2022 - 11/2017)
10. Räber, Lorenz: 4 articles (05/2022 - 11/2017)

Related Diseases

1. Hypercholesterolemia
2. Cardiovascular Diseases (Cardiovascular Disease)
3. Infections
4. Dyslipidemias (Dyslipidemia)
5. Hyperlipoproteinemia Type II (Familial Hypercholesterolemia)

Related Drugs and Biologics

1. Proprotein Convertases (Pro-Opiomelanocortin Converting Enzyme)
2. PCSK9 Inhibitors
3. Peptide Hydrolases (Proteases)
4. Lipids
5. oxidized low density lipoprotein
6. Enzymes
7. Proteins (Proteins, Gene)
8. Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)
9. Monoclonal Antibodies
10. Peptides (Polypeptides)

Related Therapies and Procedures

1. Therapeutics
2. Blood Component Removal (Apheresis)
3. Secondary Prevention
4. Percutaneous Coronary Intervention
5. Gastric Bypass (Roux-en-Y Gastric Bypass)