|1.||Clarke, Robert: 21 articles (12/2015 - 06/2002)|
|2.||Lykkesfeldt, Anne E: 16 articles (01/2015 - 03/2003)|
|3.||Arteaga, Carlos L: 13 articles (01/2015 - 01/2003)|
|4.||Jordan, V Craig: 12 articles (12/2015 - 01/2002)|
|5.||Miller, Todd W: 11 articles (02/2014 - 05/2009)|
|6.||Riggins, Rebecca B: 10 articles (01/2015 - 06/2004)|
|7.||Sutherland, Robert L: 10 articles (07/2012 - 06/2002)|
|8.||Nicholson, Robert I: 9 articles (12/2014 - 01/2002)|
|9.||Nephew, Kenneth P: 9 articles (01/2012 - 10/2002)|
|10.||Jelovac, Danijela: 9 articles (05/2007 - 07/2002)|
|1.||Breast Neoplasms (Breast Cancer)
05/01/1984 - "Since very useful non-steroidal antiestrogens have been synthesized recently, the usefulness of drug-based endocrine therapy for breast cancer has become more important compared with brought about by surgical therapy. "
02/01/2012 - "Antiestrogen therapy has been used successfully to prolong disease-free and overall survival of ER positive breast cancer patients. "
10/15/2010 - "These observations suggest 1 mechanism whereby AIs, which block E(2) synthesis, would be more effective for breast cancer prevention than use of antiestrogens, which only block ER-mediated effects."
12/01/2013 - "Taken together, our findings identify SHON as a novel human oncogene with predictive utility in ER(+) breast cancer, perhaps offering a simple biomarker to predict the therapeutic efficacy of antiestrogen therapy in patients with breast cancer."
01/01/2011 - "Consistent support for the hypothesis that antiestrogens are effective in reducing contralateral breast cancer risks is available from the literature. "
10/01/2011 - "This novel treatment strategy may be most effective in women with antiestrogen insensitive tumors, a patient population with historically poor response to traditional therapies."
12/01/1977 - "Our data suggest that canine mammary tumors with significant ER levels would respond favorably to antiestrogen therapy. "
06/01/2003 - "The results suggest that in ER+ tumors, FR-alpha expression is directly and actively suppressed and predict that a brief treatment with antiestrogens will boost FR-alpha expression by passive derepression, enhancing the efficacy of FR-targeted diagnostic and therapeutic applications. "
07/01/1998 - "Both antiestrogens were effective in reducing tumor growth in these mice. "
02/01/1985 - "Both antiestrogens were effective in delaying the development of secondary tumors, especially during the time of treatment. "
12/01/2001 - "Based on this and another case reported in the literature, we believe that antiestrogen therapy could prove beneficial in a subset of patients with sweat gland carcinoma. "
01/01/2004 - "The aim of this study was to determine whether Z-(123)I-MIVE scintigraphy is able to predict response or resistance to antiestrogen therapy in patients with metastatic ER-positive breast carcinoma. "
03/01/1987 - "This study attempts to investigate the in vitro effects of E and antiestrogen (AE) on promoting cell proliferation and the cell cycle kinetics of an experimental mammary carcinoma model, CAMA-1. "
06/28/2013 - "This DDS was designed to deliver miproxifen phosphate (TAT-59), an antiestrogen drug, to ductal lesions via the milk duct, where carcinomas originate, more efficiently than systemic administration, using an iontophoretic technique applied to the nipple (IP administration). "
02/15/2011 - "At the human equivalent molar dose of TAM (0.33 or 1.0 mg/kg), SS5020 had much stronger antitumor potential than those same antiestrogens against 7,12-dimethylbenz(a)anthracene-induced mammary carcinoma in rats. "
|4.||Ovarian Neoplasms (Ovarian Cancer)
01/01/2004 - "However, response to antiestrogen drugs in BRCA1-blocked ER-positive ovarian cancer cells has not been reported, and this served as the rationale for this study. "
12/01/1987 - "These results indicated that ovarian cancer containing ER, even though it originated from germ cells, would be responsible for antiestrogen therapy."
07/01/2001 - "The finding of a lower apoptotic activity in tumors with a high expression of ER and an indication of increased proliferation in areas with high ER density gives a rationale for antiestrogen therapy even in poorly differentiated epithelial ovarian cancers. "
01/01/2013 - "Estrogen exposure has at least a moderate effect on the risk for ovarian cancer, and antiestrogen therapy may be helpful in treating the disease. "
09/16/2013 - "Data on the efficacy and safety of antiestrogens and aromatase inhibitors in recurrent ovarian cancer have been accumulated through phase II clinical studies. "
|5.||Neoplasm Metastasis (Metastasis)
06/28/2007 - "Estimated and true 5-10 year overall survival rates from first line antiestrogen and distant metastases were higher than previously reported in a similar population. "
01/01/2003 - "The patient received antiestrogen therapy but subsequently developed skeletal metastases. "
02/01/2006 - "Ninety-seven postmenopausal patients with axillary lymph node metastasis were treated with an antiestrogen for a period of 3 years after primary surgery and radiotherapy. "
03/01/2014 - "Our results indicate that targeting the GPR30 signaling may be a potential strategy to reduce metastasis and improve the efficacy of antiestrogens in treatment of advanced breast cancer. "
09/01/2007 - "In sum, loss of p27 activated AIB1, E2F1, Gab2, and Akt; increased cell migration and invasion; caused antiestrogen insensitivity; and promoted metastasis of breast cancer cells. "
|8.||Progesterone Receptors (Progesterone Receptor)
|3.||Heterologous Transplantation (Xenotransplantation)
|4.||Drug Therapy (Chemotherapy)