Chimerin 1
A GTPase activating protein that is specific for RAC GTP-BINDING PROTEINS. It is expressed primarily in the brain and may be involved in signal transduction. The alternatively spliced form of CHIMERIN 1 (alpha-2 Chimerin) contains an additional src homology domain and is expressed in both the brain and testes.
Also Known As:
Chimaerin 1; alpha-1 Chimaerin; alpha-2 Chimaerin; alpha-Chimaerin; alpha1-Chimaerin; n-Chimaerin; Chimaerin, alpha-1; Chimaerin, alpha-2; Chimerin, alpha-1; Chimerin, alpha-2; alpha 1 Chimaerin; alpha 1 Chimerin; alpha 2 Chimaerin; alpha 2 Chimerin; alpha Chimaerin; alpha Chimerin; alpha1 Chimaerin; n Chimaerin; alpha-1 Chimerin; alpha-2 Chimerin; alpha-Chimerin; arhGAP2 Protein; n-Chimerin; rhoGAP2 Protein
Networked: 5
relevant articles (0 outcomes,
0 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Biler, Elif Demirkilinc:
1 article
(12/2017)
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2. | Ilim, Orhan:
1 article
(12/2017)
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3. | Onay, Huseyin:
1 article
(12/2017)
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4. | Uretmen, Onder:
1 article
(12/2017)
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5. | Akatsu, Hiroyasu:
1 article
(03/2015)
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6. | Beach, Thomas G:
1 article
(03/2015)
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7. | Kato, Tomoko:
1 article
(03/2015)
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8. | Konishi, Yoshihiro:
1 article
(03/2015)
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9. | Shimohama, Shun:
1 article
(03/2015)
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10. | Tooyama, Ikuo:
1 article
(03/2015)
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Related Diseases
1. | Neuroblastoma
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2. | Philadelphia Chromosome
12/15/1990
- " A human brain-specific cDNA encoding n-chimaerin, a protein of predicted molecular mass 34 kDa, has sequence identity with two different proteins: protein kinase C (PKC) at the N-terminus and BCR protein [product of the breakpoint-cluster-region (BCR) gene, involved in Philadelphia chromosome translocation] at the C-terminus [Hall, Monfries, Smith, Lim, Kozma, Ahmed, Vannaisungham, Leung & Lim (1990) J. "
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3. | Duane Retraction Syndrome (Duane Syndrome)
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4. | Alzheimer Disease (Alzheimer's Disease)
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